The Effect of Mechanical Leg Alignment on Cartilage Restoration With and Without Concomitant High Tibial Osteotomy

2020 ◽  
Vol 36 (8) ◽  
pp. 2204-2214
Author(s):  
Jakob Ackermann ◽  
Gergo Merkely ◽  
Dillon Arango ◽  
Alexandre Barbieri Mestriner ◽  
Andreas H. Gomoll
2021 ◽  
Vol 10 (2) ◽  
pp. 368
Author(s):  
Mylène P. Jansen ◽  
Susanne Maschek ◽  
Ronald J. van Heerwaarden ◽  
Simon C. Mastbergen ◽  
Wolfgang Wirth ◽  
...  

High tibial osteotomy (HTO) and knee joint distraction (KJD) are joint-preserving treatments that unload the more affected compartment (MAC) in knee osteoarthritis. This post-hoc study compares two-year cartilage-thickness changes after treatment with KJD vs. HTO, and identifies factors predicting cartilage restoration. Patients indicated for HTO were randomized to KJD (KJDHTO) or HTO treatment. Patients indicated for total knee arthroplasty received KJD (KJDTKA). Outcomes were the MRI mean MAC cartilage thickness and percentage of denuded bone area (dABp) change two years after treatment, using radiographic joint space width (JSW) as the reference. Cohen’s d was used for between-group effect sizes. Post-treatment, KJDHTO patients (n = 18) did not show significant changes. HTO patients (n = 33) displayed a decrease in MAC cartilage thickness and an increase in dABp, but an increase in JSW. KJDTKA (n = 18) showed an increase in MAC cartilage thickness and JSW, and a decrease in dABp. Osteoarthritis severity was the strongest predictor of cartilage restoration. Kellgren–Lawrence grade ≥3 showed significant restoration (p < 0.01) after KJD; grade ≤2 did not. Effect sizes between severe KJD and HTO patients were large for MAC MRI cartilage thickness (d = 1.09; p = 0.005) and dABp (d = 1.13; p = 0.003), but not radiographic JSW (d = 0.28; p = 0.521). This suggests that in knee osteoarthritis patients with high disease severity, KJD may be more efficient in restoring cartilage thickness.


2019 ◽  
Vol 7 (3_suppl2) ◽  
pp. 2325967119S0019
Author(s):  
Joseph N. Liu ◽  
David R. Christian ◽  
Avinesh Agarwalla ◽  
Grant H. Garcia ◽  
Michael L. Redondo ◽  
...  

Objectives: Varus deformity of the knee predisposes patients to chondral and meniscal pathology of the medial compartment. Young patients with symptomatic chondral defects of the medial femoral with varus alignment often undergo concomitant opening wedge high tibial osteotomy (HTO) and cartilage restoration including allograft transplantation (OCA). Limited information is available regarding return to sporting activities after combined HTO and osteochondral allograft transplantation (OCA). Methods: All patients who underwent concomitant HTO and OCA by a single surgeon for medial knee pain due to a focal chondral defect of the medial femoral condyle were retrospectively identified through a prospectively collected data base. The primary indication for HTO was varus malalignment ≥ 5 degrees. At final follow-up, patients completed a subjective sports questionnaire, the Marx activity scale, a pain visual analog scale (VAS), a Single Assessment Numerical Evaluation (SANE), and a satisfaction questionnaire. Patients were excluded for having undergone any concomitant procedure other than cartilage restoration or < 2 years of follow-up. Results: Of 39 concomitant HTO and OCA patients, 28 (71.8%) were available for follow-up at an average 6.07 +/- 4.09 years (range: 2-13 years). The average age at the time of surgery was 35.8 +/- 8.2 years, and 22 patients (78.6%) of patients were male. Four patients (14.3%) also underwent a concomitant medial meniscal allograft transplantation. Nearly all patients had undergone a prior ipsilateral knee surgery (26 patients, 92.8%). Reoperation was performed in 14 patients (50.0%) by the time of final follow-up for persistent symptoms: 6 patients received a meniscal debridement/meniscectomy, 2 patients received a total knee replacement, 1 patient received a unicompartmental knee arthroplasty, 4 patients underwent hardware removal, and 1 patient underwent autologous chondrocyte implantation of a new defect. Of the 22 patients who participated in sports within 3 years prior to their HTO + OAG, 18 patients (67.9%) returned to sport at an average of 11.4 +/- 6.4 months following operative management; however, only 35.7% of patients were able to return to their pre-injury level. Additionally, 60.7% of patients reported being satisfied or extremely satisfied with their return to sport activity. The most common reasons for discontinuing sports were: to prevent further damage (62.5%), persistent pain (54.2%), persistent swelling (33.3%), and fear of further injury (20.8%). Specific sports had high direct rates of return to sport: golf (100%), cross-fit/high-intensity (83.3%), cycling (88.9%), heavy-weightlifting (100%), swimming (60%), running (44.4%) (Figure 1). Conclusion: In a young and active population, concomitant HTO and OA provides a high rate of return to sport 11.4 months postoperatively, although only 35.7% could return to preinjury level or better. Additionally, at an average of 6.07 years following the index procedure, 60.7% of patients were satisfied regarding their sports and activities. When indicated, concomitant HTO and OCA may provide good results in young and active patients who wish to resume sports and physical activities.


