Role of Maternal Nutrition on Gestational Age and Birth Weight

Background: Platelets play an important role in the formation of pulmonary blood vessels, and thrombocytopenia is common in patients with pulmonary diseases. However, a few studies have reported on the role of platelets in bronchopulmonary dysplasia.Objective: The objective of the study was to explore the relationship between platelet metabolism and bronchopulmonary dysplasia in premature infants.Methods: A prospective case-control study was performed in a cohort of premature infants (born with a gestational age <32 weeks and a birth weight <1,500 g) from June 1, 2017 to June 1, 2018. Subjects were stratified into two groups according to the diagnostic of bronchopulmonary dysplasia: with bronchopulmonary dysplasia (BPD group) and without bronchopulmonary dysplasia (control group). Platelet count, circulating megakaryocyte count (MK), platelet-activating markers (CD62P and CD63), and thrombopoietin (TPO) were recorded and compared in two groups 28 days after birth; then serial thrombopoietin levels and concomitant platelet counts were measured in infants with BPD.Results: A total of 252 premature infants were included in this study. Forty-eight premature infants developed BPD, 48 premature infants without BPD in the control group who were matched against the study infants for gestational age, birth weight, and admission diagnosis at the age of postnatal day 28. Compared with the controls, infants with BPD had significantly lower peripheral platelet count [BPD vs. controls: 180.3 (24.2) × 109/L vs. 345.6 (28.5) × 109/L, p = 0.001]. Circulating MK count in the BPD group was significantly more abundant than that in the control group [BPD vs. controls: 30.7 (4.5)/ml vs. 13.3 (2.6)/ml, p = 0.025]. The level of CD62p, CD63, and TPO in BPD group was significantly higher than the control group [29.7 (3.1%) vs. 14.5 (2.5%), 15.4 (2.0%) vs. 5.8 (1.7%), 301.4 (25.9) pg/ml vs. 120.4 (14.2) pg/ml, all p < 0.05]. Furthermore, the concentration of TPO was negatively correlated with platelet count in BPD group with thrombocytopenia.Conclusions: Our findings suggest that platelet metabolism is involved in the development of BPD in preterm infants. The possible mechanism might be through increased platelet activation and promoted TPO production by feedback.

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Determinants of low birth weight and its relationship with stunted toddler status in Magelang Regency, Indonesia

E3S Web of Conferences ◽

10.1051/e3sconf/202132506004 ◽

2021 ◽

Vol 325 ◽

pp. 06004

Author(s):

Sri Rum Giyarsih ◽

Ratih Fitria Putri ◽

Agustinur Saputri ◽

Esti Nugraheni ◽

Nia Setiyawati

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Health Behavior ◽

Gestational Age ◽

Maternal Age ◽

Maternal Nutrition ◽

Binary Logistic Regression ◽

Primary Data ◽

Nutritional Knowledge ◽

Age At Birth

Stunting contributes to a decrease in the quality of life. One of the potential factors which causes stunting is low birth weight (LBW). The objectives of this study are (1) to obtain representations of the characteristics of mothers and stunted toddlers; (2) to analyze the influence of maternal age at birth, gestational age, maternal hygiene and health behavior, and maternal nutrition knowledge related to LBW; and (3) to identify the relationship between LBW and stunted toddlers in Magelang Regency. This study used a mix-method approach that combined primary data and in-depth interviews. The binary logistic regression results found that maternal age at birth, gestational age, maternal hygiene and health behavior, and maternal nutritional knowledge had a significant effect to LBW on stunted toddlers.

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The Association between Birth Weight and Gestational Age and Asthma in 6-7- and 13-14-Year-Old Children

Scientifica ◽

10.1155/2016/3987460 ◽

2016 ◽

Vol 2016 ◽

pp. 1-10 ◽

Cited By ~ 1

Author(s):

Zamani Raheleh ◽

Alikhani Ahmad ◽

Heydarzadeh Abtin ◽

Zare Roghaye ◽

Hashemain Sara ◽

...

