Impact of Body Mass Index on the One-Year Clinical Outcome of Patients Undergoing Multivessel Revascularization With Sirolimus-Eluting Stents (from the Arterial Revascularization Therapies Study Part II)††Conflicts of interest: Magdaleen Pieters, Kristel Wittebols, and Hans-Peter Stoll are employees of Cordis Corporation. Joost Daemen received a consultancy fee for his scientific contribution.

Abstract The objective of this research was to determine the body perception (BP) of preschoolers and compare it with the one reported by their parents. A total of 48 preschoolers participated (Mage = 5 years, SD = 0.5), 21 boys, 27 girls, and their parents (47 fathers and 48 mothers). The children were weighed and measured, also they answered the instrument Seven Figures of Collins (SFC) and seven questions about food, beauty and health. The parents answered the Body Image Questionnaire, the Stunkard Figures, as well as the SFCs to identify the real (RF) and ideal figure(IF) of their children. When children described themselves, they mostly referred the normal figure, coinciding with their parents. A very small proportion of preschoolers perceived themselves with obesity (around 29-30%); while any parent identified their children with obesity. 50% of preschoolers chose thinner silhouettes than their body mass index (BMI), but not emaciated. For RF, most parents chose normal weight for boys and light overweight for girls; for IF parents chose, for both sexes, the one with light overweight. In conclusion, the preschool BP disagreed between reality and perception, regardless of their BMI and gender. The parents also did not have an adequate BP for their children. Resumen El objetivo de esta investigación fue conocer la percepción corporal (PC) de preescolares y compararla con la que sus padres tienen de ellos. Participaron 48 preescolares (Medad = 5 años, DE = 0.5), 21 niños y 27 niñas, y sus padres (47 papás y 48 mamás). Los niños fueron pesados y medidos, contestaron el instrumento Siete Figuras de Collins (SFC) y, con relación a éste, siete preguntas sobre alimentación, belleza y salud. A los padres se les aplicó el Cuestionario de Imagen Corporal, las Figuras de Stunkard, además de las SFC para que identificaran la figura real (FR) e ideal (FI) de sus hijos. Para describirse, los preescolares refirieron mayormente la figura normopeso, coincidiendo con sus padres. Fue mínima la proporción de preescolares que se percibieron con obesidad (presente en 29-30%); mientras que ningún padre la identificó en sus hijos. El 50% de los preescolares eligió siluetas más delgadas a su índice de masa corporal (IMC), pero no emaciadas. Como FR, la mayoría de los padres eligió la normopeso para los niños y con sobrepeso ligero para las niñas; como FI eligieron, para ambos sexos, aquélla con sobrepeso ligero. En conclusión, la PC del preescolar discrepó entre la real y la percibida, independientemente de su IMC y sexo. Los padres tampoco tuvieron una adecuada PC de sus hijos.

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BODY MASS INDEX AND ALBUMIN LEVELS ARE ASSOCIATED WITH PULMONARY FUNCTION PARAMETERS IN PEDIATRIC SUBJECTS WITH CYSTIC FIBROSIS

Revista Paulista de Pediatria ◽

10.1590/1984-0462/;2019;37;4;00016 ◽

2019 ◽

Vol 37 (4) ◽

pp. 414-418

Author(s):

Miriam Isabel Souza dos Santos Simon ◽

Gabriele Carra Forte ◽

Paulo José Cauduro Marostica

Keyword(s):

Body Mass Index ◽

Cystic Fibrosis ◽

Pulmonary Function ◽

Body Mass ◽

Univariate Analysis ◽

Cross Sectional Study ◽

Forced Expiratory Volume ◽

Tertiary Referral Hospital ◽

Cross Sectional ◽

One Year

ABSTRACT Objective: To evaluate the association of body mass index (BMI) and albumin with pulmonary function in cystic fibrosis (CF) pediatric subjects. Methods: This is a cross-sectional study with clinically stable CF’s subjects. Clinical (pulmonary function) and nutritional evaluation (body mass index and albumin) were performed. Univariate analysis was performed using simple linear correlations. Regression analysis was performed using an exit level of p<0.05. Results: Seventy-eight CF’s subjects (mean age 12.8±3.8 years) with mean albumin 4.2±0.4 mg/dL, predicted forced expiratory volume in 1 second (FEV1%) 80.8±22.6 and BMI median percentile 51.2 (1.3-97.7). In the multiple regression models, albumin, age and BMI percentile were associated with pulmonary function. Subjects with lower than 25 BMI percentile had 12.2% lower FEV1%. An albumin increase of 0.1 mg was associated with 2.7% increase in predicted FEV1%, and one year increase in age was associated with reduction in 1.2% of predicted FEV1%. Conclusions: BMI percentile, albumin and age were independently associated with predicted FEV1% in a tertiary referral hospital.