2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Grégoire Micicoi ◽  
Raghbir Khakha ◽  
Kristian Kley ◽  
Adrian Wilson ◽  
Simone Cerciello ◽  
...  

Abstract The joint line convergence angle (JLCA) has a normal range between 0° to 2°, which increases in magnitude depending on the severity and stage of osteoarthritis in the knee. The JLCA represents the interaction of the intra-articular deformity arising from the osteoarthritis and the surrounding soft tissue laxity. Therefore, the JLCA has become a vital parameter in analysing the long leg alignment views for corrective planning before osteotomy surgery. Recent studies have considered the influence on how the preoperative JLCA is measured and its influence on achieving accurate postoperative desired correction in high tibial osteotomy surgery. The JLCA also reflects the influence of soft tissue laxity in a lower limb malalignment and many surgeons encourage it to be taken into account to avoid non physiological correction and/or overcorrection with negatively impacted postoperative patient outcome. This present review addressed how to obtain an accurate preoperative measurement of the JLCA, its influence on postoperative deformity analysis and how to reduce errors arising from an elevated preoperative JLCA. We have proposed a formula to help determine the value to subtract from the planned correction in order to avoid an overcorrection when performing a corrective osteotomy. Level of clinical evidence IV, narrative review.


2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Haitao Zhang ◽  
Yinuo Fan ◽  
Rui Wang ◽  
Wenjun Feng ◽  
Jinlun Chen ◽  
...  

Abstract Background The purpose of this study is to comprehensively analyze the global application trend of high tibial osteotomy (HTO) and identify promising research hotspots of HTO based on bibliometrics and visual analysis. Methods Publications (articles and reviews) related to HTO from 2001 to 2020 were retrieved from the Web of Science Core Collection database (WOSCC). The country, institution, year, author, journal, average citations per item, H index, title, abstract, keywords of publication, and the top 10 cited articles were extracted and analyzed in detail. The VOSviewer software was used to analyze theco-occurrence of keywords to predict the hotspots of HTO. Results A total of 1883 articles were included. In the past 20 years, the number of HTO articles has shown an increasing trend in general. The top 3 countries (the USA, Germany, and South Korea) accounted for 49.547% of all articles published. The USA has the largest number of publications. The University of Western Ontario is the largest contributor. The Knee Surgery Sports Traumatology Arthroscopy is the most influential journal. Professors Saito T and Imhoff AB are the leading scholars who made great achievements in the HTO field. The research direction can be divided into the following 5 clusters: "prognosis and outcome", "HTO combined with cartilage restoration techniques", "animal experimental research", "study on bone union and plate fixation at osteotomy", and "surgical technique research". Conclusion In terms of the trend of previous years, an increasing number of literatures related to HTO will be published in the future. The USA is a world leader in the field of HTO. South Korea presented great potential in this area. HTO combined with cartilage restoration techniques, postoperative prognosis and outcome, and surgical technique research may be the future hotspots in the field of HTO research.


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