Multimodality imaging to distinguish between benign and malignant cardiac masses

Author(s):  
Ayaz Aghayev ◽  
Michael K. Cheezum ◽  
Michael L. Steigner ◽  
Negareh Mousavi ◽  
Robert Padera ◽  
...  
2020 ◽  
Vol 22 (12) ◽  
Author(s):  
Rossana Bussani ◽  
Matteo Castrichini ◽  
Luca Restivo ◽  
Enrico Fabris ◽  
Aldostefano Porcari ◽  
...  

Abstract Purpose of Review Cardiac masses frequently present significant diagnostic and therapeutic clinical challenges and encompass a broad set of lesions that can be either neoplastic or non-neoplastic. We sought to provide an overview of cardiac tumors using a cardiac chamber prevalence approach and providing epidemiology, imaging, histopathology, diagnostic workup, treatment, and prognoses of cardiac tumors. Recent Findings Cardiac tumors are rare but remain an important component of cardio-oncology practice. Over the past decade, the advances in imaging techniques have enabled a noninvasive diagnosis in many cases. Indeed, imaging modalities such as cardiac magnetic resonance, computed tomography, and positron emission tomography are important tools for diagnosing and characterizing the lesions. Although an epidemiological and multimodality imaging approach is useful, the definite diagnosis requires histologic examination in challenging scenarios, and histopathological characterization remains the diagnostic gold standard. Summary A comprehensive clinical and multimodality imaging evaluation of cardiac tumors is fundamental to obtain a proper differential diagnosis, but histopathology is necessary to reach the final diagnosis and subsequent clinical management.


2020 ◽  
Vol 13 (11) ◽  
pp. 2412-2414
Author(s):  
Juan C. Lopez-Mattei ◽  
Yang Lu

2019 ◽  
Vol 36 (1) ◽  
pp. 52-63
Author(s):  
Eric Kallstrom ◽  
Elizabeth Kallus ◽  
Krista Erbe ◽  
Michael Rampoldi ◽  
Don Le ◽  
...  

A tumor is an excessive growth of cells that results from the body’s inability to balance the growth of new cells and the destruction of old cells. Tumors can occur throughout the body and are classified as either benign or malignant. However, cardiac tumors are a rare occurrence. When present, several imaging modalities are available to illustrate their presence and characteristics. Not all cardiac masses look similar and, depending on their size and location, may pose different health risks to the patient. This case series introduces six left atrial myxomas with dissimilar appearances initially detected by transthoracic echocardiography, along with cross-correlation by transesophageal echocardiography, computed tomography, and mechanical resonance imaging.


Author(s):  
Fengjuan Yao

Background: The clinical manifestations of cardiac masses are diverse and lack specificity. Here we report a cardiacmass detected by transthoracic echocardiography. Multimodality imaging and pathological findings after the operationconfirmed the mass as mediastinal tuberculoma.Case presentation: A 45-year-old male patient was admitted to our hospital reporting chest tightness, weight loss, and dyspnea for 3 months after exercise. Transthoracic echocardiography showed that there were a large number of pericardial effusions and the soft tissue mass measuring 7.7 cm × 4.5 cm in the upper mediastinum, which oppressed the right pulmonary artery and accelerated the blood flow of the left pulmonary artery. Contrast-enhanced ultrasonography showed degenerative inhomogeneous high enhancement of and an unclear boundary in the mass. Contrast-enhanced chest CT revealed punctate and patchy calcification in and uneven enhancement of the mass and the lymph nodes around the aortic arch. The mass was diagnosed as a malignant mediastinal tumor. Pathological analysis of the mass revealed chronic granulomatous tuberculosis. The symptoms abated significantly after antituberculosis treatment. The patientremained asymptomatic during follow-up.Conclusion: This report presents a rare case of mediastinal tuberculoma mimicking a malignant cardiac tumor. Multimodalityimaging should be incorporated for differentiation of cardiac masses.


