Electron-deficient boron-based catalysts for C–H bond functionalisation

2021 ◽  
Author(s):  
Yuanhong Ma ◽  
Shao-Jie Lou ◽  
Zhaomin Hou
Keyword(s):  
Review Article ◽  
Current Status ◽  
Comprehensive Overview

This review article provides a comprehensive overview to recognise the current status of electron-deficient boron-based catalysis in C–H functionalisations.

A Critical Review on 3D-printed Dosage Forms

2019 ◽  
Vol 24 (42) ◽  
pp. 4957-4978 ◽  
Author(s):  
Ilias El Aita ◽  
Hanna Ponsar ◽  
Julian Quodbach
Keyword(s):  
3D Printing ◽  
Drug Release ◽  
Critical Evaluation ◽  
Dosage Forms ◽  
Review Article ◽  
Current Status ◽  
Comprehensive Overview ◽  
Pharmaceutical Dosage Forms ◽  
Advantages And Disadvantages ◽  
Pharmaceutical Application

Background: In the last decades, 3D-printing has been investigated and used intensively in the field of tissue engineering, automotive and aerospace. With the first FDA approved printed medicinal product in 2015, the research on 3D-printing for pharmaceutical application has attracted the attention of pharmaceutical scientists. Due to its potential of fabricating complex structures and geometrics, it is a highly promising technology for manufacturing individualized dosage forms. In addition, it enables the fabrication of dosage forms with tailored drug release profiles. Objective: The aim of this review article is to give a comprehensive overview of the used 3D-printing techniques for pharmaceutical applications, including information about the required material, advantages and disadvantages of the respective technique. Methods: For the literature research, relevant keywords were identified and the literature was then thoroughly researched. Conclusion: The current status of 3D-printing as a manufacturing process for pharmaceutical dosage forms was highlighted in this review article. Moreover, this article presents a critical evaluation of 3D-printing to control the dose and drug release of printed dosage forms.

Recent Developments in the Downstream Processing of Phycobiliproteins from Algae: A Review

2021 ◽  
Vol 06 ◽  
Author(s):  
Ayekpam Chandralekha Devi ◽  
G. K. Hamsavi ◽  
Simran Sahota ◽  
Rochak Mittal ◽  
Hrishikesh A. Tavanandi ◽  
...  
Keyword(s):  
Cell Wall ◽  
Large Scale ◽  
Downstream Processing ◽  
Review Article ◽  
Current Status ◽  
Wall Structure ◽  
Scale Production ◽  
Cell Wall Disruption ◽  
Recent Developments ◽  
Macro Algae

Abstract: Algae (both micro and macro) have gained huge attention in the recent past for their high commercial value products. They are the source of various biomolecules of commercial applications ranging from nutraceuticals to fuels. Phycobiliproteins are one such high value low volume compounds which are mainly obtained from micro and macro algae. In order to tap the bioresource, a significant amount of work has been carried out for large scale production of algal biomass. However, work on downstream processing aspects of phycobiliproteins (PBPs) from algae is scarce, especially in case of macroalgae. There are several difficulties in cell wall disruption of both micro and macro algae because of their cell wall structure and compositions. At the same time, there are several challenges in the purification of phycobiliproteins. The current review article focuses on the recent developments in downstream processing of phycobiliproteins (mainly phycocyanins and phycoerythrins) from micro and macroalgae. The current status, the recent advancements and potential technologies (that are under development) are summarised in this review article besides providing future directions for the present research area.

scholarly journals Narrative review of EHDI in South Africa

2015 ◽  
Vol 62 (1) ◽  
Author(s):  
Selvarani Moodley ◽  
Claudine Storbeck
Keyword(s):  
South Africa ◽  
Hearing Loss ◽  
Hearing Screening ◽  
Narrative Review ◽  
Current Status ◽  
Western Cape ◽  
Comprehensive Overview ◽  
National Priority ◽  
Newborn Hearing ◽  
Made In

