APPLICATION OF A VOLATILE RADIOACTIVE TRACER TO DETECT METABOLIC ACTIVITIES IN DRY WILD OAT SEEDS11Supported by NSF Grant GB-30750

Space Lab 3 (SL-3) was flown on Shuttle Challenger providing an opportunity to measure the effect of spaceflight on rat testes. Cannon developed the idea that organisms react to unfavorable conditions with highly integrated metabolic activities. Selye summarized the manifestations of physiological response to nonspecific stress and he pointed out that atrophy of the gonads always occurred. Many papers have been published showing the effects of social interaction, crowding, peck order and confinement. Flickinger showed delayed testicular development in subordinate roosters influenced by group numbers, social rank and social status. Christian reported increasing population size in mice resulted in adrenal hypertrophy, inhibition of reproductive maturation and loss of reproductive function in adults. Sex organ weights also declined. Two male dogs were flown on Cosmos 110 for 22 days. Fedorova reported an increase of 30 to 70% atypical spermatozoa consisting of tail curling and/or the absence of a tail.

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Artificial cells containing sustainable energy conversion engines

Emerging Topics in Life Sciences ◽

10.1042/etls20190103 ◽

2019 ◽

Vol 3 (5) ◽

pp. 573-578 ◽

Cited By ~ 3

Author(s):

Kwanwoo Shin

Keyword(s):

Energy Conversion ◽

Nicotinamide Adenine Dinucleotide ◽

Sustainable Energy ◽

Living Cells ◽

Energy Transduction ◽

Artificial Cells ◽

Energy Conversion Process ◽

Metabolic Reactions ◽

Metabolic Activities ◽

Reduced Nicotinamide Adenine Dinucleotide

Living cells naturally maintain a variety of metabolic reactions via energy conversion mechanisms that are coupled to proton transfer across cell membranes, thereby producing energy-rich compounds. Until now, researchers have been unable to maintain continuous biochemical reactions in artificially engineered cells, mainly due to the lack of mechanisms that generate energy-rich resources, such as adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide (NADH). If these metabolic activities in artificial cells are to be sustained, reliable energy transduction strategies must be realized. In this perspective, this article discusses the development of an artificially engineered cell containing a sustainable energy conversion process.

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Description of a Simple Model for the Study of Bone Calcium Metabolism

Nuklearmedizin ◽

10.1055/s-0037-1620923 ◽

1980 ◽

Vol 19 (01) ◽

pp. 11-15

Author(s):

G. Roncari ◽

L. Rapisardi ◽

L. Conte ◽

G. Pedroli

Keyword(s):

Simple Model ◽

Calcium Metabolism ◽

Good Description ◽

Radioactive Tracer ◽

Normal Subjects ◽

Bone Diseases ◽

Compartment System ◽

Bone Calcium ◽

Finite Period ◽

Kinetics Of

A simple model for the study of bone calcium metabolism is proposed. It describes the kinetics of a radioactive tracer in terms of an open single compartment system with an expanding volume for a finite period of time. In addition to the simplicity of the hypotheses introduced, the model is able to give a good description of the biological processes which regulate calcium kinetics. Moreover the functional parameters can be easily calculated, even just graphically. 15 normal subjects and 22 patients affected by various bone diseases were studied. The results were compared with those obtained by using the model proposed by Burkinshaw et al. and the method described by Reeve et al.

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SiO2 Entrapment of Animal Cells for Hybrid Bioartificial Organs

MRS Proceedings ◽

10.1557/proc-628-cc10.1 ◽

2000 ◽

Vol 628 ◽

Cited By ~ 6

Author(s):

Giovanni Carturan ◽

Renzo Dal Monte ◽

Maurizio Muraca

Keyword(s):

Gas Phase ◽

Mechanical Stability ◽

Porous Silica ◽

Collagen Matrix ◽

Homogeneous Layer ◽

Animal Cells ◽

Bioartificial Organs ◽

Liver And Pancreas ◽

Encapsulation Method ◽

Metabolic Activities

ABSTRACTSi-alkoxides in gas phase are reactive towards the surface of animal cells, depositing a homogeneous layer of porous silica. This encapsulation method preserves cell viability and does not alter the hindrance of the biological load.In the prospective use for the design of a hybrid bioartificial liver, hepatocytes in a collagen matrix can be entrapped by the siliceous deposit which provides definite mechanical stability to the collagen matrix and molecular cutoff vs. high molecular weight proteins, including immunoglobulins. The functionality of the encapsulated cell load is maintained for the expressions of typical liver and pancreas metabolic activities.

