Internalizing RGD, a great motif for targeted peptide and protein delivery: a review article

2022 ◽  
Author(s):  
Zeinabosadat Davoodi ◽  
Fatemeh Shafiee
Keyword(s):  
Protein Delivery ◽  
Review Article

Current Approaches and Pharmaceutical Applications of Colloidosome Drug Delivery Systems

2013 ◽  
Vol 5 (4) ◽  
pp. 1832-1840
Author(s):  
S. Pradeep Kumar ◽  
Prathibha D
Keyword(s):  
Drug Delivery ◽  
Protein Delivery ◽  
Tumor Targeting ◽  
Drug Delivery Systems ◽  
Review Article ◽  
Poorly Soluble Drugs ◽  
Poorly Soluble ◽  
The Cost ◽  
The Brain ◽  
Advanced Tool

Recently a number of lipid based systems like lipospheres, liposomes, niosomes, ethosomes, and transferosomes have been developed. The purpose of this review article on colloidosome drug delivery was to compile the focus on the types, properties, fabrication techniques, characterization and stability of colloidosomes. This system also solves the problem of insolubility, instability, rapid degradation and is widely used in specialized areas like protein delivery, gene delivery, targeting to the brain and tumor targeting. In a series of vascular systems, colloidosome represents an advanced tool in drug delivery. Colloidosomes are an emerging vesicular system in drug delivery. Vesicular drug delivery reduces the cost of therapy by improved bioavailability of medication, especially in the case of poorly soluble drugs. Colloidosomes have a great encapsulation efficacy with a wide control over size, permeability, mechanical strength and compatibility.

Desiderata in connection by the calibration of the MK-system

1966 ◽  
Vol 24 ◽  
pp. 348-349
Author(s):  
Th. Schmidt-Kaler
Keyword(s):  
Absolute Magnitude ◽  
Review Article ◽  
Stellar Systems ◽  
Astronomical Data ◽  
Intrinsic Colour

This is only an informal remark about some difficulties I am worrying about.I have tried to recalibrate the MK system in terms of intrinsic colour (B–V)0and absolute magnitudeMv. The procedures used have been described in a review article by Voigt (Mitt. Astr. Ges.1963, p. 25–35), and the results for stars of the luminosity classes Ia-O,I and II have been given also in Blaauw's article on the calibration of luminosity criteria in vol. III (Basic Astronomical Data, p. 401) ofStars and Stellar Systems.

Electron-deficient boron-based catalysts for C–H bond functionalisation

2021 ◽  
Author(s):  
Yuanhong Ma ◽  
Shao-Jie Lou ◽  
Zhaomin Hou
Keyword(s):  
Review Article ◽  
Current Status ◽  
Comprehensive Overview

This review article provides a comprehensive overview to recognise the current status of electron-deficient boron-based catalysis in C–H functionalisations.

Amino-functional polyethers: versatile, stimuli-responsive polymers

2020 ◽  
Vol 11 (24) ◽  
pp. 3940-3950 ◽  
Author(s):  
Patrick Verkoyen ◽  
Holger Frey
Keyword(s):  
Ring Opening ◽  
Review Article ◽  
Stimuli Responsive ◽  
New Class ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers

Amino-functional polyethers have emerged as a new class of “smart”, i.e. pH- and thermoresponsive materials. This review article summarizes the synthesis and applications of these materials, obtained from ring-opening of suitable epoxide monomers.

Developing Evidence-Based Assessment to Prevent Over- or Underidentification of Disorders for New Language Learners

2020 ◽  
Vol 5 (4) ◽  
pp. 1026-1038
Author(s):  
Sandra Levey ◽  
Li-Rong Lilly Cheng ◽  
Diana Almodovar
Keyword(s):  
Language Learners ◽  
Grade Level ◽  
Reading Skills ◽  
Language Disorder ◽  
Academic Development ◽  
Review Article ◽  
Evidence Based ◽  
Clinical Knowledge ◽  
Language And Literacy ◽  
Support Evidence

Purpose The purpose of this review article is to present certain linguistic domains to consider in the assessment of children learning a new language. Speech-language pathologists frequently face difficulty when determining if a bilingual or multilingual child possesses a true speech or language disorder. Given the increased number of new language learners across the world, clinicians must understand differences versus disorders to prevent underidentification or overidentification of a disorder. Conclusions Early identification of a true disorder has been shown to prevent language and literacy difficulties, given that children are able to achieve grade-level reading skills when given intervention. Clinical knowledge and skills are strongly required so that children receive evidence-based assessment to support their academic development. Learning Goal Readers will gain an understanding of the factors that support evidence-based assessment of bilingual and multilingual language learners.

