scholarly journals Linguistic feature of anorexia nervosa: a prospective case–control pilot study

Author(s):  
Vittoria Cuteri ◽  
Giulia Minori ◽  
Gloria Gagliardi ◽  
Fabio Tamburini ◽  
Elisabetta Malaspina ◽  
...  

Abstract Purpose Attention has recently been paid to Clinical Linguistics for the detection and support of clinical conditions. Many works have been published on the “linguistic profile” of various clinical populations, but very few papers have been devoted to linguistic changes in patients with eating disorders. Patients with Anorexia Nervosa (AN) share similar psychological features such as disturbances in self-perceived body image, inflexible and obsessive thinking and anxious or depressive traits. We hypothesize that these characteristics can result in altered linguistic patterns and be detected using the Natural Language Processing tools. Methods We enrolled 51 young participants from December 2019 to February 2020 (age range: 14–18): 17 girls with a clinical diagnosis of AN, and 34 normal-weighted peers, matched by gender, age and educational level. Participants in each group were asked to produce three written texts (around 10–15 lines long). A rich set of linguistic features was extracted from the text samples and the statistical significance in pinpointing the pathological process was measured. Results Comparison between the two groups showed several linguistics indexes as statistically significant, with syntactic reduction as the most relevant trait of AN productions. In particular, the following features emerge as statistically significant in distinguishing AN girls and their normal-weighted peers: the length of the sentences, the complexity of the noun phrase, and the global syntactic complexity. This peculiar pattern of linguistic erosion may be due to the severe metabolic impairment also affecting the central nervous system in AN. Conclusion These preliminary data showed the existence of linguistic parameters as probable linguistic markers of AN. However, the analysis of a bigger cohort, still ongoing, is needed to consolidate this assumption. Level of evidence III Evidence obtained from case–control analytic studies.

2021 ◽  
Author(s):  
Vittoria Cuteri ◽  
Giulia Minori ◽  
Gloria Gagliardi ◽  
Fabio Tamburini ◽  
Elisabetta Malaspina ◽  
...  

Abstract Purpose: attention has recently been paid to Clinical Linguistics for the detection and support of clinical conditions. Many works have been published on the “linguistic profile” of various clinical populations, but very few papers have been devoted to linguistic changes in patients with eating disorders. Patients with Anorexia Nervosa (AN) share similar psychological features such as disturbances in self-perceived body image, inflexible and obsessive thinking and anxious or depressive traits. We hypothesize that these characteristics can result in altered linguistic patterns and be detected using the Natural Language Processing tools. Methods: we enrolled 51 young participants from December 2019 to February 2020 (age range: 14-18): 17 girls with a clinical diagnosis of AN, and 34 normal weighted peers, matched by gender, age and educational level. Participants in each group were asked to produce three written texts (around 10-15 lines long). A rich set of linguistic features was extracted from the text samples and the statistical significance in pinpointing the pathological process was measured.Results: comparison between the two groups showed several linguistics indexes as statistically significant, with syntactic reduction as the most relevant trait of AN productions. Conclusion: these preliminary data showed the existence of linguistic parameters as probable linguistic markers of AN. However, the analysis of a bigger cohort, still ongoing, is needed to consolidate this assumption.Level of evidence III: evidence obtained from case-control analytic studies.


2013 ◽  
Vol 1 (1) ◽  
pp. 35-43
Author(s):  
Sandaruwan Prabath Kumara Ranatunga

Authorship verification rely on identification of a given document is written by a particular author or not. Internally analyzing the document itself with respect to the variations in writing style of the author and identification of the author’s own idiolect is the main context of the authorship verification. Mainly, the detection performance depends on the used feature set for clustering the document. Linguistic features and stylistic features have been utilized for author identification according to the writing style of a particular author. Disclose the shallow changes of the author’s writing style is the major problem which should be addressed in the domain of authorship verification. It motivates the computer science researchers to do research on authorship verification in the field of computer forensics and this research also focuses this problem. The contributions from the research are two folded: Former is introducing a new feature extracting method with Natural Language Processing (NLP) and later is propose a new more efficient linguistic feature set for verification of author of the given document. Experiments on a corpus composed of freely downloadable genuine 19th century English Books and Self Organizing Maps has been used as the classifier to cluster the documents. Proper word segmentation also introduced in this work and it helps to demonstrate that the proposed strategy can produced promising results. Finally, it is realized that more accurate classification is generated by the proposed strategy with extracted linguistic feature set.


