Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme

2009 ◽  
Vol 17 (15) ◽  
pp. 5414-5419 ◽  
Author(s):  
Kuo-Liang Su ◽  
Kuan-Yu Chang ◽  
Hui-Chih Hung
Author(s):  
S.M. Geyer ◽  
C.L. Mendenhall ◽  
J.T. Hung ◽  
E.L. Cardell ◽  
R.L. Drake ◽  
...  

Thirty-three mature male Holtzman rats were randomly placed in 3 treatment groups: Controls (C); Ethanolics (E); and Wine drinkers (W). The animals were fed synthetic diets (Lieber type) with ethanol or wine substituted isocalorically for carbohydrates in the diet of E and W groups, respectively. W received a volume of wine which provided the same gram quantity of alcohol consumed by E. The animals were sacrificed by decapitation after 6 weeks and the livers processed for quantitative triglycerides (T3), proteins, malic enzyme activity (MEA), light microscopy (LM) and electron microscopy (EM). Morphometric analysis of randomly selected LM and EM micrographs was performed to determine organellar changes in centrilobular (CV) and periportal (PV) regions of the liver. This analysis (Table 1) showed that hepatocytes from E were larger than those in C and W groups. Smooth endoplasmic reticulum decreased in E and increased in W compared to C values.


1991 ◽  
Vol 81 (4) ◽  
pp. 462-466 ◽  
Author(s):  
Maria Fabiana Drincovich ◽  
Alberto A. Iglesias ◽  
Carlos S. Andreo

Microbiology ◽  
1999 ◽  
Vol 145 (8) ◽  
pp. 1911-1917 ◽  
Author(s):  
James P. Wynn ◽  
Aidil bin Abdul Hamid ◽  
Colin Ratledge

FEBS Journal ◽  
2021 ◽  
Author(s):  
Dipon Kumar Mondal ◽  
Dhiman Sankar Pal ◽  
Mazharul Abbasi ◽  
Rupak Datta

2014 ◽  
Vol 893 ◽  
pp. 283-286
Author(s):  
Hong Ying Pei ◽  
Gui Jun Shen ◽  
Yu Du

A benefit of imprinted polymers is the possibility to prepare sorbents with selectivity pre-determined for a particular substance, or group of structural analogues. The application most close to a wider acceptance is probably that of solid phase extraction for clean-up of environmental and biological samples. The technique of molecularly imprinted polymers to solid phase extraction (MISPE) is performance and high selectively, compared with traditional sorbents. In this paper, the preparation and application of MIPs would be reviewed.


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