Treatment Considerations for Adolescents Who Exhibit Cognitive/Communication Problems: A Neuroscience Perspective

2020 ◽  
Vol 5 (6) ◽  
pp. 1767-1775
Author(s):  
Martha S. Burns
Keyword(s):  
Social Communication ◽  
Transition Period ◽  
Clinical Intervention ◽  
Review Article ◽  
Sensitive Period ◽  
Clinical Implications ◽  
Evidence Based ◽  
Communication Problems ◽  
Treatment Considerations ◽  
Behavioral Growth

Purpose Adolescence is a period of substantial neurophysiological and behavioral growth, representing a second sensitive period of brain development. It is a psychological and social transition period between childhood and adulthood with many beneficial changes occurring, especially with respect to potential responsiveness to clinical intervention. However, adolescent behavioral complexities introduce clinical challenges as well. The purpose of this review article is to review the current neuroimaging research on neurophysiological changes observed during adolescence and the cognitive and social behavioral counterparts, with specific attention to the clinical implications. The review article will then summarize currently available intervention tools that can be utilized by speech-language pathologists working with this population. It will conclude with available evidence-based social-communication approaches that may be applicable as well as available evidence-based supplemental technological cognitive interventions that may be useful in working with adolescents who exhibit language and communication issues. Conclusion As a transition period between childhood and adulthood, adolescence represents a second sensitive period during which there is opportunity for clinically derived beneficial cognitive and communication growth.

PET/CT

2005 ◽  
Vol 44 (S 01) ◽  
pp. S51-S57 ◽  
Author(s):  
T. Beyer ◽  
G. Brix
Keyword(s):  
Diagnostic Accuracy ◽  
Radiation Exposure ◽  
Dose Reduction ◽  
Pet Imaging ◽  
Clinical Studies ◽  
Review Article ◽  
Whole Body ◽  
High Radiation ◽  
Radiation Burden ◽  
Pet Ct

Summary:Clinical studies demonstrate a gain in diagnostic accuracy by employing combined PET/CT instead of separate CT and PET imaging. However, whole-body PET/CT examinations result in a comparatively high radiation burden to patients and thus require a proper justification and optimization to avoid repeated exposure or over-exposure of patients. This review article summarizes relevant data concerning radiation exposure of patients resulting from the different components of a combined PET/CT examination and presents different imaging strategies that can help to balance the diagnostic needs and the radiation protection requirements. In addition various dose reduction measures are discussed, some of which can be adopted from CT practice, while others mandate modifications to the existing hardand software of PET/CT systems.

Discriminant Analysis and its Applications in Epidemiology

1980 ◽  
Vol 19 (04) ◽  
pp. 220-226 ◽  
Author(s):  
P. A. Lachenbruch ◽  
W. R. Clarke
Keyword(s):  
Discriminant Analysis ◽  
Historical Review ◽  
Review Article ◽  
Logistic Discrimination

This review article discusses current use of discriminant analysis in epidemiology. Contents include historical review, simple extensions and generalizations, examples, evaluation of rules, logistic discrimination, and robustness.

GUL-E- SURKH (Rosa damascena Mill.) AND ITS THERAPEUTIC USES DESCRIBED IN UNANI LITERATURE

2018 ◽  
Vol 4 (1) ◽  
pp. 411-414
Author(s):  
Nazamuddin Md ◽  
Wadud Abdul ◽  
Najeeb Jahan ◽  
Tanwir Alam M ◽  
Asim Mohammad Khan ◽  
...  
Keyword(s):  
Therapeutic Indication ◽  
Review Article ◽  
Rosa Damascena ◽  
Ibn Sina ◽  
Rose Flower ◽  
Therapeutic Uses

Gul-e-Surkh (Rose flower) is the Persian name for the Rosa damascena Mill. In Unani system of medicine Rose flower is used for medicinal purposes. Ibn Sina considers Gul-e- Surkh as one of the best drug for liver. Rose flower in various doses form and/or in combination with many other drugs are indicated in various disease. It is commonly being used as general tonic for Lungs, Stomach, Intestine, Liver, Rectum, Kidney, Heart, and Uterus. Fresh flowers are purgative and dried one is astringent in properties. In this review article authors try to encompass the therapeutic indication of Rosa damascena Mill described in Unani literature.

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