Keyword(s):

Birth Weight ◽

Severe Asthma ◽

Gestational Age ◽

Lower Risk ◽

Age Groups ◽

Age Group ◽

Group 13 ◽

Increased Risk ◽

Group 6

Background. Previous studies that assessed the role of birth weight and gestational age in the risk of asthma have been conflicting.Objectives. To examine the association between birth weight and gestational age and symptoms of asthma.Patients and Methods. Subjects were 6656 school children of ages 6-7 and 13-14 years from urban districts of Mazandaran, Iran. ISAAC questionnaires were used.Results. There was an increased risk of “wheeze ever” in both age groups with birth weight under 2.5 kg and in all subgroups of low birth weight (LBW). Birth weight more than 3.5 kg was associated with lower risk of “severe asthma” in age group 6-7 years. With respect to gestational age, higher risks of “wheeze ever,” “asthma ever,” and “night cough in the past 12 months” were found in age group 13-14 years born before 37 weeks and the risk of “severe asthma” was higher in younger group (6-7 years). A lower risk of "asthma ever" was also found in 6-7-year-old children and 13-14-year-old girls who were born after 40 weeks.Conclusions. This study showed that there is a direct relation between “wheeze ever” and LBW and an inverse relation between risk of “severe asthma” and birth weight more than 3.5 kg.

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THE ROLE OF MONOAMINES IN REGULATION OF ANGIOGENESIS AND PROSPECTS OF THEIR APPLICATION IN RETINOPATHY OF PREMATURITY

Russian Pediatric Ophthalmology ◽

10.18821/1993-1859-2018-13-2-76-80 ◽

2018 ◽

Vol 13 (2) ◽

pp. 76-80

Author(s):

L. A Katargina ◽

E. V Denisova ◽

N. A Osipova ◽

Anna Y. Panova

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Visual Impairment ◽

Gestational Age ◽

Retinopathy Of Prematurity ◽

Treatment Guidelines ◽

Relevant Literature ◽

Pathogenetic Role ◽

Medline Database

Retinopathy of prematurity is the main cause of visual impairment and blindness in infants with low birth weight and preterm gestational age, in spite of the achievements in neonatology and wide applying of diagnostic and treatment guidelines. The pathogenetic role of VEGF is determined in course of normal angiogenesis and in retinopathy of prematurity. Scientists continue the search of another significant vasoprolifirative factors and methods how to inhibit them. This review is devoted to monoamines’ role in angiogenesis. The search for the relevant literature was carried out using the Medline database.

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Role of Morphometry of Placenta in Determination of Birth Weight of Fetus in Hypertensive Mothers

Academia Anatomica International ◽

10.21276/aanat.2020.6.2.17 ◽

2020 ◽

Vol 6 (2) ◽

pp. 77-80

Author(s):

Yousuf Begum ◽

Syeda Ayesha Fatima ◽

Syeda Khadija Fatima

Keyword(s):

Birth Weight ◽

Surface Area ◽

Gestational Age ◽

Transverse Diameter ◽

Pregnancy Induced Hypertension ◽

Uncomplicated Pregnancy ◽

Induced Hypertension ◽

The Mean

Background: The present study was conducted to assess the association of morphometry of the placenta and birth weight of fetus in hypertensive mothers. Subjects and Methods: The present study was conducted on 74 pregnant women with an uncomplicated pregnancy and those with pregnancy-induced hypertension (PIH). The following morphometric parameters of each placenta were recorded: weight, volume, thickness, transverse diameter, and shape. Gestational age of mothers, sex and birth weight of newborns were recorded. Results: The majority of male babies with weight > 2500 grams had > 37 weeks of gestational age and the majority of female babies with weight >2500 grams had >37 weeks of gestational age. The mean weight of placentae in male babies was 416.7 grams, the mean surface area was 226.5 sq cm, mean volume was 372.2 ml and mean thickness were 2.04 cm. while the mean weight of placentae in female babies was 407.5 grams, the mean surface area was 220.4 sq cm, mean volume was 354.6 ml and mean thickness was 2.10 cm. Statistics show that the highest sensitivity and specificity for determining the low birth weight of babies in hypertensive mothers was seen with a surface area of the placenta which was 82.3% and 75.6% respectively. The positive predictive value for the weight of the placenta was 65.4%, for the surface area it was 67.8% and for the volume of the placenta, it was 64.2%. Conclusion: To conclude, it was found that placental morphometry like weight, surface area, volume and sex of the baby determined the birth weight efficiently in hypertensive mothers.

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