Background: With 17 babies born with hearing loss every day in South Africa, there is a pressing need for systematic Early Hearing Detection and Intervention (EHDI) services. Progress is being made in offering newborn hearing screening and studies have been conducted to document these processes within South Africa. However, due to the lack of a national and holistic overview of EHDI services to date, an accurate picture of the current status of EHDI within the South African context is required. Objective: To document and profile what has been published within the field of EHDI in South Africa over the last two decades (Jan 1995–Sept 2014) in order to gain a comprehensive overview of the current status and practice of screening and diagnosis in the field of paediatric hearing loss. Method: A narrative review of peer-reviewed articles related to EHDI in South Africa was conducted by searching the EBSCOHOST, SCOPUS and JSTOR databases for the period January 1995 to September 2014. Results: Results indicate that over the last two decades research and publications in the field of EHDI have increased considerably. These publications have revealed extensive knowledge related to paediatric hearing screening and intervention services in South Africa; however, this knowledge seems to be limited primarily to the provinces of Gauteng and the Western Cape. Furthermore, studies pertaining to diagnosis have revealed that, although much has been written on the scientific aspects on tools for diagnosis of hearing loss, there is a lack of comprehensive information on diagnostic protocols and procedures. Conclusion: Despite the clear progress being made in South Africa in the field of early hearing detection and intervention, there is a need for comprehensive studies on protocols and procedures in diagnosing paediatric hearing loss. Finally, the narrative review revealed a clear need to ensure that development and growth in the field of EHDI is a national priority and extends beyond the two provinces currently showing growth.

scholarly journals Recovery rates, enhanced oil recovery and technological limits

2014 ◽  
Vol 372 (2006) ◽  
pp. 20120320 ◽  
Author(s):  
Ann Muggeridge ◽  
Andrew Cockin ◽  
Kevin Webb ◽  
Harry Frampton ◽  
Ian Collins ◽  
...  
Keyword(s):  
Enhanced Oil Recovery ◽  
Oil Recovery ◽  
Current Status ◽  
Comprehensive Overview ◽  
Oil Reserves ◽  
The North ◽  
History Of ◽  
The North Sea ◽  
Giant Fields ◽  
Broad Consensus

Enhanced oil recovery (EOR) techniques can significantly extend global oil reserves once oil prices are high enough to make these techniques economic. Given a broad consensus that we have entered a period of supply constraints, operators can at last plan on the assumption that the oil price is likely to remain relatively high. This, coupled with the realization that new giant fields are becoming increasingly difficult to find, is creating the conditions for extensive deployment of EOR. This paper provides a comprehensive overview of the nature, status and prospects for EOR technologies. It explains why the average oil recovery factor worldwide is only between 20% and 40%, describes the factors that contribute to these low recoveries and indicates which of those factors EOR techniques can affect. The paper then summarizes the breadth of EOR processes, the history of their application and their current status. It introduces two new EOR technologies that are beginning to be deployed and which look set to enter mainstream application. Examples of existing EOR projects in the mature oil province of the North Sea are discussed. It concludes by summarizing the future opportunities for the development and deployment of EOR.

scholarly journals Advances in Corrosion-Resistant Thermal Spray Coatings for Renewable Energy Power Plants: Part II—Effect of Environment and Outlook

2019 ◽  
Vol 28 (8) ◽  
pp. 1789-1850 ◽  
Author(s):  
Esmaeil Sadeghi ◽  
Nicolaie Markocsan ◽  
Shrikant Joshi
Keyword(s):  
High Temperature ◽  
Thermal Spray ◽  
Power Plants ◽  
High Temperature Corrosion ◽  
Thermal Spray Coatings ◽  
Current Status ◽  
Comprehensive Overview ◽  
Biomass Waste ◽  
Corrosion Resistant ◽  
Spray Coatings

Abstract High-temperature corrosion of critical components such as water walls and superheater tubes in biomass/waste-fired boilers is a major challenge. A dense and defect-free thermal spray coating has been shown to be promising to achieve a high electrical/thermal efficiency in power plants. The field of thermal spraying and quality of coatings have been progressively evolving; therefore, a critical assessment of our understanding of the efficacy of coatings in increasingly aggressive operating environments of the power plants can be highly educative. The effects of composition and microstructure on high-temperature corrosion behavior of the coatings were discussed in the first part of the review. The present paper that is the second part of the review covers the emerging research field of performance assessment of thermal spray coatings in harsh corrosion-prone environments and provides a comprehensive overview of the underlying high-temperature corrosion mechanisms that lead to the damage of exposed coatings. The application of contemporary analytical methods for better understanding of the behavior of corrosion-resistant coatings is also discussed. A discussion based on an exhaustive review of the literature provides an unbiased commentary on the advanced accomplishments and some outstanding issues in the field that warrant further research. An assessment of the current status of the field, the gaps in the scientific understanding, and the research needs for the expansion of thermal spray coatings for high-temperature corrosion applications is also provided.

scholarly journals Current status of therapeutic approaches and vaccines for SARS-CoV-2

