Controllable doping of Fe atoms into MoS2 nanosheets towards peroxidase-like nanozyme with enhanced catalysis for colorimetric analysis of glucose

Background: Laguna-ONhE is an application for the colorimetric analysis of optic nerve images, which topographically assesses the cup and the presence of haemoglobin. Its latest version has been fully automated with five deep learning models. In this paper, perimetry in combination with Laguna-ONhE or Cirrus-OCT was evaluated. Methods: The morphology and perfusion estimated by Laguna ONhE were compiled into a “Globin Distribution Function” (GDF). Visual field irregularity was measured with the usual pattern standard deviation (PSD) and the threshold coefficient of variation (TCV), which analyses its harmony without taking into account age-corrected values. In total, 477 normal eyes, 235 confirmed, and 98 suspected glaucoma cases were examined with Cirrus-OCT and different fundus cameras and perimeters. Results: The best Receiver Operating Characteristic (ROC) analysis results for confirmed and suspected glaucoma were obtained with the combination of GDF and TCV (AUC: 0.995 and 0.935, respectively. Sensitivities: 94.5% and 45.9%, respectively, for 99% specificity). The best combination of OCT and perimetry was obtained with the vertical cup/disc ratio and PSD (AUC: 0.988 and 0.847, respectively. Sensitivities: 84.7% and 18.4%, respectively, for 99% specificity). Conclusion: Using Laguna ONhE, morphology, perfusion, and function can be mutually enhanced with the methods described for the purpose of glaucoma assessment, providing early sensitivity.

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Carbon–nitrogen conjugate-composited Cu1.8S with enhanced peroxidase-like activity for the colorimetric detection of hydrogen peroxide and glutathione

Analytical Methods ◽

10.1039/d1ay00166c ◽

2021 ◽

Vol 13 (14) ◽

pp. 1706-1714

Author(s):

Nianlu Li ◽

Mingquan Zhu ◽

Zhenyu Feng ◽

Wenhui Lu ◽

Jing Chen ◽

...

Keyword(s):

Hydrogen Peroxide ◽

Colorimetric Detection ◽

Colorimetric Analysis ◽

Higher Sensitivity

In this work, cystine–glucose Maillard conjugates were composited with Cu1.8S microspheres (Cu1.8S–cgmc) to achieve higher sensitivity for the colorimetric analysis.

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Enhanced Dielectric Screening and Photoluminescence from Nanopillar-Strained MoS2 Nanosheets: Implications for Strain Funneling in Optoelectronic Applications

ACS Applied Nano Materials ◽

10.1021/acsanm.1c01368 ◽

2021 ◽

Author(s):

Mounika Vutukuru ◽

Hossein Ardekani ◽

Zhuofa Chen ◽

Ryan L. Wilmington ◽

Kenan Gundogdu ◽

...

Keyword(s):

Mos2 Nanosheets ◽

Dielectric Screening ◽

Optoelectronic Applications

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MoS2–Nanosheets-Based Catalysts for Photocatalytic CO2 Reduction: A Review

ACS Applied Nano Materials ◽

10.1021/acsanm.1c00990 ◽

2021 ◽

Author(s):

Shreya Singh ◽

Arindam Modak ◽

Kamal Kishore Pant ◽

Apurba Sinhamahapatra ◽

Pratim Biswas

Keyword(s):

Co2 Reduction ◽

Mos2 Nanosheets

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Assessment of Mini-Tablets Coating Uniformity as a Function of Fluid Bed Coater Inlet Conditions

Pharmaceutics ◽

10.3390/pharmaceutics13050746 ◽

2021 ◽

Vol 13 (5) ◽

pp. 746

Author(s):

Magdalena Turk ◽

Rok Šibanc ◽

Rok Dreu ◽

Maja Frankiewicz ◽

Małgorzata Sznitowska

Keyword(s):

Coating Layer ◽

Spectrophotometric Analysis ◽

Material Distribution ◽

Spray Chamber ◽

Colorimetric Analysis ◽

Swirl Generator ◽

Coating Uniformity ◽

Fluid Bed ◽

Inlet Conditions

This study concerned the quality of mini-tablets’ coating uniformity obtained by either the bottom spray chamber with a classical Wurster distributor (CW) or a swirl distributor (SW). Mini-tablets with a diameter of 2.0, 2.5, and 3.0 mm were coated with hypromellose using two different inlet air distributors as well as inlet airflow rates (130 and 156 m3/h). Tartrazine was used as a colorant in the coating layer and the coating uniformity was assessed by spectrophotometric analysis of solutions obtained after disintegration of the mini-tablets (n = 100). Higher uniformity of coating material distribution among the mini-tablets was observed in the case of SW distributor, even for the biggest mini-tablets (d = 3.0 mm), with an RSD no larger than 5.0%. Additionally, coating thickness was evaluated by colorimetric analysis (n = 1000), using a scanner method, and expressed as a hue value. A high correlation (R = 0.993) between inter-tablet variability of hue and UV-Vis results was obtained. Mini-tablets were successfully coated in a fluid bed system using both a classical Wurster distributor as well as a swirl generator. However, regardless of the mini-tablets’ diameter, better film uniformity was achieved in the case of a distributor with a swirl generator.

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