2019 ◽  
Vol 35 (2) ◽  
pp. 471-484
Author(s):  
Chunlin Wang ◽  
Irene Castellón ◽  
Elisabet Comelles

Abstract Semantic Textual Similarity (STS), which measures the equivalence of meanings between two textual segments, is an important and useful task in Natural Language Processing. In this article, we have analyzed the datasets provided by the Semantic Evaluation (SemEval) 2012–2014 campaigns for this task in order to find out appropriate linguistic features for each dataset, taking into account the influence that linguistic features at different levels (e.g. syntactic constituents and lexical semantics) might have on the sentence similarity. Results indicate that a linguistic feature may have a different effect on different corpus due to the great difference in sentence structure and vocabulary between datasets. Thus, we conclude that the selection of linguistic features according to the genre of the text might be a good strategy for obtaining better results in the STS task. This analysis could be a useful reference for measuring system building and linguistic feature tuning.


Author(s):  
Shizhe Chen ◽  
Qin Jin ◽  
Alexander Hauptmann

Bilingual lexicon induction, translating words from the source language to the target language, is a long-standing natural language processing task. Recent endeavors prove that it is promising to employ images as pivot to learn the lexicon induction without reliance on parallel corpora. However, these vision-based approaches simply associate words with entire images, which are constrained to translate concrete words and require object-centered images. We humans can understand words better when they are within a sentence with context. Therefore, in this paper, we propose to utilize images and their associated captions to address the limitations of previous approaches. We propose a multi-lingual caption model trained with different mono-lingual multimodal data to map words in different languages into joint spaces. Two types of word representation are induced from the multi-lingual caption model: linguistic features and localized visual features. The linguistic feature is learned from the sentence contexts with visual semantic constraints, which is beneficial to learn translation for words that are less visual-relevant. The localized visual feature is attended to the region in the image that correlates to the word, so that it alleviates the image restriction for salient visual representation. The two types of features are complementary for word translation. Experimental results on multiple language pairs demonstrate the effectiveness of our proposed method, which substantially outperforms previous vision-based approaches without using any parallel sentences or supervision of seed word pairs.


Author(s):  
Pawan Kumar Saini ◽  
Devendra Yadav ◽  
Rozy Badyal ◽  
Suresh Jain ◽  
Arti Singh ◽  
...  

Background: Psoriasis is an autoimmune chronic inflammatory disorder affecting the skin mediated by T-lymphocytes resulting in production of cytokines which cause hyperproliferation of keratinocytes.  Several factors and hormones like Prolactin have an action similar to these cytokines in promoting the multiplication of keratinocytes and other cells like lymphocytes and epithelial cells may have a role on the etiopathogenesis of psoriasis. Aim:-The aim of study is to compare the serum Prolactin levels in patients of psoriasis with a control group. Setting and study design: This is a case-control study conducted in the department of Dermatology, Venereology and Leprosy GMC, Kota over a period of 1year from July 2017 to June 2018 Material and method: The study included 100 cases of psoriasis (60 males and 40 females) and 100 controls similar for age and sex. Serum Prolactin levels were measured by ECLIA and results were obtained. Statistical analysis: Mean and standard deviation were calculated for each variable. Statistical significance of the results was analyzed using correlation analysis (Pearson correlation coefficient) and independent samples t-test. Statistical significance was assumed at p value<0.05. Result: Serum Prolactin level was significantly higher in cases of psoriasis compared to controls (p-value <0.001). PASI score and serum Prolactin levels were found to have a positive correlation (r value = 0.337; p-value: 0.001). No significant  correlation was found between serum levels of Prolactin and duration of disease r value= -0.034, P value =0.733). Serum Prolactin level was higher in male patients compared to females patients. Conclusion:- High serum Prolactin may be a biological marker of disease severity in psoriasis and may have a role in the pathogenesis of psoriasis. Further studies with large sample size are required to confirm this hypothesis.


Author(s):  
Una Stojnić

On the received view, the resolution of context-sensitivity is at least partly determined by non-linguistic features of utterance situation. If I say ‘He’s happy’, what ‘he’ picks out is underspecified by its linguistic meaning, and is only fixed through extra-linguistic supplementation: the speaker’s intention, and/or some objective, non-linguistic feature of the utterance situation. This underspecification is exhibited by most context-sensitive expressions, with the exception of pure indexicals, like ‘I.’ While this received view is prima facie appealing, I argue it is deeply mistaken. I defend an account according to which context-sensitivity resolution is governed by linguistic mechanisms determining prominence of candidate resolutions of context-sensitive items. Thus, on this account, the linguistic meaning of a context-sensitive expression fully specifies its resolution in a context, automatically selecting the resolution antecedently set by the prominence-governing linguistic mechanisms.


2021 ◽  
pp. 1-8
Author(s):  
Regina Sá ◽  
Tiago Pinho-Bandeira ◽  
Guilherme Queiroz ◽  
Joana Matos ◽  
João Duarte Ferreira ◽  
...  

