Evaluation of the influence of granulation processing parameters on the granule properties and dissolution characteristics of a modified release drug

2011 ◽  
Vol 22 (2) ◽  
pp. 245-252 ◽  
Author(s):  
D.T. Ring ◽  
J.C.O. Oliveira ◽  
A. Crean
Keyword(s):  
Processing Parameters ◽  
Modified Release ◽  
Release Drug ◽  
Granule Properties

Hydrogels for modified-release drug delivery systems

2021 ◽  
Vol 28 ◽  
Author(s):  
Aleksandra Zielińska ◽  
Piotr Eder ◽  
Lucas Rannier ◽  
Juliana C. Cardoso ◽  
Patrícia Severino ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Drug Delivery Systems ◽  
Search Strategy ◽  
Delivery Systems ◽  
Global Market ◽  
Modified Release ◽  
Safety And Efficacy ◽  
Area Of Interest ◽  
Release Drug

Abstract: Hydrogels for the modified-release drug delivery systems is a continuously growing area of interest for the pharmaceutical industry. According to the global market, the use of polymers in this area is projected to reach $31.4 million by 2027. This review discusses the recent advances and perspectives of hydrogel in drug delivery systems for oral, parenteral, nasal, topical, and ophthalmic. The search strategy did in January 2021, and it conducted an extensive database to identify studies published from January 2010 to December 2020.We described the main characteristic of the polymers to obtain an ideal hydrogel for a specific route of administration and the formulations that was a highlight in the literature. It concluded that the hydrogels are a set useful to decrease the number of doses, side effects, promote adhesion of patient and enhances the bioavailability of the drugs improving the safety and efficacy of the treatment.

Scientific and Regulatory Considerations in Solid Oral Modified Release Drug Product Development

2016 ◽  
Vol 18 (6) ◽  
pp. 1406-1417 ◽  
Author(s):  
Min Li ◽  
Sanna Sander ◽  
John Duan ◽  
Susan Rosencrance ◽  
Sarah Pope Miksinski ◽  
...  
Keyword(s):  
Product Development ◽  
Drug Product ◽  
Modified Release ◽  
Release Drug

scholarly journals Corticosteroid Replacement Therapy

2021 ◽  
Author(s):  
Michael C. Onyema
Keyword(s):  
Clinical Trials ◽  
Adrenal Insufficiency ◽  
Replacement Therapy ◽  
20Th Century ◽  
Hormone Replacement ◽  
Modified Release ◽  
Future Treatment ◽  
Release Drug ◽  
Treatment Considerations ◽  
Special Circumstances

The advent of synthetic corticosteroids in the 20th century provided a vital breakthrough in the management of adrenal insufficiency. In this chapter we review the main indications and guidance for appropriate hormone replacement and also look into the management of therapy during special circumstances. For decades hydrocortisone has remained the cornerstone for glucocorticoid replacement but we explore the alternatives including recently introduced modified-release drug preparations and the future treatment considerations currently undergoing research and pre-clinical trials.

scholarly journals Gelucire: A versatile polymer for modified release drug delivery system

2018 ◽  
Vol 4 (1) ◽  
pp. 102-108 ◽  
Author(s):  
Kahnu Charan Panigrahi ◽  
Ch. Niranjan Patra ◽  
Goutam Kumar Jena ◽  
Debashish Ghose ◽  
Jayashree Jena ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Modified Release ◽  
Release Drug
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