Critical Role of ABCG2 in ALA-Photodynamic Diagnosis and Therapy of Human Brain Tumor

2015 ◽  
pp. 197-216 ◽  
Author(s):  
Toshihisa Ishikawa ◽  
Yoshinaga Kajimoto ◽  
Yutaka Inoue ◽  
Yoji Ikegami ◽  
Toshihiko Kuroiwa
Keyword(s):  
Brain Tumor ◽  
Human Brain ◽  
Critical Role ◽  
Photodynamic Diagnosis ◽  
Human Brain Tumor ◽  
Diagnosis And Therapy

scholarly journals Regulation of Aminopeptidase A in Human Brain Tumor Vasculature: Evidence for a Role of Transforming Growth Factor-β

2000 ◽  
Vol 80 (6) ◽  
pp. 973-980 ◽  
Author(s):  
Lucienne Juillerat-Jeanneret ◽  
Sylvia Lohm ◽  
Marie-France Hamou ◽  
Florence Pinet
Keyword(s):  
Brain Tumor ◽  
Growth Factor ◽  
Human Brain ◽  
Transforming Growth Factor ◽  
Tumor Vasculature ◽  
Transforming Growth Factor Β ◽  
Human Brain Tumor ◽  
Aminopeptidase A

Possible Role of The Tumor Suppressor Gene Retinoblastoma (Rb1) In Human Brain Tumor Development

2007 ◽  
Vol 14 (3) ◽  
pp. 72-82 ◽  
Author(s):  
Mathivanan Jothi ◽  
Rohini Keshava ◽  
Mohan L Gope ◽  
Rajalakshmi Gope
Keyword(s):  
Brain Tumor ◽  
Tumor Suppressor ◽  
Human Brain ◽  
Tumor Suppressor Gene ◽  
Tumor Development ◽  
Suppressor Gene ◽  
Human Brain Tumor

Human Brain Tumor Detection Using CPW Fed UWB Vivaldi Antenna

2019 ◽  
Author(s):  
Liton Chandra Paul ◽  
Md Nur Hossain ◽  
Md. Munjure Mowla ◽  
Md. Zulfiker Mahmud ◽  
Rezaul Azim ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Human Brain ◽  
Tumor Detection ◽  
Human Brain Tumor ◽  
Vivaldi Antenna

scholarly journals Magnetic Resonance Microscopy at 14 Tesla and Correlative Histopathology of Human Brain Tumor Tissue

PLoS ONE ◽  
2011 ◽  
Vol 6 (11) ◽  
pp. e27442 ◽  
Author(s):  
Ana Gonzalez-Segura ◽  
Jose Manuel Morales ◽  
Jose Manuel Gonzalez-Darder ◽  
Ramon Cardona-Marsal ◽  
Concepcion Lopez-Gines ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Magnetic Resonance ◽  
Human Brain ◽  
Tumor Tissue ◽  
Magnetic Resonance Microscopy ◽  
Human Brain Tumor

Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors

1994 ◽  
Vol 81 (1) ◽  
pp. 69-77 ◽  
Author(s):  
Takao Nakagawa ◽  
Toshihiko Kubota ◽  
Masanori Kabuto ◽  
Kazufumi Sato ◽  
Hirokazu Kawano ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Matrix Metalloproteinases ◽  
Brain Tumors ◽  
Human Brain ◽  
Tumor Cells ◽  
Tumor Invasion ◽  
Gelatinolytic Activity ◽  
Normal Brain ◽  
Tissue Inhibitor Of Metalloproteinases ◽  
Human Brain Tumor

✓ The role of matrix metalloproteinases (MMP's) and their inhibitor, tissue inhibitor of metalloproteinases-1 (TIMP-1), in human brain tumor invasion was investigated. Gelatinolytic activity was assayed via gelatin zymography, and four MMP's (MMP-1, MMP-2, MMP-3, and MMP-9) and TIMP-1 were immunolocalized in human brain tumors and in normal brain tissues using monoclonal antibodies. The tissue was surgically removed from 44 patients: glioblastoma (five cases), anaplastic astrocytoma (six cases), astrocytoma (four cases), metastatic tumor (six cases), neurinoma (10 cases), meningioma (10 cases), and normal brain tissue (three cases). Glioblastomas, anaplastic astrocytomas, and metastatic tumors showed high gelatinolytic activity and positive immunostaining for MMP's; TIMP-1 was also expressed in these tumors, but some tumor cells were negative for the antibody. Astrocytomas had low gelatinolytic activity and the tumor cells showed no immunoreactivity for MMP's and TIMP-1. Although neurinomas and meningiomas had only moderate proteinase activity and exhibited positive immunoreactivity for MMP-9, intense expression of TIMP-1 was simultaneously observed in these tumor cells. These findings suggest that MMP's play an important role in human brain tumor invasion, probably due to an imbalance between the production of MMP's and TIMP-1 by the tumor cells.

scholarly journals Creation of an NCI comparative brain tumor consortium: informing the translation of new knowledge from canine to human brain tumor patients

2016 ◽  
Vol 18 (9) ◽  
pp. 1209-1218 ◽  
Author(s):  
Amy K. LeBlanc ◽  
Christina Mazcko ◽  
Diane E. Brown ◽  
Jennifer W. Koehler ◽  
Andrew D. Miller ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Human Brain ◽  
Tumor Patients ◽  
Human Brain Tumor ◽  
New Knowledge

scholarly journals Microglia induces Gas1 expression in human brain tumor-initiating cells to reduce tumorigenecity

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Susobhan Sarkar ◽  
Candice C. Poon ◽  
Reza Mirzaei ◽  
Khalil S. Rawji ◽  
Walter Hader ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Human Brain ◽  
Tumor Initiating Cells ◽  
Human Brain Tumor ◽  
Brain Tumor Initiating Cells
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