scholarly journals Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana

2021 ◽  
Author(s):  
Han Wu ◽  
Hui-Xiang Yang ◽  
Zheng-Hui Li ◽  
Tao Feng ◽  
Ji-Kai Liu
Keyword(s):  
Antibacterial Activity ◽  
Spectroscopic Methods

Abstract Five previously undescribed guanacastane diterpenoids, namely psathyrellins A–E (1–5), were obtained from cultures of the mushroom Psathyrella candolleana. Their structures with absolute configurations were elucidated by extensive spectroscopic methods. Compounds 1–3 showed antibacterial activity against four strains with MIC values in a range of 16–128 μg/mL. Graphic Abstract

scholarly journals A New Prenylated Flavanoid with Antibacterial Activity from Propolis Collected in Egypt

2010 ◽  
Vol 5 (1) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Ashraf El-Bassuony ◽  
Sameh AbouZid
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacillus Cereus ◽  
Spectroscopic Methods ◽  
Gram Positive ◽  
Gram Negative

A novel prenylated flavanoid, isonymphaeol-D (1), together with two known compounds, isonymphaeol-B (2) and nymphaeol-B (3), were isolated from Egyptian propolis. The structures of the isolated compounds were determined by various spectroscopic methods. 1 exhibited antibacterial activity against Gram-positive (Bacillus cereus, Staphylococcus aureus) and Gram-negative strains (Serratia sp., Pseudomonos sp., Escherichia coli).

Epoxide Sesquiterpenes and Steroids from Cremanthodium discoideum

2000 ◽  
Vol 53 (10) ◽  
pp. 831 ◽  
Author(s):  
Ying Zhu ◽  
Qi Xiu Zhu ◽  
Zhong Jian Jia
Keyword(s):  
Antibacterial Activity ◽  
Tumour Cell ◽  
Leukemia Cell ◽  
Promyelocytic Leukemia ◽  
Spectroscopic Methods ◽  
Significant Activity ◽  
Two Dimensional ◽  
Human Promyelocytic Leukemia Cell ◽  
Tumour Cell Lines ◽  
Whole Plants

Two new epoxide bisabolane sesquiterpenes and a new steroid were isolated from the whole plants of Cremanthodium discoideum Maxim. Their structures have been established by spectroscopic methods including two-dimensional n.m.r. (1H–1H COSY, 1H–1H NOESY, HMBC, HMQC) techniques. Six known steroids were also isolated and characterized. Compound (1) has antibacterial activity against Bacillus aeruginosus and B. subtilis. Two sesquiterpenes showed significant activity against two tumour cell lines: human promyelocytic leukemia cell HL-60 and human hapatoma cell SMMC-7721.

Nitric Oxide Inhibitory Activity of Xanthones from the Green Fruits of Cratoxylum formosum ssp. pruniflorum

2010 ◽  
Vol 63 (11) ◽  
pp. 1550 ◽  
Author(s):  
Nawong Boonnak ◽  
Achjana Khamthip ◽  
Chatchanok Karalai ◽  
Suchada Chantrapromma ◽  
Chanita Ponglimanont ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Antibacterial Activity ◽  
Inhibitory Activity ◽  
Spectroscopic Methods ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
X Ray ◽  
X Ray Crystallography ◽  
Ic50 Values ◽  
Mic Value

Three new xanthones, pruniflorone M-O (1–3), and a new xanthonolignoid, 3-methoxy-5′-demethoxycadensin G (4), were isolated from the green fruits of Cratoxylum formosum ssp. pruniflorum along with three known xanthones (5–7) and a known flavonoid (8). Their structures were elucidated by spectroscopic methods and the structure of 1 was also determined by X-ray crystallography. Compounds 2 and 7 showed potent nitric oxide inhibitory activity with IC50 values of 4.4 and 4.3 μM, respectively. Moreover, 7 also showed strong antibacterial activity against both Gram-positive and Gram-negative bacteria with an MIC value of 4.67 μg mL–1.

