Decentralized Vitamin C & D Dual Biosensor Chip: Toward Personalized Immune System Support

The benefits of natural honeybee products (e.g., honey, royal jelly, beeswax, propolis, beevenom and pollen) to the immune system are remarkable, and many of them are involved in the induction of antibody production, maturation of immune cells and stimulation of the immune system. The type of plants in the geographical area, climatic conditions and production method have a significantly influence on the nutritional quality of honey. However, this variability can influence consumer liking by the sensory attributes of the product. The aim of this work was to compare the most popular honeys from Poland in terms of nutritional value, organoleptic properties and antioxidant activity. In the study, five varieties of honey (honeydew, forest, buckwheat, linden and dandelion) from conventional and organic production methods were tested. The nutritional characteristics of honey samples included acidity, content of water, sugars, vitamin C, HMF and phenolics (total and flavonoids), while honey color, taste, aroma and consistency were investigated in the organoleptic characteristics. The antioxidant activity was determined in water- and ethanol-soluble honey extracts using DPPH and ORAC tests. The results showed that organoleptic and nutritional characteristics of popular Polish honeys differ significantly in relation to plant source and production method. The significant effect of honey variety on the content of HMF, saccharose and phenolics, as well as acidity and antioxidant capacity were noted. The impact of variety and variety × production method interaction was significant in the case of the content of vitamin C, glucose and fructose. A visible difference of buckwheat and forest honeys from other samples was observed. The highest content of total phenolics with antioxidant activity based on the SET mechanism was found in buckwheat honeys, while forest honeys were richer in flavonoids.

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TINOSPORA CORDIFOLIA: A MAGICAL WAND WITH IMMENSE MEDICINAL APPLICATIONS

PLANT ARCHIVES ◽

10.51470/plantarchives.2021.v21.no2.024 ◽

2021 ◽

Vol 21 (2) ◽

Author(s):

Akanksha Arora

Keyword(s):

Immune System ◽

Vitamin C ◽

Health Benefits ◽

Tinospora Cordifolia ◽

C Protein ◽

Bioactive Phytochemicals ◽

Anti Inflammatory ◽

Significant Health ◽

Hiv Aids

Tinospora cordifolia, a herb with a potential of boosting the immune system of a person is fully packed with nutrition be it carbohydrates, vitamin C, protein, fat, bioactive phytochemicals etc which one can have for relieving the person from illness and providing significant health benefits. When it comes to healthy herbs and plants Tinospora cordifolia never fails as a choice to cure the diseases and the symptoms associated with it. It helps in the treatment and management of diabetes, cancer, HIV-AIDS, toxicity from aflatoxins, osteoporosis, inflammation, leprosy, arthritis etc by the helps of various phytochemicals present in it. Alkaloids like Tinocordiside, Palmatine, Magnoflorine helps in cancer, syringin works as a great anti-allergen, magnoflorine as an anti-inflammatory etc.

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PENENTUAN KADAR VITAMIN C BEBERAPA JENIS CABAI (Capsicum sp.) DENGAN SPEKTROFOTOMETRI UV-VIS

Jurnal Kimia Riset ◽

10.20473/jkr.v3i1.8874 ◽

2018 ◽

Vol 3 (1) ◽

pp. 1

Author(s):

Lilis Rosmainar Tambunan ◽

Widia Ningsih ◽

Ni Putu Ayu ◽

Haula Nanda

Keyword(s):

Free Radicals ◽

Immune System ◽

Vitamin C ◽

Oxidative Damage ◽

Spectrophotometric Method ◽

Fruits And Vegetables ◽

Preliminary Test ◽

The Body ◽

Red Pepper ◽

Pepper Sample

Vitamin C is one of the nutrients that act as antioxidants and effectively overcome free radicals that can damage cells or tissues, including protecting the lens from oxidative damage caused by radiation. Vitamin C is widely found in fruits, and vegetables, one of them in chili. Vitamin C in chili has a function as a good antioxidant for the body (able to increase the immune system absorbed by calcium in the body. This study aims to determine the levels of vitamin C contained in some types of chili using UV-Vis spectrophotometry method and conduct a preliminary test. The highest levels of vitamin C obtained by using spectrophotometric method at 200 nm wavelength were on red curly pepper (50 g/100 g) and followed by chili jablay orange-red (38 g/100 g), green cayenne (29 g/100 g), red pepper large (22 g/100 g), and large green chili (9 g/100 g). While based on preliminary test it was found that all chilies contain saponins, as well as only large red pepper (sample 1) and red curly pepper (sample 4) containing flavonoids Keywords: capsicum, chilly, spectrophotometry

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High-dose vitamin C enhances cancer immunotherapy

Science Translational Medicine ◽

10.1126/scitranslmed.aay8707 ◽

2020 ◽

Vol 12 (532) ◽

pp. eaay8707 ◽

Cited By ~ 17

Author(s):

Alessandro Magrì ◽

Giovanni Germano ◽

Annalisa Lorenzato ◽

Simona Lamba ◽

Rosaria Chilà ◽

...

