The relationship between Prostaglandin E1 applied area and flap survival rate

1992 ◽  
Vol 45 (6) ◽  
pp. 465-468 ◽  
Author(s):  
Yukimasa Sawada ◽  
Takatoshi Yotsuyanagi ◽  
Ichiro Hatayama ◽  
Ken Sone
2020 ◽  
Vol 29 (3) ◽  
pp. 797-826
Author(s):  
Guoqian Xi ◽  
Jörn Block ◽  
Frank Lasch ◽  
Frank Robert ◽  
Roy Thurik

Abstract Business takeovers and new venture start-ups are two important and distinct entry modes of entrepreneurship. They differ from resource-based and organizational ecology perspectives. We compare firm survival patterns and determinants associated with the two entry modes. From two large French datasets, we find that business takeovers have a higher survival rate than new venture start-ups. However, these differences in survival probability reduce over the entrepreneurship life cycle and when controlling for different entrepreneur and firm characteristics. Moreover, we identify differences in determinants of survival for the two groups, highlighting a distinction between the two entrepreneurship entry modes. This work contributes to the literature on the relationship between entrepreneurship entry and firm survival, thereby contributing to both entrepreneurship and firm survival research.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Youyou Wang ◽  
Huijun Ren ◽  
Zhaohu Pan ◽  
Ben Liu ◽  
Fan Lin

Objective. To investigate the expression of miR-338-3p in nasopharyngeal carcinoma (NPC) and its relationship with STAT3 mRNA expression as well as their relationship with clinical pathological parameters and prognosis of patients. Methods. From September 2016 to September 2018, 71 patients with NPC were selected as the NPC group, and 71 samples of NPC tissues were collected during the operation. A total of 23 patients who underwent biopsy due to chronic nasopharyngitis were selected as the control group and 23 nasopharyngeal mucosal tissues were collected. The expressions of miR-338-3p and STAT3 mRNA in nasopharyngeal tissue of two groups were detected by real-time quantitative PCR, and the relationship between the two was analyzed. To collect clinical data of NPC patients and analyze the relationship between the expressions of miR-338-3p and STAT3 in NPC tissues and clinical pathological parameters of the patients, we followed up the patients with nasopharyngeal carcinoma for three years to observe the relationship between miR-338-3p, STAT3, and the prognosis of the patients. Results. The relative expression levels of miR-338-3p in nasopharyngeal tissues of the NPC group and the control group were 0.39 ± 0.05 and 1.01 ± 0.09, respectively ( P  < 0.05). The relative expression levels of STAT3 mRNA in nasopharyngeal tissues of the NPC group and the control group were 3.82 ± 0.21 and 1.04 ± 0.11, respectively ( P  > 0.05). miR-338-3p was negatively correlated with the relative expression of STAT3 mRNA in nasopharyngeal carcinoma (r = 0.038, P  > 0.05). The expression of miR-338-3p was related to the age of the patient, clinical TNM stage, T stage, and distant metastasis (all P  < 0.05). STAT3 expression was correlated with clinical TNM stage, T stage, and distant metastasis in our patient ( P  < 0.05). The expressions of miR-338-3p and STAT3 in nasopharyngeal carcinoma tissues from different gender, histological type, N stage, M stage, and degree of differentiation showed no statistical differences ( P  > 0.05). The survival rate of the group with low miR-338-3p expression was significantly lower than that of the group with high miR-338-3p expression ( P  > 0.05). The survival rate of patients with the high STAT3 expression group was significantly lower than that of patients with the low STAT3 expression group ( P  > 0.05). Conclusion. There is a negative correlation between the low expression of miR-338-3p and the high expression of STAT3 in NPC, which are all related to the TNM stage, T stage, and prognosis of the patient.


Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Chisato Izumi ◽  
Shuichi Takahashi ◽  
Sumiyo Hashiwada ◽  
Koji Hanazawa ◽  
Jiro Sakamoto ◽  
...  

Atheromatous plaques of the aorta have been regarded as a potential source of emboli, but there are few reports about the frequency and prognosis of patients with thoracic aortic plaques and about the relationship between plaque morphology and prognosis, especially long-term follow-up data. The purpose of this study is to clarify the impact of aortic atheromatous plaque morphology on survival rate and the incidence of subsequent embolic event. We retrospectively investigated 1570 consecutive patients who underwent transesophageal echocardiography between 1991 and 2003. The presence of severe plaque (>5mm in thickness) in the thoracic aorta were examined. Survival rate and subsequent embolic event rate were compared between patients with severe plaque and 109 control patients. The control patients were selected from the patients who showed no or mild plaque and as they were matched for age, gender, and risk factors of atherosclerosis with the patients with severe aortic plaque. The relationship between aortic plaque morphology and prognosis was also estimated, according to the presence of ulceration, calcification, hypoechoic plaques, and mobile plaques. Mean follow-up period was 8.7 years. Among 1570 patients, severe aortic plaque was detected in 92 patients (5.9%). These 92 patients showed significantly low survival rate and high subsequent embolic event rate compared with control patients (8-year survival rate, 50% vs 87%, 8-year embolic event free rate, 57% vs 90%). The relative risk of death was significantly increased for ulceration (2.4, 95% CI;1.1–5.2) and the relative risk of embolic events was significantly increased for mobile plaques (2.2, 95% CI;1.1–5.1). In conclusion, aortic plaque > 5mm in thickness was a predictor of a low survival rate and a high embolic event rate. Among patients with aortic plaque >5mm in thickness, ulceration was a predictor of a low survival rate and mobile plaque was a predictor of a high embolic event rate.


