scholarly journals Anti-Parasitic Activity of Myristica Fragrans Houtt. Essential Oil Against Toxoplasma Gondii Parasite

2012 ◽  
Vol 2 ◽  
pp. 92-96 ◽  
Author(s):  
Suthagar Pillai ◽  
Roziahanim Mahmud ◽  
Wei Cai Lee ◽  
Shanmugapriya Perumal
Keyword(s):  
Toxoplasma Gondii ◽  
Essential Oil ◽  
Myristica Fragrans ◽  
Parasitic Activity ◽  
Myristica Fragrans Houtt

scholarly journals Utilization of Nutmeg (Myristica fragrans Houtt.) Seed Hydrodistillation Time to Produce Essential Oil Fractions with Varied Compositions and Pharmacological Effects

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 565 ◽  
Author(s):  
Mohamed A. Ibrahim ◽  
Charles L. Cantrell ◽  
Ekaterina A. Jeliazkova ◽  
Tess Astatkie ◽  
Valtcho D. Zheljazkov
Keyword(s):  
Plasmodium Falciparum ◽  
Essential Oil ◽  
Seed Oil ◽  
Antimalarial Activity ◽  
Chemical Compositions ◽  
Pharmacological Effects ◽  
Substantial Variation ◽  
Myristica Fragrans ◽  
Oil Fractions ◽  
Myristica Fragrans Houtt

The intent of this study was to utilize distillation timeframes (DT) of nutmeg (Myristica fragrans) essential oil (EO) to generate fractions with differential chemical compositions and bioactivity. Ten fractions were captured at the following distillation timeframes: 0.0–0.5, 0.5–1.0, 1.0–2.5, 2.5–5.0, 5.0–10, 10–30, 30–60, 60–90, 90–120, and 120–240 min. In addition, a control EO was collected from a straight 0–240 min non-stop distillation. ANOVA and advanced regression modeling revealed that the produced EO fractions possess substantial variation in the concentration of potentially desired compounds. The concentrations (%) of α-phellandrene, 3-carene, p-cymene, limonene, α-thujene, α-pinene, camphene, sabinene, β-pinene, and myrcene decreased, while the concentrations (%) of α-terpinene, γ-terpinene, terpinolene, and myristicin increased in later DT fractions. Nutmeg EO showed some antimalarial activity against Plasmodium falciparum D6, but did not exhibit significant antifungal activity. In general, nutmeg seed oil yields increased with an increase of DT. These results may be utilized by industries using nutmeg EO.

scholarly journals Larvicidal Activity of Essential Oils from the Leaves and Fruits of Nutmeg (Myristica fragrans Houtt) Against Aedes aegypti (Diptera: Culicidae)

2016 ◽  
Vol 4 (7) ◽  
pp. 552
Author(s):  
Anne Carolina ◽  
Maman Maman
Keyword(s):  
Essential Oil ◽  
Aedes Aegypti ◽  
Larvicidal Activity ◽  
Steam Distillation ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Myristica Fragrans ◽  
Leaf Oil ◽  
Myristica Fragrans Houtt ◽  
Fruit Oil

The aim of this research was to examine the larvicidal activity of essential oil (EO) extracted from nutmeg (Myristica fragrans Houtt) leaves and fruits by steam distillation, and to analyze its chemical compounds. The EO yield of nutmeg leaves and fruits collected from the same tree was 0.66% and 0.30%, respectively. Larvicidal tests with the EO were carried out against Aedes aegypti (L.) (Diptera: Culicidae). The concentrations of nutmeg EO used for the larvicidal assay were 50, 100, 150, 200, and 250 μg/mL. The results showed that fruit oil was more toxic than the leaf oil. LC50 values of leaf and fruit EOs were 133.8 and 110.1 µg/mL, respectively. The chromatogram of GC-MS showed that the chemical components in nutmeg leaf and fruit EOs were dominated by α-pinene, sabinene, β-pinene, delta-3-carene, limonene, β-phellandrene, α-terpinolene, linalool, safrole, croweacin, and myristicin.

scholarly journals A Review on Chemical Composition, Bioactivity, and Toxicity of Myristica fragrans Houtt. Essential Oil

2021 ◽  
pp. 304-313
Author(s):  
Mega Ferdina Warsito
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Chemical Compounds ◽  
Volatile Oil ◽  
Natural Medicine ◽  
Myristica Fragrans ◽  
Biological Potency ◽  
Myristica Fragrans Houtt ◽  
Nutmeg Essential Oil

