scholarly journals A Saccharomyces cerevisiae RC016-based feed additive reduces liver toxicity, residual aflatoxin B1 levels and positively influences intestinal morphology in broiler chickens fed chronic aflatoxin B1-contaminated diets

2020 ◽  
Vol 6 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Valeria Poloni ◽  
Alejandra Magnoli ◽  
Analía Fochesato ◽  
Andrea Cristofolini ◽  
Matías Caverzan ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Aflatoxin B1 ◽  
Broiler Chickens ◽  
Liver Toxicity ◽  
Intestinal Morphology ◽  
Feed Additive

scholarly journals Evaluation of the Combined Use of Saccharomyces Cerevisiae and Aspergillus Oryzae with Phytase Fermentation Products on Growth, Inflammatory, and Intestinal Morphology in Broilers

Animals ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 1051 ◽  
Author(s):  
Wen Yang. Chuang ◽  
Wei Chih. Lin ◽  
Yun Chen. Hsieh ◽  
Chung Ming. Huang ◽  
Shen Chang. Chang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Saccharomyces Cerevisiae ◽  
Mrna Expression ◽  
Aspergillus Oryzae ◽  
Mononuclear Cells ◽  
Intestinal Morphology ◽  
Soy Sauce ◽  
Feed Additive ◽  
Fermentation Products ◽  
Fermented Products

Saccharomyces cerevisiae and Aspergillus oryzae are both ancient probiotic species traditionally used as microbes for brewing beer and soy sauce, respectively. This study investigated the effect of adding these two probiotics with phytase fermentation products to the broilers diet. Fermented products possess protease and cellulase, and the activities were 777.1 and 189.5 U/g dry matter (DM) on S. cerevisiae fermented products (SCFP) and 190 and 213.4 U/g DM on A. oryzae fermented products (AOFP), respectively. Liposaccharides stimulated PBMCs to produce nitric oxide to 120 μmol. Both SCFP and AOFP reduced lipopolysaccharides stimulated peripheral blood mononuclear cells (PBMCs) nitric oxide release to 40 and 60 μmol, respectively. Nevertheless, in an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, SCFP and AOFP also increased the survival rate of lipopolysaccharides stimulated PBMCs by almost two-fold compared to the negative control. A total of 240 broilers were divided into four groups as Control, SCFP 0.1% (SCFP), SCFP 0.05% + AOFP 0.05% (SAFP), and AOFP 0.1% (AOFP) groups, respectively. Each group had 20 broilers, and three replicate pens. The results showed that the addition of SCFP, SAFP, and AOFP groups did not affect the growth performances, but increased the jejunum value of villus height and villus: crypt ratio on SAFP and AOFP groups compared to the control and SCFP groups. Furthermore, adding SCFP, SAFP, and AOFP significantly reduced the number of Clostridium perfringens in ileum chyme. SCFP, SAFP, and AOFP significantly reduced the amount of interleukin-1β, inducible nitric oxide synthases, interferon-γ, and nuclear factor kappa B mRNA expression in PBMCs, especially in the AOFP group. In summary, all the SCFP, SAFP, and AOFP groups can be suggested as a functional feed additive since they enhanced villus: crypt ratio and decreased inflammation-related mRNA expression, especially for AOFP group in broilers.

Detoxification of aflatoxin B1 in broiler chickens by a triple-action feed additive

2021 ◽  
pp. 1-11
Author(s):  
Hongwei Guo ◽  
Juan Chang ◽  
Ping Wang ◽  
Qingqiang Yin ◽  
Chaoqi Liu ◽  
...  
Keyword(s):  
Aflatoxin B1 ◽  
Broiler Chickens ◽  
Feed Additive

scholarly journals The Effect of Probiotic Supplementation on Performance and the Histopathological Changes in Liver and Kidneys in Broiler Chickens Fed Diets with Aflatoxin B1

Toxins ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 112 ◽  
Author(s):  
Katarzyna Śliżewska ◽  
Bożena Cukrowska ◽  
Stefania Smulikowska ◽  
Joanna Cielecka-Kuszyk
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Aflatoxin B1 ◽  
Soybean Meal ◽  
Broiler Chickens ◽  
Control Diet ◽  
Histopathological Changes ◽  
Negative Effects ◽  
Probiotic Supplementation ◽  
Probiotic Preparation ◽  
Broiler Feed