scholarly journals Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a

2015 ◽  
Vol 51 (4) ◽  
pp. 861-867 ◽  
Author(s):  
Roosevelt Albuquerque Gomes ◽  
Yanna Carolina Ferreira Teles ◽  
Fillipe de Oliveira Pereira ◽  
Luis Alberto de Sousa Rodrigues ◽  
Edeltrudes de Oliveira Lima ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Chemical Compounds ◽  
Structural Identification ◽  
2D Nmr ◽  
Spectroscopic Methods ◽  
Phytochemical Study ◽  
Pheophytin A ◽  
Chromatographic Techniques

abstract Sidastrum micranthum (A. St.-Hil.) Fryxell, a member of the Malvaceae family, is called malva preta in Brazil. As this species is commonly used to treat bronchitis, cough, and asthma, better knowledge of its chemical compounds is important. The phytochemical study of its hexane extract, using chromatographic techniques, led to isolation of six compounds: the triterpene isoarborinol, a mixture of sitosterol and stigmasterol, sitosterol-3-O-β-D-glucopyranoside, pheophytin a, and 132-hydroxy-(132-S)-pheophytin a. Structural identification of these compounds was carried out using spectroscopic methods such as IR and 1D and 2D NMR (HOMOCOSY, HMQC, HMBC, and NOESY). Compounds isolated from S. micranthum were screened for their in vitro antifungal and antibacterial activity against twenty fungal and bacterial standard strains. Pheophytin a exhibited antimicrobial action against all microorganisms tested.

A New Inhibitor of Synovial Phospholipase A2 from Fermentations of Penicillium Sp. 62-92

1998 ◽  
Vol 53 (1-2) ◽  
pp. 60-64 ◽  
Author(s):  
Ludwig Witter ◽  
Timm Anke ◽  
Olov Sterner
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Cytotoxic Activities ◽  
Spectroscopic Methods ◽  
Submerged Cultures ◽  
Amide Bonds ◽  
Penicillium Sp ◽  
L1210 Cells ◽  
Hela S3 ◽  
Weak Antibacterial Activity

AbstractPenidiamide, a new tripetide containing dehydrotryptamine, glycine and anthranilic acid linked together by two amide bonds, and oxindole were isolated from submerged cultures of Penicillium sp. 62-92 . Both compounds preferentially inhibited human synovial phospholipase A2, penidiamide with an IC50 of 30 μᴍ and oxindole of 380 μᴍ. With the exception of U 937 cells (leukemia, human), no cytotoxic activities were detected against HL-60- (leukemia, human), HeLa S3- (epitheloid carcinoma, human), BHK 21- (kidney fibroblasts, hamster), and L1210-cells (leukemia, mouse). No antimicrobial activity was detected for oxindole, and only weak antibacterial activity for penidiamide. The structure of penidiamide was elucidated by spectroscopic methods.

Quinonoids from the barks of Cratoxylum formosum subsp.pruniflorum

2007 ◽  
Vol 85 (5) ◽  
pp. 341-345 ◽  
Author(s):  
Nawong Boonnak ◽  
Chatchanok Karalai ◽  
Suchada Chantrapromma ◽  
Chanita Ponglimanont ◽  
Akkharawit Kanjana-Opas ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Cytotoxic Activities ◽  
Spectroscopic Methods

A mixture of new bianthrones J (1a and 1b) was isolated from the barks of Cratoxylum formosum subsp. pruniflorum together with six known quinonoids, namely bianthrone A1 (2), vismones E (3) and D (4), 11-hydroxy-5-methoxy-2,2,9-trimethyl-2H-anthra[1,2-b]-pyran-7,12-dione (5), vismiaquinone (6), and 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone (7). Their structures were assigned on the basis of spectroscopic methods. The antibacterial and cytotoxic activities of compounds 3 and 4 were also reported.Key words: Cratoxylum formosum subsp. pruniflorum, bianthrone, vismone, anthraquinone, antibacterial activity, cytotoxicity.

scholarly journals Mixed-Ligand Nickel(II) Complexes Containing Sulfathiazole and Cephalosporin Antibiotics: Synthesis, Characterization, and Antibacterial Activity

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
J. R. Anacona ◽  
Maried Lopez
Keyword(s):  
Antibacterial Activity ◽  
Organic Solvents ◽  
Chelating Agents ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Spectroscopic Methods ◽  
Lactam Carbonyl ◽  
Cephalosporin Antibiotics ◽  
Polymeric Structures

Nickel(II) reacts with cephalosporins plus sulfathiazole (Hstz) to form the following mixed-ligand complexes of general formulae [Ni(L)(stz)(H2O)x]n (L1,4, x=1; L2,3, x=0; L = monoanion of cefazolin HL1, cephalothin HL2, cefotaxime HL3, ceftriaxone HL4) and [Ni(L5)(stz)]Cl (cefepime L5), which were characterized by physicochemical and spectroscopic methods. Their spectra indicated that cephalosporins are acting as multidentate chelating agents, via the lactam carbonyl and carboxylate and N-azomoieties. The complexes are insoluble in water and common organic solvents but soluble in DMSO, where the [Ni(L5)(stz)]Cl complex is 1 : 1 electrolyte. They probably have polymeric structures. They have been screened for antibacterial activity, and the results are compared with the activity of commercial cephalosporins.