1990 ◽  
Vol 9 (6) ◽  
pp. 381-384 ◽  
Author(s):  
Hiroshi Yamaguchi ◽  
Shigehito Sato ◽  
Seiji Watanabe ◽  
Hiroshi Naito

1 In order to assess which laboratory parameters could be related to the prognosis of patients with acute paraquat poisoning, we reviewed the medical records of 160 patients who had ingested paraquat in an attempt at suicide. 2 Serum creatinine and potassium concentrations, arterial blood bicarbonate and base excess levels, arterial blood pH, volume of paraquat ingested and the strength of the urinary paraquat qualitative test (sodium dithionate colour reaction) on admission in the surviving patients were significantly different from those of the patients who died within 48 h of ingestion. 3 The relationship of the quantity Eq1 defined as: Eq1 = ([K +] × [HCO-3]) / ([Cre] × 0.088) (mEq l-1 ) against the interval of time after ingestion to admission (T) had a significant correlation with prognosis ( P < 0.01). Patients with Eq1 > (1500 - 399 × LogT) had a 90% survival rate, Eq1: (930 - 399 × LogT) < Eq1 ≤ (1500 - 399 × LogT) 38% and Eq1 ≤ (930 - 399 × LogT) 3%, P < 0.01.


Parasitology ◽  
1989 ◽  
Vol 99 (1) ◽  
pp. 47-56 ◽  
Author(s):  
M. E. J. Woolhouse

SUMMARYThe prevalence of schistosome infections in intermediate host snails varies with snail age. The relationship between age and prevalence, the age—prevalence curve, is complex and may vary in space and time, and among parasite—host species. Field studies show that the shape of the age—prevalence curve may be seasonally variable, and that at some times there may be a decline in prevalence among older snails. This paper attempts to explain these observations in terms of the underlying epidemiological processes. A discrete-time version of Muench's catalytic model for age-dependent infection is developed. Model simulations were carried out using life-history and epidemiological parameters derived from studies ofSchistosoma haematobium—Bulinus globususin Zimbabwe. Analysis of model behaviour identifies aspects of the schistosome— snail interaction that affect the shape of the age—prevalence curve. The following features can result in a decline in prevalence among older snails. (1) A decrease in the survival rate of patent infected snails with age. (2) A decrease in the force of infection with age. (3) A high rate of loss of infection. (4) A heterogeneity in the snail population such that the probability of infection is correlated with snail fecundity. (This would occur if there existed a spatial correlation between force of infection and fecundity, or if there were a correlation between fecundity and susceptibility.) The evidence for the occurrence of these features in the field is assessed. Survival rate is related more closely to the duration of patent infection than to ageper se. The evidence for age-dependent force of infection is equivocal. Significant loss-of-infection rates have yet to be demonstrated. Heterogeneities in force of infection and fecundity have been reported and, for the Zimbabwe data, this mechanism can explain seasonally in the age—prevalence curve as a function of known seasonal variation in the force of infection and snail fecundity.


1998 ◽  
Vol 75 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Shigeru Ichioka ◽  
Takashi Nakatsuka ◽  
Yuko Sato ◽  
Masahiro Shibata ◽  
Akira Kamiya ◽  
...  

2017 ◽  
Vol 33 (09) ◽  
pp. 660-669 ◽  
Author(s):  
Hyunsuk Suh ◽  
Eun Park ◽  
Joon Hong

Background An ideal vessel dissection will be to maximize bleeding control through coagulation while minimizing vessel damage. Among the diathermy methods, there has been no report comparing the effect on vessels. This study aims to verify the effect of bipolar diathermy against monopolar diathermy cutting mode for vessel dissection. Methods A total of 18 Sprague–Dawley rats were divided into three groups according to the method of pedicle dissection for 6 × 6 cm sized abdominal flap; (group 0) surgical scissors, (group 1) monopolar diathermy cutting mode and (group 2) bipolar diathermy. They were evaluated for the temperature of device tip and the radiating heat to the surrounding tissue, change in vessel diameter, flow velocity, and perfusion to the skin flap during dissection. Final flap survival rate and pathology of the vessels were also evaluated. Results Significantly higher radiating heat was observed using bipolar diathermy (average: 37.5°C) compared with group using monopolar diathermy (average: 34.4°C) (p value 0.045). However, there were no differences in vessel diameter, skin flap perfusion, flow velocity, and flap survival rate among the groups. Conclusions Both monopolar diathermy cutting mode and bipolar diathermy are safe to use to dissect the pedicle vessels when used adequately. Although it has no significant difference in relations to flap survival, vessel spasm, and perfusion/velocity to the flap, the extent of histologic damage may be less in monopolar diathermy cutting mode. Using monopolar diathermy cutting mode may provide efficiency to achieve ligation in small vessels during pedicle dissection but requires finesse technique and a learning curve.


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