The aim of the study was to investigate the toxic effects of aflatoxin B1 (AFB1) and efficacy of a probiotic preparation containing L. reuteri, L. plantarum, L. pentosus, L. rhamnosus and L. paracasei and Saccharomyces cerevisiae yeasts to ameliorate their effects in broiler chickens. A total of 168 one-day-old female Ross 308 broilers were randomly allocated to six groups. Three wheat and soybean meal-based diets were prepared: Control diet and diets contaminated with 1 or 5 mg/kg AFB1 supplied in moldy wheat. All diets were unsupplemented or supplemented with probiotic, cold pelleted and fed from 1 to 35 day of life. Feeding diet with 1 mg AFB1/kg did not affect performance, but a diet with 5 mg AFB1 resulted in a significant reduction of feed intake and BWG, both diets induced liver and kidneys enlargement. The probiotic supplementation of the diets partially ameliorated those negative effects and resulted in a significant increase of AFB1 excretion. It was accompanied by the reduced level of AFB1 residues in the liver from 8.9 to 3.7 and from 11.8 to 5.9 µg/kg, in kidneys from 7.9 to 2.5 and from 13.7 to 4.1 µg/kg in birds fed the less and more contaminated diets, respectively. AFB1 exposure caused many severe histopathological changes in the liver and kidneys of broilers, probiotic supplementation significantly reduced the changes of these organs. It may be concluded that the probiotic supplementation can be used to alleviate the negative effects of contamination of broiler feed with AFB1 on bird health and product security.

scholarly journals Influence of Enzyme Supplementation in the Diets of Broiler Chickens Formulated with Different Corn Hybrids Dried at Various Temperatures

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 643
Author(s):  
Franciele C. N. Giacobbo ◽  
Cinthia Eyng ◽  
Ricardo V. Nunes ◽  
Cleison de Souza ◽  
Levy V. Teixeira ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Nutrient Digestibility ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Intestinal Morphology ◽  
Feed Conversion ◽  
Corn Hybrids ◽  
Positive Effects ◽  
Cecal Microbiota ◽  
Enzyme Supplementation

We evaluated the influence of enzymatic supplementation on the growth performance and cecal microbiota of broilers. A total of 2160 1-day-old male chicks were used in a 3 × 2 × 2 factorial arrangement (three corn hybrids, two drying temperatures −80 and 110 °C, with or without the inclusion of an enzymatic blend (amylase, xylanase, and protease) (20 birds/pen, n = 9). For all performance and digestibility parameters, we observed, in general, isolated effects of the corn hybrids and drying temperature. Birds that received the enzymatic blend in the diet showed better weight gain from 1 to 21 days (d) and better digestibility coefficients of nutrients at 42 d. Birds fed diets with corn dried at 80 °C showed a better feed conversion ratio from 1 to 42 d. At 21 d of age, enzymatic supplementation had positive effects on jejunum morphology. Enzyme supplementation increased the abundance of the phylum Tenericutes, class Bacilli and Mollicutes, reduced Clostridia, and increased the abundances of the families Lactobacillaceae, Anaeroplasmataceae, and O_RF39;F. In conclusion, the addition of amylase, xylanase, and protease led to a better nutrient digestibility, performance, and intestinal morphology. In addition, enzyme supplementation changed the diversity, composition, and predicted function of the cecal microbiota at d 21.

scholarly journals Application of Selenium Conjugated to Animal Protein in Laying Hens’ Diet for the Production of Selenium-Enriched Eggs

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1224
Author(s):  
Kai Qiu ◽  
Youbiao Ma ◽  
Uchechukwu Edna Obianwuna ◽  
Jing Wang ◽  
Haijun Zhang ◽  
...  
Keyword(s):  
Laying Hens ◽  
Egg Quality ◽  
Intestinal Morphology ◽  
Feed Additive ◽  
Control Group ◽  
Organic Selenium ◽  
Positive Effects ◽  
Enhanced Production ◽  
Immune Capacity ◽  
Biochemical Indices

The current experiment was conducted to investigate the application effects of selenium conjugated to insect protein (SCIP) in the production of selenium-enriched eggs. A total of 450 laying hens were randomly assigned to five dietary groups, each group consisting of six replicates. Hens in the control group received a diet without selenium supplementation, whereas hens in the other four groups received diets supplemented with either 1, 2, 5, or 10 mg/kg of selenium from SCIP. The productive performance, egg quality, antioxidant and immune capacity, biochemical indices, intestinal morphology, and oviduct health of laying hens were evaluated. The results showed that the supplementation of organic selenium provided by SCIP in the diets of laying hens enhanced performance and egg quality without any toxicity effect, even at the 10 mg/kg inclusion level. A level of 2 mg/kg of selenium provided by SCIP in diets tentatively improved the serum antioxidant and immune capacity, intestinal development, and oviduct health of laying hens in a conspicuous manner. Hence, the biosafety and positive effects of SCIP as a feed additive supplement in laying hens’ diet have been demonstrated with the enhanced production of safe and selenium-enriched eggs.

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