The combination of nanotechnology and traditional Chinese medicine (TCM) inspires the modernization of TCM: review on nanotechnology in TCM-based drug delivery systems

2021 ◽  
Author(s):  
Yinghao Zheng ◽  
Yun Wang ◽  
Mengyu Xia ◽  
Ya Gao ◽  
Lan Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Drug Delivery Systems ◽  
Delivery Systems

scholarly journals A review on the applications of Traditional Chinese medicine polysaccharides in drug delivery systems

2022 ◽  
Vol 17 (1) ◽  
Author(s):  
Bei Wang ◽  
Xianfeng Wang ◽  
Zhiwei Xiong ◽  
Guanzheng Lu ◽  
Weikun Ma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Drug Delivery Systems ◽  
Pharmaceutical Preparation ◽  
Structural Complexity ◽  
Delivery Systems ◽  
Low Cytotoxicity ◽  
Polysaccharide Derivatives ◽  
And Function

AbstractTraditional Chinese medicine polysaccharides (TCMPs) are plentiful and renewable resources with properties such as biocompatibility, hydrophilicity, biodegradability, and low cytotoxicity. Because the polysaccharide molecular chain contains a variety of active groups, different polysaccharide derivatives can be easily produced through chemical modification. They have been increasingly used in drug delivery systems (DDS). However, the potential of polysaccharides is usually ignored due to their structural complexity, poor stability or ambiguity of mechanisms of actions. This review summarized the applications of TCMPs in DDS around four main aspects. The general characteristics of TCMPs as drug delivery carriers, as well as the relationships between structure and function of them were summarized. Meanwhile, the direction of preparing multifunctional drug delivery materials with synergistic effect by using TCMPs was discussed. This review aims to become a reference for further research of TCMPs and their derivatives, especially applications of them as carriers in pharmaceutical preparation industry.

scholarly journals An Overview of Bioactive Natural Products-Based Nano-Drug Delivery Systems in Antitumor Chemotherapy

2021 ◽  
Vol 271 ◽  
pp. 03042
Author(s):  
Yihao Niu
Keyword(s):  
Drug Delivery ◽  
Natural Products ◽  
Chinese Medicine ◽  
Tumor Targeting ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Selective Toxicity ◽  
Bioactive Natural Products ◽  
Nano Drug Delivery ◽  
Antitumor Chemotherapy

Many bioactive natural products are derived from traditional Chinese medicine. Some of them showed good treatment potential in tumor chemotherapy. However, limited by the poorly solubility and non-selective toxicity of most of bioactive natural products, their antitumor efficacy could not be further applied in clinicals. Nano-drug delivery systems provided good platforms for bioactive natural products in antitumor treatment, and many tumor microenvironment-responsive nano-delivery carriers facilitated them to achieve more accurate tumor targeting and less toxicity, and finally improved antitumor ability of bioactive natural products.

scholarly journals Novel drug delivery systems of Chinese medicine for the treatment of inflammatory bowel disease

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Caifang Gao ◽  
Lijuan Liu ◽  
Yangyang Zhou ◽  
Zhaoxiang Bian ◽  
Shengpeng Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Inflammatory Bowel Disease ◽  
Chinese Medicine ◽  
Bowel Disease ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Inflammatory Bowel ◽  
Novel Drug

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

Dissolution rate and stability study of flavanone aglycones, naringenin and hesperetin, by drug delivery systems based on polyvinylpyrrolidone (PVP) nanodispersions

2009 ◽  
Vol 00 (00) ◽  
pp. 090810023617078-10 ◽  
Author(s):  
F. I. Kanaze ◽  
E. Kokkalou ◽  
I. Niopas ◽  
P. Barmpalexis ◽  
E. Georgarakis ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Dissolution Rate ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Stability Study
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