scholarly journals Synthesis and characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with 3-salicylidenehydrazono-2-indolinone

2003 ◽  
Vol 68 (8-9) ◽  
pp. 641-647 ◽  
Author(s):  
Sandra Konstantinovic ◽  
Blaga Radovanovic ◽  
Zivojin Cakic ◽  
Vesna Vasic
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Molar Conductivity ◽  
Spectral Studies ◽  
Synthesis And Characterization ◽  
Planar Geometry ◽  
Spectroscopic Methods ◽  
Square Planar

Complexes of Co(II), Ni(II), Cu(II) and Zn(II) with 3-salicylidenehydrazono-2-indolinone were prepared. Their structure was established to be [MLCl].Cl by using elemental analysis and molar conductivity, as well as AA, FTIR, UV/VIS and 1H-NMR spectroscopic methods. The spectral studies indicated a square-planar geometry for the Ni(II) and Cu(II) complexes and a tetrahedral one for the Co(II) and Zn(II) complexes. The complexes were tested for antibacterial activity against Staphylococcus aureus, Enterococcus D, Proteus mirabilis, Escherichia coli, Bacillus anthracis, Pseudomonas aeruginosa and Candida albicans.

scholarly journals Antibacterial and Cytotoxic Limonoids from the Seeds of Swietenia mahagony

1970 ◽  
Vol 8 (2) ◽  
pp. 141-145
Author(s):  
Md Abdul Kader ◽  
Md Ekramul Haque ◽  
Proma Khondkar ◽  
Md Monirul Islam ◽  
M Mukhlesur Rahman
Keyword(s):  
Antibacterial Activity ◽  
Brine Shrimp ◽  
Soluble Fraction ◽  
Ethanolic Extract ◽  
2D Nmr ◽  
Chloroform Extract ◽  
Spectroscopic Methods ◽  
Gram Negative Bacteria ◽  
2D Nmr Spectroscopy ◽  
Gram Negative

Two limonoids, swietenine (1) and 3-O-tigloylswietenolide (2), were isolated from the chloroform soluble fraction of an ethanolic extract of Swietenia mahagony seed. The structures of these compounds were confirmed by spectroscopic methods, including both 1D and 2D NMR spectroscopy. The chloroform extract and the limonoids (1 and 2) exhibited moderate antibacterial activity against a series of Gram positive and Gram negative bacteria. The minimum inhibitory concentrations (MICs) of 1 and 2 were found to be in the range of 32-64 μg/ml against Bacillus megatorium and Escherichia coli. Compounds 1 and 2 were also assessed for preliminary cytotoxicity against brine shrimp and the LC50 values were found to be 14.6 and 12.5 μg/ml, respectively. Key words: Swietenia mahagony; Meliaceae; Limonoids; Swietenine; 3-tigloylswietenolide; Antibacterial activity; Cytotoxicity. DOI: 10.3329/dujps.v8i2.6028 Dhaka Univ. J. Pharm. Sci. 8(2): 141-145, 2009 (December)

Antibacterial Ellagic Acid Derivatives and Other Constituents from Pancovia pedicellaris

2009 ◽  
Vol 64 (9) ◽  
pp. 1070-1076 ◽  
Author(s):  
René F. Soh ◽  
Jean K. Bankeu ◽  
Bruno N. Lenta ◽  
Brice M. Mbáning ◽  
Silvère Ngouela ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antibacterial Activity ◽  
Bacillus Subtilis ◽  
Ellagic Acid ◽  
Micrococcus Luteus ◽  
Spectroscopic Methods ◽  
Ellagic Acid Derivatives ◽  
Reported Data ◽  
Antibacterial Potential

Two new ellagic acid derivatives, named panconosides A (1) andB(2) were isolated from Pancovia pedicellaris together with eleven known compounds (3 - 13). The structures of 1 and 2, as well as those of the known compounds were established by spectroscopic methods and by comparison with previously reported data. Compounds 1 and 2 were tested in vitro for their antibacterial potential against six strains of microorganisms: Micrococcus luteus, Streptococcus ferus, Streptococcus minor, Escherichia coli, Bacillus subtilis, and Pseudomonas agarici. They were found to exhibit moderate antibacterial activity against all the tested strains compared to standard drugs.

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