Myristica fragrans Houtt., commonly known as nutmeg, is an Indonesian indigenous dioecious evergreen tree which contains 5-15% volatile oil. The oil is usually produced from the seed or mace.  Nutmeg oil has been extensively utilized in aromatherapy, natural medicine, and the perfume industry. This article provides an overview of the chemical compounds, biological potency, and toxic effects of nutmeg essential oil compiled from recent literature (2000–2020). Nutmeg oil mainly comprises monoterpenes and phenylpropanoids. Several reports on gas chromatography-mass spectrophotometry analysis of nutmeg oil showed that there were 27–38 chemical constituents detected at various concentrations. Many secondary metabolites of nutmeg oil reported to show biological activities that possibly substantiate its utilization in natural medicine. Numerous studies reported the biological activities of this volatile oil such as antioxidant, analgesic, antiinflammation, anticonvulsant, antibacterial, antiparasitic, insecticidal, and anticancer activity. But large intake of nutmeg oil could cause intoxication which is shown through symptoms in cardiovascular, central nervous system, anticholinergic, and local effects in the stomach. These symptoms are mainly attributed to the effect of myristicin, safrole, and elemicin overdose. This updated review paper intends to attract more attention to nutmeg oil and its potential to be developed into a medicinal product for the prophylaxis and therapy of diseases.

COMPOSITION AND ANTIFUNGAL ACTIVITY OF THE BRAZILIAN MYRISTICA FRAGRANS HOUTT ESSENTIAL OIL

2011 ◽  
Vol 31 (2) ◽  
pp. 197-202 ◽  
Author(s):  
VÂNIA MARIA MOREIRA VALENTE ◽  
GULAB NEWANDRAM JHAM ◽  
ONKAR DEV DHINGRA ◽  
ION GHIVIRIGA
Keyword(s):  
Antifungal Activity ◽  
Essential Oil ◽  
Myristica Fragrans ◽  
Myristica Fragrans Houtt

Characterization and Optimization of Microwave Assisted Process for Extraction of Nutmeg (Myristica fragrans Houtt.) Mace Essential Oil

2018 ◽  
Vol 21 (4) ◽  
pp. 895-904 ◽  
Author(s):  
Nukasani Sagarika ◽  
M.V. Prince ◽  
Anjineyulu Kothakota ◽  
R. Pandiselvam ◽  
R. Sreeja ◽  
...  
Keyword(s):  
Essential Oil ◽  
Microwave Assisted ◽  
Myristica Fragrans ◽  
Myristica Fragrans Houtt

scholarly journals ISOLATION OF ESSENSIAL OIL OF NUTMEG (Myristica fragrans Houtt) and ANTIOXIDANT ACTIVITY TEST WITH DPPH

2018 ◽  
Vol 18 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Binawati Ginting ◽  
Ratna Maira ◽  
Mustanir . ◽  
Hira Helwati ◽  
Lydia Septa Desiyana ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Essential Oil ◽  
Essential Oils ◽  
Flavonoid Compound ◽  
Piper Nigrum ◽  
Chemical Compositions ◽  
Green Pepper ◽  
Myristica Fragrans ◽  
Phenolic Constituents ◽  
Myristica Fragrans Houtt

The essential oil of the nutmeg plant (Myristica fragrans Houtt) has been obtained from roots, bark, fruit, mace and seeds using Stahl steam distillation. Each essential oil have tested for antioxidant activity with DPPH. Antioxidant activity of essential oil from each nutmeg plant to DPPH with concentration 25, 50 and 100 ppm. Each essential oil did not show strong antioxidant activity but the result of nutmeg isolation had strong antioxidant activity with IC50 that was 80,555 ppm. Based on GC-MS analysis of essential oil of nutmeg isolate obtained myristicin compound with 96.52% area and time Retention 22.127. Myristicin is one of the main components of essential oils of nutmeg plants that play an important role as antioxidants. Keywords: Nutmeg plant (Myristica fragrans Houtt), Essential Oil, DPPH, Antioxidant radicalsREFERENCES Suryanti, Siti. 2014. Metabolit Sekunder Pada Tanaman dan Fungsinya. http://seputarduniasains.blogspot.com Diakses tanggal 2 juni 2015. Gupta, A. 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