<b><i>Background:</i></b> Ovar was the first Portuguese municipality to declare active community transmission of SARS-CoV-2, with total lockdown decreed on March 17, 2020. This context provided conditions for a large-scale testing strategy, allowing a referral system considering other symptoms besides the ones that were part of the case definition (fever, cough, and dyspnea). This study aims to identify other symptoms associated with COVID-19 since it may clarify the pre-test probability of the occurrence of the disease. <b><i>Methods:</i></b> This case-control study uses primary care registers between March 29 and May 10, 2020 in Ovar municipality. Pre-test clinical and exposure-risk characteristics, reported by physicians, were collected through a form, and linked with their laboratory result. <b><i>Results:</i></b> The study population included a total of 919 patients, of whom 226 (24.6%) were COVID-19 cases and 693 were negative for SARS-CoV-2. Only 27.1% of the patients reporting contact with a confirmed or suspected case tested positive. In the multivariate analysis, statistical significance was obtained for headaches (OR 0.558), odynophagia (OR 0.273), anosmia (OR 2.360), and other symptoms (OR 2.157). The interaction of anosmia and odynophagia appeared as possibly relevant with a borderline statistically significant OR of 3.375. <b><i>Conclusion:</i></b> COVID-19 has a wide range of symptoms. Of the myriad described, the present study highlights anosmia itself and calls for additional studies on the interaction between anosmia and odynophagia. Headaches and odynophagia by themselves are not associated with an increased risk for the disease. These findings may help clinicians in deciding when to test, especially when other diseases with similar symptoms are more prevalent, namely in winter.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Homeira Vafaei ◽  
Zinat Karimi ◽  
Mojgan Akbarzadeh-Jahromi ◽  
Fatemeh Asadian

Abstract Background Chorangiosis is a vascular change involving the terminal chorionic villi in the placenta. It results from longstanding, low-grade hypoxia in the placental tissue, and is associated with such conditions as intrauterine growth restriction (IUGR), diabetes, and gestational hypertension in pregnancy. Chorangiosis rarely occurs in normal pregnancies. However, its prevalence is 5–7% of all placentas from infants admitted to newborn intensive care units. The present study was aimed at determining the association of chorangiosis with pregnancy complications and perinatal outcomes. Methods In this case-control study, 308 chorangiosis cases were compared with 308 controls (with other diagnoses in pathology) in terms of maternal, placental, prenatal, and neonatal characteristics derived from the medical records of participants retrospectively. R and SPSS version 22 software tools were used, and the statistical significance level was considered 0.05 for all the tests. Results Preeclampsia, diabetes mellitus, maternal hemoglobin, maternal hematocrit, C/S, oligohydramnios, fetal anomaly, dead neonates, NICU admissions were significantly higher in the chorangiosis group OR = 1.6, 3.98, 1.68, 1.92, 2.1, 4.47, 4.22, 2.9, 2.46, respectively (p-value< 0.05 for all). Amniotic fluid index, birth weight, cord PH amount, 1st, and 5th Apgar score was lower in the chorangiosis group OR = 0.31, 1, 0.097, 0.83, 0.85, respectively (p-value< 0.05 for all). Moreover, fundal placenta, retro placental hemorrhage, perivillous fibrin deposition, calcification, and acute chorioamnionitis were higher in the chorangiosis group OR = 2.1, 11.8, 19.96, 4.05, and 6.38 respectively, (p-value< 0.05). There was a high agreement between the two pathologists, and the power of the study was estimated at 99%. Conclusion Although chorangiosis is an uncommon condition, it is associated with a higher incidence of perinatal and neonatal morbidity and mortality. Therefore, it should be considered an important clinical sign of adverse pregnancy outcomes and should be reported in the pathology evaluation.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Daniel Muder ◽  
Nils P. Hailer ◽  
Torbjörn Vedung

Abstract Background The aim of our study was to compare the long-term outcome after perichondrium transplantation and two-component surface replacement (SR) implants to the metacarpophalangeal (MCP) and the proximal interphalangeal (PIP) joints. Methods We evaluated 163 joints in 124 patients, divided into 138 SR implants in 102 patients and 25 perichondrium transplantations in 22 patients. Our primary outcome was any revision surgery of the index joint. Results The median follow-up time was 6 years (0–21) for the SR implants and 26 years (1–37) for the perichondrium transplants. Median age at index surgery was 64 years (24–82) for SR implants and 45 years (18–61) for perichondium transplants. MCP joint survival was slightly better in the perichondrium group (86.7%; 95% confidence interval [CI]: 69.4–100.0) than in the SR implant group (75%; CI 53.8–96.1), but not statistically significantly so (p = 0.4). PIP joint survival was also slightly better in the perichondrium group (80%; CI 55–100) than in the SR implant group (74.7%; CI 66.6–82.7), but below the threshold of statistical significance (p = 0.8). Conclusion In conclusion, resurfacing of finger joints using transplanted perichondrium is a technique worth considering since the method has low revision rates in the medium term and compares favorable to SR implants. Level of evidence III (Therapeutic).


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