scholarly journals LIONESS Lab: a free web-based platform for conducting interactive experiments online

2020 ◽  
Vol 6 (1) ◽  
pp. 95-111 ◽  
Author(s):  
Marcus Giamattei ◽  
Kyanoush Seyed Yahosseini ◽  
Simon Gächter ◽  
Lucas Molleman

Abstract LIONESS Lab is a free web-based platform for interactive online experiments. An intuitive, user-friendly graphical interface enables researchers to develop, test, and share experiments online, with minimal need for programming experience. LIONESS Lab provides solutions for the methodological challenges of interactive online experimentation, including ways to reduce waiting time, form groups on-the-fly, and deal with participant dropout. We highlight key features of the software, and show how it meets the challenges of conducting interactive experiments online.

2021 ◽  
Author(s):  
Dinodi Divyanjana Rajapaksha ◽  
Mohamed Nafeel Mohamed Nuhuman ◽  
Sewmini Dananji Gunawardhana ◽  
Atchuthan Sivalingam ◽  
Mohamed Nimran Mohamed Hassan ◽  
...  

2016 ◽  
Vol 17 (3) ◽  
pp. 188-194 ◽  
Author(s):  
Gabriel Andrés Torres-Londoño ◽  
Mary Hausbeck ◽  
Jianjun Hao

Spiral plating technique is reliable, repeatable, and more efficient than dilution plating methods in studying the efficacy of antimicrobial products. In this method, the concentration of chemicals can be varied at different positions on agar plates, but its calculation requires using a commercial software. To establish a user-friendly and cost-free platform, the R package ECX was developed to calculate chemical concentrations in spiral plating technique. Mathematical models were established for calculating dispensed volume on agar plates using variables (molecular weight and agar height) that affect diffusion. In addition to the R packages, the web-based Shiny extensions ECX, multi, and ppm were developed to provide a graphical interface for calculating individual concentrations, multiple concentrations, and stock concentrations, respectively. No significant differences were observed (P > 0.05) when ECX was compared with the commercial software. The ability to import and process large datasets makes the ECX package a better option for spiral plating technique studies. Furthermore, the multiplatform nature of the ECX package overcomes limitations presented in other software. Therefore, these ECX characteristics can increase the use of the spiral plating technique for sensitivity studies. Accepted for publication 21 June 2016.


2021 ◽  
Author(s):  
Sebastiaan Mathot ◽  
Jennifer March

In this Methods Showcase, we outline a workflow for running behavioral experiments online, with a focus on linguistic experiments. The workflow that we describe here relies on three tools: OpenSesame/ OSWeb (open source) provides a user-friendly graphical interface for developing experiments; JATOS (open source) is server software for hosting experiments; and Prolific (commercial) is a platform for recruiting participants. These three tools integrate well with each other, and together they provide a workflow that requires little technical expertise. We discuss several challenges that are associated with running online experiments, including temporal precision, the ability to implement counterbalancing, and data quality. We conclude that these problems are real but surmountable, and that in many cases online experiments are a viable alternative to laboratory-based experiments.


2021 ◽  
Author(s):  
Shuyu Zheng ◽  
Jehad Aldahdooh ◽  
Tolou Shadbahr ◽  
Yinyin Wang ◽  
Dalal Aldahdooh ◽  
...  

Combinatorial therapies that target multiple pathways have shown great promises for treating complex diseases. DrugComb (https://drugcomb.org/) is a web-based portal for the deposition and analysis of drug combination screening datasets. Since its first release, DrugComb has received continuous updates on the coverage of data resources, as well as on the functionality of the web server to improve the analysis, visualization and interpretation of drug combination screens. Here we report significant updates of DrugComb, including: 1) manual curation and harmonization of more comprehensive drug combination and monotherapy screening data, not only for cancers but also for other diseases such as malaria and COVID-19; 2) enhanced algorithms for assessing the sensitivity and synergy of drug combinations; 3) network modelling tools to visualize the mechanisms of action of drugs or drug combinations for a given cancer sample; and 4) state-of-the-art machine learning models to predict drug combination sensitivity and synergy. These improvements have been provided with more user-friendly graphical interface and faster database infrastructure, which make DrugComb the most comprehensive web-based resources for the study of drug sensitivities for multiple diseases.


2017 ◽  
Vol 1 (1) ◽  
pp. 44-49
Author(s):  
Nur Azizah ◽  
Dedeh Supriyanti ◽  
Siti Fairuz Aminah Mustapha ◽  
Holly Yang

In a company, the process of income and expense of money must have a profit-generating goal base. The success of financial management within the company, can be monitored from the ability of the financial management in managing the finances and utilize all the opportunities that exist with as much as possible with the aim to control the company's cash (cash flow) and the impact of generating profits in accordance with expectations. With a web-based online accounting system version 2.0, companies can be given the ease to manage money in and out of the company's cash. It has a user friendly system with navigation that makes it easy for the financial management to use it. Starting from the creation of a company's cash account used as a cash account and corporate bank account on the system, deletion or filing of cash accounts, up to the transfer invoice creation feature, receive and send money. Thus, this system is very effective and efficient in the management of income and corporate cash disbursements.   Keywords:​Accounting Online System, Financial Management, Cash and Bank


