Natural Antimicrobial Agents for Food Biopreservation

The antiphytopathogenic effects of the crude methanol extract of Cladophora glomerata (Lin.) Kützing (Cladophoraceae) which isolated from Al Rashidiya region at north of Baghdad was investigated against two type of plant fungi (Pythium altimum and Rhizoctonia solani) which causes damping off disease where isolated from covered cucumber field in Al-Alyosifia region. Hot methanol extract showed antifungal activity against the two species of fungi in different concentrations(10,25,50 mg/ml) of extract to Cladophora glomerata as percentage inhibition (51.63 ,72.8 ,83.71) and (56.18 ,77.41 ,100)comparing with Pythium altimum and Rhizoctonia solani respectively .primary detection of active compounds showed that macroalgae (Cladophora glomerata) containing flavonoids,alkaloids, phenols and tannins. Our findings suggest the possibility of using the Cladophora glomerata as a novel source of natural antimicrobial agents for pharmaceutical industries.

Download Full-text

Impact of Pre- and Post–Harvest Applications of Natural Antimicrobial Products on Apple and Pear Soft Rot Disease

International Journal of Phytopathology ◽

10.33687/phytopath.004.03.1329 ◽

2016 ◽

Vol 4 (3) ◽

pp. 105-119

Author(s):

Abdelradi T. Bakeer ◽

Khaled Elbanna ◽

Sameh A. Elnaggar

Keyword(s):

Antibacterial Activity ◽

Plant Extracts ◽

Antimicrobial Agents ◽

Soft Rot ◽

Natural Antimicrobial ◽

Soft Rot Disease ◽

Post Harvest ◽

Rot Disease ◽

Bacillus Strains

Three natural antibacterial compounds including bacteriocin like substance (BLS) produced from lactic acid bacteria (LAB), ethanolic extract of propolis (EEP), and nine plant extracts were evaluated against soft rot Bacillus strains. Testing in vivo these compounds were evaluated to control pear and apple soft rot disease. Among eight BLS tested, BLS of LAB2, LAB105 and LAB 107 exhibited the highest antibacterial activity as indicated by the formation of clear inhibition zone. Propolis extracts exhibited significant antibacterial activity against all tested soft rot Bacillus strains and it was noticed that the antibacterial activity was concentration dependent. Among nine plant extracts tested, extracts of Eucalyptus globulus and Psidium guajava exhibited the highest antibacterial activity. All tested antibacterial products significantly decreased apple and pear soft rot severity caused by Bacillus altitudinis compared to untreated control. The highest reduction percentage of soft rot severity was recorded for EEP followed by BLS from LAB and plant extracts tested, respectively. Combined pre-and post-harvest treatments of apple and pear with antimicrobial compounds proved to be more effective in reducing the soft rot severity and improved the physical and chemical properties of fruits during storage in both years of the study. The natural antimicrobial agents used in this study were promising compounds, since it seems to be more safe, economical and great potential for extending the shelf life and improve the quality of fruits. Therefore, the application of these compounds in the control of apple and pear soft rot could be advantageous for consumers, producers, and the environment.

Download Full-text

Tackling Antibiotic Resistance with Compounds of Natural Origin: A Comprehensive Review

Biomedicines ◽

10.3390/biomedicines8100405 ◽

2020 ◽

Vol 8 (10) ◽

pp. 405 ◽

Cited By ~ 1

Author(s):

Francisco Javier Álvarez-Martínez ◽

Enrique Barrajón-Catalán ◽

Vicente Micol

Keyword(s):

Antimicrobial Agents ◽

New Technologies ◽

Protein Biosynthesis ◽

Natural Compounds ◽

Network Pharmacology ◽

Resistant Bacteria ◽

Drug Resistant ◽

Antimicrobial Compounds ◽

Natural Antimicrobial ◽

Drug Resistant Bacteria

Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are an invaluable source of antimicrobial compounds. The antimicrobial activity of the most representative natural products of animal, bacterial, fungal and plant origin are reviewed in this paper. Their activity against drug-resistant bacteria, their mechanisms of action, the possible development of resistance against them, their role in current medicine and their future perspectives are discussed. Electronic databases such as PubMed, Scopus and ScienceDirect were used to search scientific contributions until September 2020, using relevant keywords. Natural compounds of heterogeneous origins have been shown to possess antimicrobial capabilities, including against antibiotic-resistant bacteria. The most commonly found mechanisms of antimicrobial action are related to protein biosynthesis and alteration of cell walls and membranes. Various natural compounds, especially phytochemicals, have shown synergistic capacity with antibiotics. There is little literature on the development of specific resistance mechanisms against natural antimicrobial compounds. New technologies such as -omics, network pharmacology and informatics have the potential to identify and characterize new natural antimicrobial compounds in the future. This knowledge may be useful for the development of future therapeutic strategies.

Download Full-text