Dietary medium chain fatty acids from coconut oil have little effects on postprandial plasma metabolite profiles in rainbow trout (Oncorhynchus mykiss)

Aquaculture ◽  
2014 ◽  
Vol 420-421 ◽  
pp. 24-31 ◽  
Author(s):  
L. Luo ◽  
M. Xue ◽  
C. Vachot ◽  
I. Geurden ◽  
S. Kaushik
Keyword(s):  
Fatty Acids ◽  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Coconut Oil ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Metabolite Profiles ◽  
Plasma Metabolite ◽  
Chain Fatty Acids

Effects of calcium salts of medium-chain fatty acids on plasma metabolite and hormone concentrations in early lactating dairy cows

2014 ◽  
Vol 54 (10) ◽  
pp. 1699
Author(s):  
T. Sugino ◽  
A. Tateno ◽  
G. Ueno ◽  
K. Kawashima ◽  
T. Okimura ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Dairy Cows ◽  
Control Group ◽  
Calcium Salts ◽  
Treatment Groups ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Lactating Dairy Cows ◽  
Plasma Metabolite ◽  
Chain Fatty Acids

To elucidate the effects of medium-chain fatty acids (MCFA) on milk production and plasma metabolite and hormone concentrations in early lactating dairy cows, 10 multiparous Holstein dairy cows were randomly assigned to two dietary treatment groups after parturition. One group was fed a diet supplemented with calcium salts of MCFA (MCFA-Ca) for 8 weeks after parturition, while the other group was fed the same diet without the supplement (control). MCFA-Ca, containing 60% caprylic acid and 40% capric acid, was added to a total mixed ration (TMR) at 1.5% of the dietary dry matter (DM). Cows were offered the TMR ad libitum. DM intake, daily gain in bodyweight, milk yield, milk fat content and milk protein content did not differ between the two treatment groups. The MCFA-Ca diet decreased plasma glucose and triglyceride concentrations (P < 0.05), while plasma concentrations of total and free cholesterols tended to increase (P < 0.10). Plasma ghrelin was maintained at a higher concentration (P < 0.05) in cows fed the MCFA-Ca diet than in the control group. Relative to the control diet, the MCFA-Ca diet decreased plasma insulin concentration (P < 0.05) and numerically increased plasma glucagon concentration, resulting in a lower insulin : glucagon ratio (P < 0.05). In conclusion, plasma metabolite and hormone concentrations were affected by the MCFA-Ca diet, suggesting that MCFA-Ca supplementation may change endocrine functions and nutrient metabolism in early lactating cows, ultimately resulting in an enhanced catabolic state.

scholarly journals Physiological and Reproductive Responses of Domyati Ducks to Different Dietary Levels of Coconut Oil as a Source of Medium-Chain Fatty Acids during Laying Period

2020 ◽  
Vol 10 (3) ◽  
pp. 485-492
Author(s):  
K. H. El-Kholy ◽  
A. I. A. Ghonim ◽  
M. A. Ahmed ◽  
Hoda A. Gad ◽  
Mervat N. Ghazal ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Coconut Oil ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

scholarly journals Candida auris is rendered non-viable by medium-chain fatty acids

2021 ◽  
Author(s):  
Kalynne R Green ◽  
Kearney T. W. Gunsalus ◽  
Magdia De Jesus
Keyword(s):  
Fatty Acids ◽  
Coconut Oil ◽  
Decanoic Acid ◽  
Antifungal Drugs ◽  
Candida Auris ◽  
Biofilm Growth ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
New Strategy ◽  
Chain Fatty Acids

The medium-chain fatty acids, octanoic and decanoic acid, found in coconut oil, were fungistatic and decanoic acid was fungicidal against a panel of Candida auris strains, during both planktonic and biofilm growth. The strains were from all four major geographic clades, and some were resistant to several classes of antifungal drugs. These compounds are safe, natural products and could provide a new strategy for skin decolonization and environmental decontamination.

