MutagenPred-GCNNs: A Graph Convolutional Neural Network-Based Classification Model for Mutagenicity Prediction with Data-Driven Molecular Fingerprints

Author(s):  
Shimeng Li ◽  
Li Zhang ◽  
Huawei Feng ◽  
Jinhui Meng ◽  
Di Xie ◽  
...  
2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Young-Gon Kim ◽  
Sungchul Kim ◽  
Cristina Eunbee Cho ◽  
In Hye Song ◽  
Hee Jin Lee ◽  
...  

AbstractFast and accurate confirmation of metastasis on the frozen tissue section of intraoperative sentinel lymph node biopsy is an essential tool for critical surgical decisions. However, accurate diagnosis by pathologists is difficult within the time limitations. Training a robust and accurate deep learning model is also difficult owing to the limited number of frozen datasets with high quality labels. To overcome these issues, we validated the effectiveness of transfer learning from CAMELYON16 to improve performance of the convolutional neural network (CNN)-based classification model on our frozen dataset (N = 297) from Asan Medical Center (AMC). Among the 297 whole slide images (WSIs), 157 and 40 WSIs were used to train deep learning models with different dataset ratios at 2, 4, 8, 20, 40, and 100%. The remaining, i.e., 100 WSIs, were used to validate model performance in terms of patch- and slide-level classification. An additional 228 WSIs from Seoul National University Bundang Hospital (SNUBH) were used as an external validation. Three initial weights, i.e., scratch-based (random initialization), ImageNet-based, and CAMELYON16-based models were used to validate their effectiveness in external validation. In the patch-level classification results on the AMC dataset, CAMELYON16-based models trained with a small dataset (up to 40%, i.e., 62 WSIs) showed a significantly higher area under the curve (AUC) of 0.929 than those of the scratch- and ImageNet-based models at 0.897 and 0.919, respectively, while CAMELYON16-based and ImageNet-based models trained with 100% of the training dataset showed comparable AUCs at 0.944 and 0.943, respectively. For the external validation, CAMELYON16-based models showed higher AUCs than those of the scratch- and ImageNet-based models. Model performance for slide feasibility of the transfer learning to enhance model performance was validated in the case of frozen section datasets with limited numbers.


Sensors ◽  
2021 ◽  
Vol 21 (14) ◽  
pp. 4916
Author(s):  
Ali Usman Gondal ◽  
Muhammad Imran Sadiq ◽  
Tariq Ali ◽  
Muhammad Irfan ◽  
Ahmad Shaf ◽  
...  

Urbanization is a big concern for both developed and developing countries in recent years. People shift themselves and their families to urban areas for the sake of better education and a modern lifestyle. Due to rapid urbanization, cities are facing huge challenges, one of which is waste management, as the volume of waste is directly proportional to the people living in the city. The municipalities and the city administrations use the traditional wastage classification techniques which are manual, very slow, inefficient and costly. Therefore, automatic waste classification and management is essential for the cities that are being urbanized for the better recycling of waste. Better recycling of waste gives the opportunity to reduce the amount of waste sent to landfills by reducing the need to collect new raw material. In this paper, the idea of a real-time smart waste classification model is presented that uses a hybrid approach to classify waste into various classes. Two machine learning models, a multilayer perceptron and multilayer convolutional neural network (ML-CNN), are implemented. The multilayer perceptron is used to provide binary classification, i.e., metal or non-metal waste, and the CNN identifies the class of non-metal waste. A camera is placed in front of the waste conveyor belt, which takes a picture of the waste and classifies it. Upon successful classification, an automatic hand hammer is used to push the waste into the assigned labeled bucket. Experiments were carried out in a real-time environment with image segmentation. The training, testing, and validation accuracy of the purposed model was 0.99% under different training batches with different input features.


2021 ◽  
Vol 11 (9) ◽  
pp. 4292
Author(s):  
Mónica Y. Moreno-Revelo ◽  
Lorena Guachi-Guachi ◽  
Juan Bernardo Gómez-Mendoza ◽  
Javier Revelo-Fuelagán ◽  
Diego H. Peluffo-Ordóñez

Automatic crop identification and monitoring is a key element in enhancing food production processes as well as diminishing the related environmental impact. Although several efficient deep learning techniques have emerged in the field of multispectral imagery analysis, the crop classification problem still needs more accurate solutions. This work introduces a competitive methodology for crop classification from multispectral satellite imagery mainly using an enhanced 2D convolutional neural network (2D-CNN) designed at a smaller-scale architecture, as well as a novel post-processing step. The proposed methodology contains four steps: image stacking, patch extraction, classification model design (based on a 2D-CNN architecture), and post-processing. First, the images are stacked to increase the number of features. Second, the input images are split into patches and fed into the 2D-CNN model. Then, the 2D-CNN model is constructed within a small-scale framework, and properly trained to recognize 10 different types of crops. Finally, a post-processing step is performed in order to reduce the classification error caused by lower-spatial-resolution images. Experiments were carried over the so-named Campo Verde database, which consists of a set of satellite images captured by Landsat and Sentinel satellites from the municipality of Campo Verde, Brazil. In contrast to the maximum accuracy values reached by remarkable works reported in the literature (amounting to an overall accuracy of about 81%, a f1 score of 75.89%, and average accuracy of 73.35%), the proposed methodology achieves a competitive overall accuracy of 81.20%, a f1 score of 75.89%, and an average accuracy of 88.72% when classifying 10 different crops, while ensuring an adequate trade-off between the number of multiply-accumulate operations (MACs) and accuracy. Furthermore, given its ability to effectively classify patches from two image sequences, this methodology may result appealing for other real-world applications, such as the classification of urban materials.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Jian-ye Yuan ◽  
Xin-yuan Nan ◽  
Cheng-rong Li ◽  
Le-le Sun