Keyword(s):

Immune System ◽

Vitamin C ◽

Clinical Evidence ◽

High Dose ◽

Dependent Manner ◽

Cancer Cell Growth ◽

Mutational Burden ◽

Cancer Types ◽

High Doses ◽

High Dose Vitamin

Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly unknown. Here, we show that a fully competent immune system is required to maximize the antiproliferative effect of VitC in breast, colorectal, melanoma, and pancreatic murine tumors. High-dose VitC modulates infiltration of the tumor microenvironment by cells of the immune system and delays cancer growth in a T cell–dependent manner. VitC not only enhances the cytotoxic activity of adoptively transferred CD8 T cells but also cooperates with immune checkpoint therapy (ICT) in several cancer types. Combination of VitC and ICT can be curative in models of mismatch repair–deficient tumors with high mutational burden. This work provides a rationale for clinical trials combining ICT with high doses of VitC.

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Effect of Dietary Supplementation of Vitamin C and Seeds of Achyranthes aspera on Growth, Digestive Enzyme Activities, Immune System and Lipid Peroxidation of Snow Trout Schizothorax richardsonii

Madridge Journal of Aquaculture Research & Development ◽

10.18689/mjard-1000105 ◽

2017 ◽

Vol 1 (1) ◽

pp. 24-30 ◽

Cited By ~ 1

Author(s):

Moses Rinchui Ngasainao ◽

Kjell J Nilssen ◽

Rina Chakrabarti

Keyword(s):

Lipid Peroxidation ◽

Immune System ◽

Vitamin C ◽

Enzyme Activities ◽

Digestive Enzyme ◽

Dietary Supplementation ◽

Achyranthes Aspera ◽

Snow Trout ◽

Digestive Enzyme Activities ◽

Schizothorax Richardsonii

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Determination of Vitamin C in Various Colours of Bell Pepper (Capsicum annuum L.) by Titration Method

ALCHEMY Jurnal Penelitian Kimia ◽

10.20961/alchemy.14.1.15738.164-178 ◽

2018 ◽

Vol 14 (1) ◽

pp. 164 ◽

Cited By ~ 3

Author(s):

Nerdy Nerdy

Keyword(s):

Immune System ◽

Vitamin C ◽

Human Body ◽

Bell Pepper ◽

Titration Method ◽

Metaphosphoric Acid ◽

Yellow Orange ◽

Different Color ◽

Different Levels

Vitamin C is needed by human body to improve the immune system and can be obtained from the bell pepper. Bell pepper has a different color according to the level of maturity, ranging from green, yellow, orange, and red. Differences in color also make possible differences in vitamin C content. The purpose of this study was to determine vitamin C levels in various colors of bell fruit. Measurement of vitamin C was done by titration method with metaphosphoric acid as the solvent and 2,6 dichloroindophenol as the standardized solution. The samples used were green bell pepper, yellow bell pepper, orange bell pepper, and red bell pepper taken from Gundaling, Berastagi, Karo, Sumatera Utara, 22152, Indonesia. The results show that vitamin C level in various colors of bell pepper respectively, for green bell pepper 16.52 mg vitamin C per 100 g green bell pepper; yellow bell pepper 159.61 vitamin C per 100 g yellow bell pepper; orange bell pepper 121.38 vitamin C per 100g orange bell pepper; red bell pepper 81.19 vitamin C per 100 g red bell pepper. These results indicate that different levels of bell pepper maturity have different vitamin C content.

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The Therapeutic Relevance of Vitamin E

Revista de Chimie ◽

10.37358/rc.19.10.7630 ◽

2019 ◽

Vol 70 (10) ◽

pp. 3711-3713

Author(s):

Lucretia Anghel ◽

Liliana Baroiu ◽

Adrian Beznea ◽

Gabi Topor ◽

Camelia Ana Grigore

Keyword(s):

Oxidative Stress ◽

Immune System ◽

Vitamin E ◽

Platelet Aggregation ◽

Vitamin C ◽

Active Form ◽

Alpha Tocopherol ◽

Mitochondrial Activity ◽

Metabolic Function ◽

Therapeutic Relevance

Maintaining cellular homeostasis in the context of its normal metabolic function is achieved by establishing the balance between its own antioxidant capacity and the level of harmful compounds resulting from the mitochondrial activity and the immune system. One of the antioxidants involved in this process is vitamin E with its most active form - alpha-tocopherol, which exerts its functions through vitamin C. The main functions of this antioxidant are: regulation of platelet aggregation, cellular signaling, antioxidation. The therapeutic relevance of vitamin E has increased due to the incrimination of oxidative stress as a link in the pathophysiology of many chronic diseases. Respectively, the role most targeted is that of antioxidant.

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