Antimicrobial Effects of Virgin Coconut Oil and Its Medium-Chain Fatty Acids onClostridium difficile

2013 ◽  
Vol 16 (12) ◽  
pp. 1079-1085 ◽  
Author(s):  
Michael Shilling ◽  
Laurie Matt ◽  
Evelyn Rubin ◽  
Mark Paul Visitacion ◽  
Nairmeen A. Haller ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Coconut Oil ◽  
Virgin Coconut Oil ◽  
Antimicrobial Effects ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Chain Fatty Acids

scholarly journals Assessing the effects of medium-chain fatty acids and fat sources on PEDV infectivity

2019 ◽  
Vol 4 (2) ◽  
pp. 1051-1059 ◽  
Author(s):  
Roger A Cochrane ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Charles R Stark ◽  
Marut Saensukjaroenphon ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Chemical Treatment ◽  
Palm Kernel ◽  
Coconut Oil ◽  
Palm Kernel Oil ◽  
Diarrhea Virus ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Kernel Oil ◽  
Chain Fatty Acids

Abstract: The overall objective of this study was to compare the efficacy of medium-chain fatty acids (MCFA) to other common fat sources to minimize the risk of porcine epidemic diarrhea virus (PEDV) cross-contamination in a pig bioassay. Treatments were feed with mitigants inoculated with PEDV after application and were: 1) positive control with no chemical treatment; 2) 0.325% commercially available formaldehyde-based product; 3) 1% blend of 1:1:1 caproic (C6), caprylic (C8), and capric acids (C10) and applied with an aerosolizing nozzle; 4) treatment 3 applied directly into the mixer without an aerosolizing nozzle; 5) 0.66% caproic acid; 6) 0.66% caprylic acid; 7) 0.66% capric acid; 8) 0.66% lauric acid; 9) 1% blend of 1:1 capric and lauric acids; 10) 0.3% commercially available dry C12 product; 11) 1% canola oil; 12) 1% choice white grease; 13) 2% coconut oil; 14) 1% coconut oil; 15) 2% palm kernel oil; 16) 1% palm kernel oil; 17) 1% soy oil and four analysis days (0, 1, 3, and 7 post inoculation) as well as 1 treatment of PEDV-negative feed without chemical treatment. There was a treatment × day interaction (P &lt; 0.002) for detectable PEDV RNA. The magnitude of the increase in Ct value from d 0 to 7 was dependent upon the individual treatments. Feed treated with individual MCFA, 1% MCFA blend, or commercial-based formaldehyde had fewer (P &lt; 0.05) detectable viral particles than all other treatments. Commercial-based formaldehyde, 1% MCFA, 0.66% caproic, 0.66% caprylic, and 0.66% capric acids had no evidence of infectivity 10-d old pig bioassay, while there was no evidence the C12 commercial product or longer chain fat sources inhibited PEDV infectivity. Interestingly, pigs given the coconut oil source with the highest composition of caprylic and capric only showed signs of infectivity on the last day of bioassay. These data suggest some MCFA have potential for reducing post feed manufacture PEDV contamination.

scholarly journals A Half-Truth is Not the Whole Truth: The AHA Position on Saturated Fat

KIMIKA ◽  
2017 ◽  
Vol 28 (2) ◽  
pp. 48-54
Author(s):  
Fabian M. Dayrit
Keyword(s):  
Fatty Acids ◽  
American Heart ◽  
Saturated Fat ◽  
Coconut Oil ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Metabolic Properties ◽  
The 1960S ◽  
Chain Fatty Acids

This second in this series of papers will present the biases in the American Heart Association’s 2017 Presidential Advisory with respect to saturated fat. Although important differences in the metabolic properties of specific SFA have been known since the 1960s, the AHA still considers all SFA as one group having the same properties. There is abundant research available that supports the designation of C6 to C12 fatty acids as medium-chain fatty acids (MCFA). This is particularly relevant to coconut oil, which is made up of about 65% MCFA. Ignoring the evidence, AHA simply labels coconut oil as SFA. The AHA promotes half-truths, not the whole truth.