Considering that the garbage classification is urgent, a 23-layer convolutional neural network (CNN) model is designed in this paper, with the emphasis on the real-time garbage classification, to solve the low accuracy of garbage classification and recycling and difficulty in manual recycling. Firstly, the depthwise separable convolution was used to reduce the Params of the model. Then, the attention mechanism was used to improve the accuracy of the garbage classification model. Finally, the model fine-tuning method was used to further improve the performance of the garbage classification model. Besides, we compared the model with classic image classification models including AlexNet, VGG16, and ResNet18 and lightweight classification models including MobileNetV2 and SuffleNetV2 and found that the model GAF_dense has a higher accuracy rate, fewer Params, and FLOPs. To further check the performance of the model, we tested the CIFAR-10 data set and found the accuracy rates of the model (GAF_dense) are 0.018 and 0.03 higher than ResNet18 and SufflenetV2, respectively. In the ImageNet data set, the accuracy rates of the model (GAF_dense) are 0.225 and 0.146 higher than Resnet18 and SufflenetV2, respectively. Therefore, the garbage classification model proposed in this paper is suitable for garbage classification and other classification tasks to protect the ecological environment, which can be applied to classification tasks such as environmental science, children’s education, and environmental protection.


2019 ◽  
Vol 14 (1) ◽  
pp. 124-134 ◽  
Author(s):  
Shuai Zhang ◽  
Yong Chen ◽  
Xiaoling Huang ◽  
Yishuai Cai

Online feedback is an effective way of communication between government departments and citizens. However, the daily high number of public feedbacks has increased the burden on government administrators. The deep learning method is good at automatically analyzing and extracting deep features of data, and then improving the accuracy of classification prediction. In this study, we aim to use the text classification model to achieve the automatic classification of public feedbacks to reduce the work pressure of administrator. In particular, a convolutional neural network model combined with word embedding and optimized by differential evolution algorithm is adopted. At the same time, we compared it with seven common text classification models, and the results show that the model we explored has good classification performance under different evaluation metrics, including accuracy, precision, recall, and F1-score.


2021 ◽  
Vol 16 ◽  
Author(s):  
Di Gai ◽  
Xuanjing Shen ◽  
Haipeng Chen

Background: The effective classification of the melting curve is conducive to measure the specificity of the amplified products and the influence of invalid data on subsequent experiments is excluded. Objective: In this paper, a convolutional neural network (CNN) classification model based on dynamic filter is proposed, which can categorize the number of peaks in the melting curve image and distinguish the pollution data represented by the noise peaks. Method: The main advantage of the proposed model is that it adopts the filter which changes with the input and uses the dynamic filter to capture more information in the image, making the network learning more accurate. In addition, the residual module is used to extract the characteristics of the melting curve, and the pooling operation is replaced with an atrous convolution to prevent the loss of context information. Result: In order to train the proposed model, a novel melting curve dataset is created, which includes a balanced dataset and an unbalanced dataset. The proposed method uses six classification-based assessment criteria to compare with seven representative methods based on deep learning. Experimental results show that proposed method is not only markedly outperforms the other state-of-the-art methods in accuracy, but also has much less running time. Conclusion: It evidently proves that the proposed method is suitable for judging the specificity of amplification products according to the melting curve. Simultaneously, it overcomes the difficulties of manual selection with low efficiency and artificial bias.


Author(s):  
P. Manoj Kumar ◽  
M. Parvathy ◽  
C. Abinaya Devi

Intrusion Detection Systems (IDS) is one of the important aspects of cyber security that can detect the anomalies in the network traffic. IDS are a part of Second defense line of a system that can be deployed along with other security measures such as access control, authentication mechanisms and encryption techniques to secure the systems against cyber-attacks. However, IDS suffers from the problem of handling large volume of data and in detecting zero-day attacks (new types of attacks) in a real-time traffic environment. To overcome this problem, an intelligent Deep Learning approach for Intrusion Detection is proposed based on Convolutional Neural Network (CNN-IDS). Initially, the model is trained and tested under a new real-time traffic dataset, CSE-CIC-IDS 2018 dataset. Then, the performance of CNN-IDS model is studied based on three important performance metrics namely, accuracy / training time, detection rate and false alarm rate. Finally, the experimental results are compared with those of various Deep Discriminative models including Recurrent Neural network (RNN), Deep Neural Network (DNN) etc., proposed for IDS under the same dataset. The Comparative results show that the proposed CNN-IDS model is very much suitable for modelling a classification model both in terms of binary and multi-class classification with higher detection rate, accuracy, and lower false alarm rate. The CNN-IDS model improves the accuracy of intrusion detection and provides a new research method for intrusion detection.


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