Mirena® (Levonorgestrel intrauterine system): A successful novel drug delivery option in contraception

2009 ◽  
Vol 61 (10) ◽  
pp. 808-812 ◽  
Author(s):  
Susan Rose ◽  
Angela Chaudhari ◽  
C. Matthew Peterson
Keyword(s):  
Drug Delivery ◽  
System A ◽  
Novel Drug

A Novel Drug Delivery System: A Biodegradable Gel for the Treatment of Inner Ear Diseases

2004 ◽  
Vol 131 (2) ◽  
pp. P260-P260 ◽  
Author(s):  
Tsuyoshi Endo ◽  
Takayuki Nakagawa ◽  
Tomoko Kita ◽  
Tae Soo Kim ◽  
Fukuichiro Iguchi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Inner Ear ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ear Diseases ◽  
System A ◽  
Novel Drug Delivery System ◽  
Novel Drug

scholarly journals An Overview of Therapeutic Applications

2017 ◽  
pp. 366-390
Author(s):  
Sandeep Waghulde ◽  
Pravin Naik
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pharmacological Action ◽  
The Body ◽  
Traditional System ◽  
System A ◽  
Target Organs ◽  
Novel Drug Delivery System ◽  
Novel Drug

Over the last few years' great advances have been made on the development drug delivery systems for different purposes for targeting the diseased conditions. Novel drug delivery originates from polymers or associated with some devices is generally related with the emergence of novel characteristics. These changes are what eventually comprise the value of drug delivery system and Novel drug delivery system. Novel properties become existed without making new materials. Novel drug delivery system comparable to traditional system, following Targeted Drug Delivery System (TDDS) is also called targeting drug system. A new drug delivery system makes the drugs densely gather pathological-change structures, and has an improved healing effect and less toxic side effects. The drugs can improve the strength of pharmacological action and reduce the bad effect all over the body, for they release in the target organs.

Chitosan Nanoparticles as a Novel Drug Delivery System: A Review Article

2020 ◽  
Vol 21 (15) ◽  
pp. 1613-1624
Author(s):  
Sina M. Matalqah ◽  
Khalid Aiedeh ◽  
Nizar M. Mhaidat ◽  
Karem H. Alzoubi ◽  
Yasser Bustanji ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Chitosan Nanoparticles ◽  
Chemical Properties ◽  
Delivery Systems ◽  
Natural Polymers ◽  
System A ◽  
Naturally Occurring ◽  
Mucoadhesive Polymer ◽  
Novel Drug

Natural polymers, particularly polysaccharide, have been used as drug delivery systems for a variety of therapeutic agents such as peptides, proteins, vaccines, DNA, and drugs for parenteral and non-parenteral administration. Chitosan, the second most abundant naturally occurring polysaccharide after cellulose, is a biocompatible and biodegradable mucoadhesive polymer that is extensively used in the preparation of nanoparticles (NPs). Chitosan NPs loaded with drugs were found to be stable, permeable and bioactive. In this review, the importance of chitosan and its derivatives in drug delivery is illustrated, different methods of preparation of chitosan and chitosan derivatives NPs and their physio- chemical properties are addressed. Moreover, the desirable characteristics of successful NPs based drug delivery systems, as well as the pharmaceutical applications of these NPs are also clearly explored.

scholarly journals Functionality and Acceptance of the EsoCap System—A Novel Film-Based Drug Delivery Technology: Results of an In Vivo Study

Pharmaceutics ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 828
Author(s):  
Christoph Rosenbaum ◽  
Michael Grimm ◽  
Julius Krause ◽  
Adrian Rump ◽  
Rebecca Kessler ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Polymer Film ◽  
Esophageal Mucosa ◽  
Esophageal Diseases ◽  
System A ◽  
Mri Scans ◽  
Novel Drug ◽  
First Time ◽  
Delivery Technology

There are no methods for specific local application of active substances to the mucosa of the esophagus to treat eosinophilic esophagitis or other esophageal diseases. This publication describes the principal in vivo functionality and acceptance of a novel modular drug delivery concept, called EsoCap system, by 12 healthy volunteers. For the first time, the EsoCap system enables targeted placement on the esophageal mucosa of a mucoadhesive polymer film. Acceptance was determined by means of a standardized questionnaire after administration and functionality of the device by MRI scans. Two different setups of the EsoCap system were tested: one setup with a density of 0.4 g/cm3 and one with a density of 1.0 g/cm3. Acceptability of the dosage form was also confirmed in addition to functionality, by measuring the applied film length. It was found that acceptance of the variant with the higher density was significantly better. This novel drug delivery technology could enable a targeted, local and long-lasting therapy of the esophagus for the first time, depending on the polymer film used.

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