Molecular cloning of rat cDNAs for the ζ and θ subtypes of 14-3-3 protein and differential distributions of their mRNAs in the brain

1994 ◽  
Vol 25 (1-2) ◽  
pp. 113-121 ◽  
Author(s):  
Masahiko Watanabe ◽  
Toshiaki Isobe ◽  
Tohru Ichimura ◽  
Ryozo Kuwano ◽  
Yasuo Takahashi ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
The Brain

scholarly journals Molecular cloning of the gene encoding the bovine brain ribonucelase and its expression in different regions of the brain

1991 ◽  
Vol 19 (23) ◽  
pp. 6469-6474 ◽  
Author(s):  
M.P. Sasso ◽  
A. Carsana ◽  
E. Confalone ◽  
C. Cosi ◽  
S. Sorrentino ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
Bovine Brain ◽  
Gene Encoding ◽  
The Brain

scholarly journals Molecular Cloning of cDNA for BRab from the Brain ofBombyx moriand Biochemical Properties of BRab Expressed inEscherichia coli

1998 ◽  
Vol 62 (10) ◽  
pp. 1885-1891 ◽  
Author(s):  
Tomohide UNO ◽  
Mayumi UENO ◽  
Ayumi NAKAJIMA ◽  
Yasuhito SHIRAI ◽  
Yasuo AIZONO
Keyword(s):  
Molecular Cloning ◽  
Biochemical Properties ◽  
Inescherichia Coli ◽  
The Brain

scholarly journals A half century of γ-aminobutyric acid

2019 ◽  
Vol 3 ◽  
pp. 239821281985824 ◽  
Author(s):  
Trevor G Smart ◽  
F Anne Stephenson
Keyword(s):  
Nervous System ◽  
Molecular Cloning ◽  
Brain Function ◽  
Drug Targets ◽  
Neurological Diseases ◽  
Aminobutyric Acid ◽  
Receptor Subtypes ◽  
Acid Receptor ◽  
Neural Excitability ◽  
The Brain

γ-aminobutyric acid has become one of the most widely known neurotransmitter molecules in the brain over the last 50 years, recognised for its pivotal role in inhibiting neural excitability. It emerged from studies of crustacean muscle and neurons before its significance to the mammalian nervous system was appreciated. Now, after five decades of investigation, we know that most neurons are γ-aminobutyric-acid-sensitive, it is a cornerstone of neural physiology and dysfunction to γ-aminobutyric acid signalling is increasingly documented in a range of neurological diseases. In this review, we briefly chart the neurodevelopment of γ-aminobutyric acid and its two major receptor subtypes: the γ-aminobutyric acidA and γ-aminobutyric acidB receptors, starting from the humble invertebrate origins of being an ‘interesting molecule’ acting at a single γ-aminobutyric acid receptor type, to one of the brain’s most important neurochemical components and vital drug targets for major therapeutic classes of drugs. We document the period of molecular cloning and the explosive influence this had on the field of neuroscience and pharmacology up to the present day and the production of atomic γ-aminobutyric acidA and γ-aminobutyric acidB receptor structures. γ-Aminobutyric acid is no longer a humble molecule but the instigator of rich and powerful signalling processes that are absolutely vital for healthy brain function.

scholarly journals Molecular Cloning of Canine Monoamine Oxidase Subtypes A (MAOA) and B (MAOB) cDNAs and Their Expression in the Brain

2003 ◽  
Vol 65 (8) ◽  
pp. 893-898 ◽  
Author(s):  
Chie HASHIZUME ◽  
Masatoshi SUZUKI ◽  
Koji MASUDA ◽  
Yukihide MOMOZAWA ◽  
Takefumi KIKUSUI ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Molecular Cloning ◽  
The Brain

Molecular cloning of novel murine zinc finger protein genes which are expressed in stage and region specific pattern in the brain

1994 ◽  
Vol 19 ◽  
pp. S132
Author(s):  
Kazuhiko Namikawa ◽  
Naonori Morita ◽  
Jun Suzuki ◽  
Keiko Kato ◽  
Sadao Shiosaka ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Specific Pattern ◽  
Finger Protein ◽  
The Brain
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