2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Mehmet EMIN KORTAK

This research aimed at designing and improving the web-based integrated peer and self- assessment. WesPASS (web-based peer-assessment system), developed in this research, allows students to assess their own or their peers’ performance and project assignments and to report about the result of these assessments so that they correct their assignments. This study employed design-based research. The participants included 102 fourth grade primary school students and their 4 teachers from 2 state and 2 private primary schools in Ankara, Kecioren (Turkey) who employed the system and were engaged in a questionnaire survey to assess its quality. The findings were analyzed through quantitative data analysis. The findings revealed that the system can be used by elementary school students for peer and self-assessment system. The participants stated that WesPASS is simple and user-friendly, and it accelerates the assessment process by employing information technology and allows to share opinions 


Author(s):  
Sagar Pathane ◽  
Uttam Patil ◽  
Nandini Sidnal

The agricultural commodity prices have a volatile nature which may increase or decrease inconsistently causing an adverse effect on the economy. The work carried out here for predicting prices of agricultural commodities is useful for the farmers because of which they can sow appropriate crop depending on its future price. Agriculture products have seasonal rates, these rates are spread over the entire year. If these rates are known/alerted to the farmers in advance, then it will be promising on ROI (Return on Investments). It requires that the rates of the agricultural products updated into the dataset of each state and each crop, in this application five crops are considered. The predictions are done based on neural networks Neuroph framework in java platform and also the previous years data. The results are produced on mobile application using android. Web based interface is also provided for displaying processed commodity rates in graphical interface. Agricultural experts can follow these graphs and predict market rates which can be informed to the farmers. The results will be provided based on the location of the users of this application.


Metabolites ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 113
Author(s):  
Julia Koblitz ◽  
Sabine Will ◽  
S. Riemer ◽  
Thomas Ulas ◽  
Meina Neumann-Schaal ◽  
...  

Genome-scale metabolic models are of high interest in a number of different research fields. Flux balance analysis (FBA) and other mathematical methods allow the prediction of the steady-state behavior of metabolic networks under different environmental conditions. However, many existing applications for flux optimizations do not provide a metabolite-centric view on fluxes. Metano is a standalone, open-source toolbox for the analysis and refinement of metabolic models. While flux distributions in metabolic networks are predominantly analyzed from a reaction-centric point of view, the Metano methods of split-ratio analysis and metabolite flux minimization also allow a metabolite-centric view on flux distributions. In addition, we present MMTB (Metano Modeling Toolbox), a web-based toolbox for metabolic modeling including a user-friendly interface to Metano methods. MMTB assists during bottom-up construction of metabolic models by integrating reaction and enzymatic annotation data from different databases. Furthermore, MMTB is especially designed for non-experienced users by providing an intuitive interface to the most commonly used modeling methods and offering novel visualizations. Additionally, MMTB allows users to upload their models, which can in turn be explored and analyzed by the community. We introduce MMTB by two use cases, involving a published model of Corynebacterium glutamicum and a newly created model of Phaeobacter inhibens.


2021 ◽  
pp. 193229682098557
Author(s):  
Alysha M. De Livera ◽  
Jonathan E. Shaw ◽  
Neale Cohen ◽  
Anne Reutens ◽  
Agus Salim

Motivation: Continuous glucose monitoring (CGM) systems are an essential part of novel technology in diabetes management and care. CGM studies have become increasingly popular among researchers, healthcare professionals, and people with diabetes due to the large amount of useful information that can be collected using CGM systems. The analysis of the data from these studies for research purposes, however, remains a challenge due to the characteristics and large volume of the data. Results: Currently, there are no publicly available interactive software applications that can perform statistical analyses and visualization of data from CGM studies. With the rapidly increasing popularity of CGM studies, such an application is becoming necessary for anyone who works with these large CGM datasets, in particular for those with little background in programming or statistics. CGMStatsAnalyser is a publicly available, user-friendly, web-based application, which can be used to interactively visualize, summarize, and statistically analyze voluminous and complex CGM datasets together with the subject characteristics with ease.


2020 ◽  
Vol 36 (12) ◽  
pp. 3913-3915
Author(s):  
Hemi Luan ◽  
Xingen Jiang ◽  
Fenfen Ji ◽  
Zhangzhang Lan ◽  
Zongwei Cai ◽  
...  

Abstract Motivation Liquid chromatography–mass spectrometry-based non-targeted metabolomics is routinely performed to qualitatively and quantitatively analyze a tremendous amount of metabolite signals in complex biological samples. However, false-positive peaks in the datasets are commonly detected as metabolite signals by using many popular software, resulting in non-reliable measurement. Results To reduce false-positive calling, we developed an interactive web tool, termed CPVA, for visualization and accurate annotation of the detected peaks in non-targeted metabolomics data. We used a chromatogram-centric strategy to unfold the characteristics of chromatographic peaks through visualization of peak morphology metrics, with additional functions to annotate adducts, isotopes and contaminants. CPVA is a free, user-friendly tool to help users to identify peak background noises and contaminants, resulting in decrease of false-positive or redundant peak calling, thereby improving the data quality of non-targeted metabolomics studies. Availability and implementation The CPVA is freely available at http://cpva.eastus.cloudapp.azure.com. Source code and installation instructions are available on GitHub: https://github.com/13479776/cpva. Supplementary information Supplementary data are available at Bioinformatics online.


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