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Herbicidal potential of Aerva javanica to control wild oat in wheat crop

Allelopathy Journal ◽

10.26651/allelo.j/2020-51-2-1299 ◽

2020 ◽

Vol 51 (2) ◽

pp. 177-194

Author(s):

Al-Ghamdi A.M. ◽

El-Zohri M

Keyword(s):

Dry Weight ◽

Soluble Carbohydrates ◽

Wheat Crop ◽

Aqueous Extracts ◽

Wild Oat ◽

Culture Experiment ◽

Allelopathic Potential ◽

Root Extracts ◽

Wheat Germination ◽

Radical Length

We investigated the phytotoxicity of desert cotton (Aerva javanica) extracts on wild oat and wheat. Aqueous extracts from A. javanica roots, leaves and inflorescences collected from Jeddah and Al-Baha regions, Saudi Arabia were used. Generally, the allelopathic potential of water extracts of A. javanica collected from Jeddah were more in inhibitory to wild oat germination and seedlings growth than those from Al-Baha. In both regions, root extracts were inhibitory to wild oat followed by leaves and inflorescences extracts. All test aqueous extracts of both regions did not inhibit the wheat germination or seedlings growth.Whreas, the wild oat germination was reduced by root extracts 58.62 %, 28.62 % leaves extracts : 32.72 %, 17.72 % and inflorescences extract 28.11 %, 12.13 % by in plants samples collected from Jeddah and Al-Baha, respectively. Wild oat radical length was inhibited by root extracts 53.27 %, 32.84 % leaves 42.35 %, 9.63 % and inflorescences extracts 22.64 %, 16.75 % in case of Jeddah and Al-Baha plants, respectively. In pot culture experiment, all treatments markedly reduced the plant dry weight and soluble carbohydrates, proteins and free amino acids contents in wild oat. The differences in the allelopathic potentials of studied A. javanica extracts were related to the qualitative variations in their phytochemicals constituents. Our results showed that A. javanica extracts could be safely used to control wild oat growth in wheat fields after more detsaled research..

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Wild oat control in ryegrass for seed production

Proceedings of the New Zealand Weed and Pest Control Conference ◽

10.30843/nzpp.1974.27.8914 ◽

1974 ◽

Vol 27 ◽

pp. 67-71 ◽

Cited By ~ 1

Author(s):

F C. Allen ◽

T.J. Smallridge ◽

G.W. Bourdot

Keyword(s):

Seed Production ◽

Wild Oat

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THE ROLE OF PHOSPHATIDYLINOSITOL-3-KINASE IN CARCINOGENESIS

Problems in oncology ◽

10.37469/0507-3758-2017-63-4-545-556 ◽

2017 ◽

Vol 63 (4) ◽

pp. 545-556

Author(s):

Natalya Oskina ◽

Aleksandr Shcherbakov ◽

Maksim Filipenko ◽

Nikolay Kushlinskiy ◽

L. Ovchinnikova

Keyword(s):

Genetic Disease ◽

Intracellular Signaling ◽

Somatic Mutations ◽

Pi3k Pathway ◽

Genetic Alterations ◽

Phosphatidylinositol 3 Kinase ◽

Intracellular Signaling Pathway ◽

Metabolic Activities ◽

Carcinogenic Process

Currently it is established that cancer is a genetic disease and that somatic mutations are the initiators of the carcinogenic process. The PI3K/AKT/mTOR pathway is an important intracellular signaling pathway regulating the cell growth and metabolic activities. Aberrant activation of the PI3K pathway is commonly observed in many different cancers. In this review we analyze the genetic alterations of PI3K pathway in a variety of human malignancies and discuss their possible implications for diagnosis and therapy.

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