scholarly journals LAURINE FATTY ACIDS, MEDIUM FATTY ACIDS AND TRIGLYCERIDES, HYPERLIPIDEMIA, RESISTANCE TO INSULIN, PREVENTION OF ATHEROSCLEROSIS AND ATEROMATOSIS

2019 ◽  
Vol 64 (2) ◽  
pp. 68-77
Author(s):  
V. N. Titov ◽  
G. A. Ivanov ◽  
A. M. Antonov
Keyword(s):  
Fatty Acids ◽  
Cardiovascular System ◽  
Ketone Bodies ◽  
Coconut Oil ◽  
Simultaneous Increase ◽  
Type I ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids

Although the biochemistry of the positive effects of medium-chain fatty acids (FA) and triglycerides (TG) of the same name in vivo is not fully understood, food enriched with medium-chain LC and the same TG is effective in patients with type I diabetes, insulin resistance syndrome and in neurodegenerative pathology. Lauric C12 LC is half the FA in coconut oil. Residents of southeast Asia with constant use of coconut oil, have a low level of diseases of the cardiovascular system in the population. With a regulatory intake with food C12:0 laurin FA formed moderate ketosis and neuroprotective effect. Unlike long-chain LC, medium-chain TG cells are not deposited either in visceral fat cells, or in insulin-dependent adipocytes. Medium-chain fatty acids rapidly oxidize mitochondria; the formation of acetyl-CoA cells is used to form ketone bodies, activating thermogenesis in orange and brown adipocytes. Experiments with animals and observations in the clinic showed that taking medium-chain TG with food is more physiological than long-chain oils. This significantly increases the level of cholesterol in high-density lipoproteins. Food enriched with medium chain TG is optimal for increasing the ketone content in blood plasma, cerebrospinal fluid without limiting the carbohydrate content in food. The formation of excess ketone bodies by cells can be achieved by activating the metabolic transformations of medium-chain FAs, without fasting and preserving carbohydrates in food. Coconut oil has a positive effect on the cardiovascular system, preventing the formation of atherosclerosis and atheromatosis. Effective in the prevention of the pathology of the cardiovascular system is a decrease in food amounts of palmitic acid, an increase in oleic acid, polyene FA with a simultaneous increase in the proportion of medium-chain FA.

Nutritional Values and Health Protective Properties Of Coconut Oil

2020 ◽  
Vol 3 (2) ◽  
pp. 1-12
Author(s):  
Jansen Silalahi
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Coconut Oil ◽  
Medium Chain Triglycerides ◽  
Nutritional Values ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Long Chain Triglycerides ◽  
Long Chain ◽  
Chain Fatty Acids

Chemically, fat or oil is a mixture of triacylglycerol molecules, in which glycerol esterified with three fatty acids. Fatty acid is a monocarboxilic acid containing even number of carbon atom started from 4 to 22. Based on the length of fatty acid in triacylglycerol, fats and oils can be classified into two groups; medium chain triglycerides and long chain triglycerides. Coconut oil belongs to medium chain triglycerides oil because it’s fatty acids consist mostly of medium chain fatty acids (C4:0 to C12:0) and dominated by lauric acid (C12:0), hence usually called as lauric oil. In the year of 1950s, coconut oil was claimed that saturated fats, including coconut oil, could increase blood total cholesterol and hence is atherogenic, while unsaturated fats decrease total cholesterol. However, in 1990s, coconut oil was found to be different from the other saturated oils. Coconut oil composed of medium chain fatty acids with high amount of lauric acid. Coconut oil is metabolized differently from long chain triglycerides saturated oil, and therefore coconut oil has numerous beneficial nutritional values and health promotion. Consumption of food rich in medium chain fatty acids reduces the level of body fat and the decrease the risk of heart disease, diabetes, increase mother’s milk quality and active as potential antibacterial agent.  

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