The rapid differentiation and identification of pathogenic bacteria using Fourier transform infrared spectroscopic and multivariate statistical analysis

1988 ◽  
Vol 174 ◽  
pp. 165-170 ◽  
Author(s):  
D. Naumann ◽  
V. Fijala ◽  
H. Labischinski ◽  
P. Giesbrecht
2014 ◽  
Vol 926-930 ◽  
pp. 1116-1119 ◽  
Author(s):  
Li Jun Yang ◽  
Jing Wang ◽  
Zhao Jie Li ◽  
Xiao Hua Song ◽  
Yu Min Liu ◽  
...  

Fourier transform infrared spectroscopy (FTIR) combined with multivariate statistical analysis was applied to differentiate and identify Shigella sonnei and Escherichiacoli O157: H7. FTIR absorption spectra from 4000-600 cm-1 were collected from sampling 10 μL of bacterial suspention. The spectra between 1800 and 900 cm-1 highlighted the most distinctive variations and were the most useful for characterizing the selected microorganisms. Spectra of the two bacteria were noticeably segregated with distinct clustering by principal component analysis (PCA). Further more, another cluster model of hierarchical cluster analysis (HCA) was established and could also gave a good separation between the two bacteria. These results demonstrate that FTIR technology has considerable potential as a rapid, accurate and simple method for differentiating and identifying bacteria.


2018 ◽  
Vol 52 (2) ◽  
pp. 15
Author(s):  
V. I. Radomskaya ◽  
D. V. Yusupov ◽  
L. М. Pavlova ◽  
А. G. Sеrgееvа ◽  
N. А. Bоrоdinа ◽  
...  

2017 ◽  
Vol 68 (4) ◽  
pp. 726-731
Author(s):  
Lenuta Maria Suta ◽  
Anca Tudor ◽  
Colette Roxana Sandulovici ◽  
Lavinia Stelea ◽  
Daniel Hadaruga ◽  
...  

In this paper, it was analysed the influence of formulation factors over obtaining oxicam hydrogels, using the statistical analysis. Data analysis and predictive modeling by multivariate regression offers a large number of possible explanatory/predictive variables. Therefore, variable selection and dimension reduction is a major task for multivariate statistical analysis, especially for multivariate regressions. The statistical analysis and computational data processing of responses obtained from different pharmaceutical formulations, via different experimental protocols, lead to the optimization of the formulation process. It was found that the most suitable pharmaceutical formulations based on oxicams with the possibility of rapid release contained cyclodextrin, in particular 2-hydroxypropyl-b-cyclodextrin.


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