2021 ◽  
Author(s):  
Xin Xu ◽  
Ping Xu ◽  
Ting Ting Wu ◽  
Guo Dong Shang

Abstract Background: Metastatic cardiac tumors have been reported in up to 25% of patients with lung cancer, but detection of cardiac involvement via pulmonary veins is neither uncommon nor easy in the routine work. Case presentation: A 68-year-old woman with primary lung cancer was admitted to the hospital with pain in her left leg for 6 months and hemoptysis for one week. TTE detected that a hyperechoic mass in the left atrium which was come from the left inferior pulmonary vein. The result was confirmed by computed tomography.Conclusions: Multimodality imaging should be advocated in the evaluation of cardiac masses especially for patient who has primary tumors.


2020 ◽  
Vol 4 (2) ◽  
pp. 1-6 ◽  
Author(s):  
Matteo Castrichini ◽  
Stefano Albani ◽  
Bruno Pinamonti ◽  
Gianfranco Sinagra

Abstract Background Cardiac masses (CM) encompass a broad set of lesions that can be either neoplastic or non-neoplastic. A stepwise diagnostic strategy through multimodality imaging evaluation is the cornerstone for the appropriate approach. Case summary We report the case of an 83-year-old man presenting at the emergency department for acute heart failure showing bilateral atrial masses without unequivocal aetiological aspects at several imaging techniques, emphasizing the critical aspects in the differential diagnosis. Discussion In the complex field of CM, a proper differential diagnosis is very important in order to start the appropriate treatment; however, sometimes it could be challenging despite a multimodality imaging approach, therefore still requiring histologic examination.


Author(s):  
Fatima M Ezzeddine ◽  
Melanie C Bois ◽  
Sorin V Pislaru ◽  
Hartzell V Schaff

Abstract Background Characterization of cardiac masses and anomalies is challenging and usually requires multimodality imaging. Herein, we present the case of a left ventricular chord masquerading as an aortic valve papillary fibroelastoma. Case summary In this case, a 62-year-old woman presented with acute right foot weakness. Brain imaging showed multiple areas of acute infarction concerning for a cardioembolic stroke. Transesophageal echocardiography revealed a mass, which was thought to be a papillary fibroelastoma, attached to the non-coronary cusp of the aortic valve. The patient underwent surgical excision of the mass which turned out to be a left ventricular chord crossing the aortic valve and attaching to the left aortic sinus of Valsalva. Conclusion This case underlines the importance of close examination of the aortic subvalvular apparatus when assessing aortic valve masses.


2009 ◽  
Vol 37 (6) ◽  
pp. 495-515 ◽  
Author(s):  
Ali Fatemi-Ardekani ◽  
Navid Samavati ◽  
Jin Tang ◽  
Markad V. Kamath

Author(s):  
Hale Aydin ◽  
Bahar Guner ◽  
Isil Esen Bostanci ◽  
Nazan Ciledag ◽  
Melda Boyacioglu Bulut ◽  
...  

Background and Objectives: The purpose of this study was to evaluate the mammographic, sonographic and MRI findings of metaplastic breast carcinoma. Methods: In this retrospective review study, we analyzed the medical files of 9600 patients who were treated for invasive breast cancers. Clinical information, histopathologic and radiologic findings of 65 patients were included in this study. All existing radiologic images and medical reports were reviewed retrospectively. Thirty-three patients had MG, 58 patients had US and 7 patients had MRI imaging results. Results: Mammographically, the most frequent presentations of MPBC were round shape, microlobulated margin and high density masses. Calcifications with or without masses were not a frequent finding. The most common sonographic findings were round shape, partially indistinct angular margin, hypoechoic and heterogeneous echo patterns and no posterior feature masses. All lesions were presented as masses rather than non-mass enhancements on magnetic resonance imaging. Features of masses had more malignant feature on MRI than other modalities in all 7 patients. Conclusion: Metaplastic breast carcinoma is one of the rarest poorly differentiated invasive breast carcinomas. Interestingly, these aggressive tumors demonstrate benign or moderately malign features on imaging methods. This appearance of MPBC can cause it to be misdiagnosed as a benign breast lesion especially in young women. MPBC should be kept in mind in the differential diagnosis of large palpable breast masses. Therefore, follow-up at short intervals and/or multimodality imaging studies which include breast MRI are important for the diagnosis of MPBC.


2020 ◽  
Vol 58 (6) ◽  
pp. 1147-1159
Author(s):  
Samuel J. Galgano ◽  
Kedar Sharbidre ◽  
Desiree E. Morgan

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