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Impact of pretransplant body mass index on the clinical outcome after allogeneic hematopoietic SCT

Bone Marrow Transplantation ◽

10.1038/bmt.2014.178 ◽

2014 ◽

Vol 49 (12) ◽

pp. 1505-1512 ◽

Cited By ~ 38

Author(s):

S Fuji ◽

K Takano ◽

T Mori ◽

T Eto ◽

S Taniguchi ◽

...

Keyword(s):

Body Mass Index ◽

Clinical Outcome ◽

Body Mass

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Circulating Microparticles and Risk of Venous Thromboembolism.

Blood ◽

10.1182/blood.v114.22.3987.3987 ◽

2009 ◽

Vol 114 (22) ◽

pp. 3987-3987

Author(s):

Paolo Bucciarelli ◽

Emanuele Previtali ◽

Ida Martinelli ◽

Andrea Artoni ◽

Serena M Passamonti ◽

...

Keyword(s):

Body Mass Index ◽

Venous Thromboembolism ◽

Body Mass ◽

Plasma Levels ◽

Conflicts Of Interest ◽

Factor V Leiden ◽

Control Group ◽

Dependent Manner ◽

Healthy Controls ◽

Increased Risk

Abstract Abstract 3987 Poster Board III-923 Background Microparticles (MPs) are circulating, submicroscopic fragments (<1 μm of diameter) of membrane-bound cytoplasm that shed from the surface of an activated or apoptotic cell and play a role in coagulation, inflammation, cell remodelling and proliferation. There is increasing evidence that MPs are involved in thrombosis, but whether or not they are an independent risk factor for venous thromboembolism (VTE) is not established. Aim of the study To investigate the association between high plasma levels of MPs and risk of VTE Patients and Methods In a case-control study, 186 patients with a first episode of VTE (deep venous thrombosis and/or pulmonary embolism) and 418 healthy controls were included. MPs were analyzed by flow cytometry with a gate defined by a 1 μm beads and using APC-Annexin V together with FITC anti-CD41 or FITC anti-CD142 antibodies in order to identify platelet MPs (MP-Plts) and MPs exposing tissue factor (MP-TF), respectively. MPs levels were expressed as number/μL. Results Patients had significantly higher median plasma levels of both MPs-Plts and MPs-TF than controls [1942 vs 1519 (p<0.0001) and 579 vs 454 (p<0.0001)]. Higher median levels of MP-Plts and MP-TF were found in 41 patients who underwent blood sampling within 6 months from VTE than in those sampled later [2114 vs 1694 (p=0.086) and 652 vs 543 (p=0.120)]. Sex, age, body mass index and factor VIII plasma levels had no influence on MPs levels, as well as the use of oral contraceptives (this latter evaluated only in controls). In the whole study population, carriership of thrombophilia (antithrombin, protein C or protein S deficiency, factor V Leiden, prothrombin G20210A, antiphospholipid antibodies, hyperhomocysteinemia or combined abnormalities) had higher levels of MP-Plts and MP-TF than non-carriers [1907 vs 1565 (p=0.002) and 532 vs 468 (p=0.011)]. The odds ratio (OR) for VTE, adjusted for sex, age, body mass index and thrombophilia was 2.5-fold higher in individuals with MPs plasma levels >95th percentile of the control group (3633/μL for MPs-Plts and 1113/μL for MPs-TF) than in those with MPs levels ≤95th percentile [for MPs-Plts: OR=2.59 (95%CI 1.23 – 5.45); for MPs-TF: OR=2.38 (1.15 – 4.92)]. The risk increased in a dose-dependent manner for both MPs-Plts and MPs-TF, particularly above the 75th percentile of the distribution in controls. The exclusion of patients whose MPs levels were measured within 6 months from VTE (in order to avoid the possible effect of the acute phase on MPs measurements), did not change the results [adjusted OR: 2.63 (1.18 – 5.89) for MPs-Plts and 2.36 (1.10 – 5.19) for MPs-TF]. The Table shows the relative risks of VTE associated with the presence or absence of high MPs levels and thrombophilia. Individuals with MPs >95th percentile or thrombophilia alone had a 2 to 3-fold increased risk of VTE, whereas those with both MPs-Plts >95th percentile and thrombophilia had a 9-fold increased risk of VTE. This synergistic effect was confirmed also for MPs-TF and remained after the exclusion of patients whose blood sample was collected within 6 months from VTE [OR 7.72 (1.68-35.4) for MP-Plts and 8.14 (2.08-31.8) for MP-TF]. Conclusions Plasma levels of MPs are significantly higher in patients with VTE than in healthy controls. MPs levels >95th percentile are associated with a 2.5-fold increased risk of VTE. There is a synergistic interaction between high levels of MPs and thrombophilia on VTE risk. Disclosures: No relevant conflicts of interest to declare.

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