2021 ◽  
Author(s):  
Braira Wahid ◽  
Anam Amir ◽  
Ayesha Ameen ◽  
Muhammad Idrees
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Review Article ◽  
Experimental Designs ◽  
Current Status ◽  
Therapeutic Approaches ◽  
Efficacious Treatment ◽  
Rapid Pace ◽  
Global Health Challenge

SARS-CoV-2, declared a pandemic in March 2020, is the current global health challenge. The global bioburden of this virus is increasing at a rapid pace. Many antiviral drugs and vaccines have been registered for clinical trials because of their inhibitory activity observed in vitro. Currently, five types of vaccines have successfully passed Phase IV clinical trial and are being administered in populations worldwide. A plethora of experimental designs have been proposed worldwide in order to find a safe and efficacious treatment option. Therefore, it is necessary to provide baseline data and information to clinicians and researchers so that they can review the current status of therapeutics and efficacy of already developed vaccines. This review article summarizes all therapeutic options that may help to combat SARS-CoV-2.

scholarly journals Adipose-Derived Stem Cells: Current Applications and Future Directions in the Regeneration of Multiple Tissues

2020 ◽  
Vol 2020 ◽  
pp. 1-26
Author(s):  
Jiaxin Zhang ◽  
Yuzhe Liu ◽  
Yutong Chen ◽  
Lei Yuan ◽  
He Liu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Skin Wound ◽  
Current Status ◽  
Therapeutic Effects ◽  
Adipose Derived Stem Cells ◽  
Isolation And Identification ◽  
Comprehensive Overview ◽  
Skin Wound Healing ◽  
Paracrine Factors ◽  
Future Directions

Adipose-derived stem cells (ADSCs) can maintain self-renewal and enhanced multidifferentiation potential through the release of a variety of paracrine factors and extracellular vesicles, allowing them to repair damaged organs and tissues. Consequently, considerable attention has increasingly been paid to their application in tissue engineering and organ regeneration. Here, we provide a comprehensive overview of the current status of ADSC preparation, including harvesting, isolation, and identification. The advances in preclinical and clinical evidence-based ADSC therapy for bone, cartilage, myocardium, liver, and nervous system regeneration as well as skin wound healing are also summarized. Notably, the perspectives, potential challenges, and future directions for ADSC-related researches are discussed. We hope that this review can provide comprehensive and standardized guidelines for the safe and effective application of ADSCs to achieve predictable and desired therapeutic effects.

Rational nanostructure design of graphitic carbon nitride for photocatalytic applications

2019 ◽  
Vol 7 (19) ◽  
pp. 11584-11612 ◽  
Author(s):  
Na Tian ◽  
Hongwei Huang ◽  
Xin Du ◽  
Fan Dong ◽  
Yihe Zhang
Keyword(s):  
Carbon Nitride ◽  
Review Article ◽  
Graphitic Carbon ◽  
Graphitic Carbon Nitride ◽  
Comprehensive Overview ◽  
Photocatalytic Applications

This review article provides a comprehensive overview of the nanostructure design of g-C3N4 with various dimensional structures and promising applications.

scholarly journals Geographic Object-Based Image Analysis: A Primer and Future Directions

2020 ◽  
Vol 12 (12) ◽  
pp. 2012 ◽  
Author(s):  
Maja Kucharczyk ◽  
Geoffrey J. Hay ◽  
Salar Ghaffarian ◽  
Chris H. Hugenholtz
Keyword(s):  
Image Analysis ◽  
Current Status ◽  
Future Research ◽  
Deep Convolutional Neural Networks ◽  
Comprehensive Overview ◽  
Image Objects ◽  
Object Based Image Analysis ◽  
Object Based ◽  
Geographic Object ◽  
Methodological Considerations

Geographic object-based image analysis (GEOBIA) is a remote sensing image analysis paradigm that defines and examines image-objects: groups of neighboring pixels that represent real-world geographic objects. Recent reviews have examined methodological considerations and highlighted how GEOBIA improves upon the 30+ year pixel-based approach, particularly for H-resolution imagery. However, the literature also exposes an opportunity to improve guidance on the application of GEOBIA for novice practitioners. In this paper, we describe the theoretical foundations of GEOBIA and provide a comprehensive overview of the methodological workflow, including: (i) software-specific approaches (open-source and commercial); (ii) best practices informed by research; and (iii) the current status of methodological research. Building on this foundation, we then review recent research on the convergence of GEOBIA with deep convolutional neural networks, which we suggest is a new form of GEOBIA. Specifically, we discuss general integrative approaches and offer recommendations for future research. Overall, this paper describes the past, present, and anticipated future of GEOBIA in a novice-accessible format, while providing innovation and depth to experienced practitioners.

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