Disruption of the aldehyde dehydrogenase 2 gene increases the bone anabolic response to intermittent PTH treatment in an ovariectomized mouse model

Bone ◽  
2020 ◽  
Vol 136 ◽  
pp. 115370
Author(s):  
Kenji Kosugi ◽  
Takafumi Tajima ◽  
Kunitaka Menuki ◽  
Kayoko Furukawa Okuma ◽  
Kotaro Tokuda ◽  
...  
Keyword(s):  
Mouse Model ◽  
Aldehyde Dehydrogenase ◽  
Aldehyde Dehydrogenase 2 ◽  
Anabolic Response ◽  
Ovariectomized Mouse ◽  
Aldehyde Dehydrogenase 2 Gene ◽  
Intermittent Pth

scholarly journals The Defective Allele of Aldehyde Dehydrogenase 2 Gene is Associated with Favorable Postoperative Prognosis in Hepatocellular Carcinoma

2019 ◽  
Vol 10 (23) ◽  
pp. 5735-5743 ◽  
Author(s):  
Po-Han Huang ◽  
Ching-Chih Hu ◽  
Cheng-Hung Chien ◽  
Li-Wei Chen ◽  
Rong-Nan Chien ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Aldehyde Dehydrogenase ◽  
Aldehyde Dehydrogenase 2 ◽  
Postoperative Prognosis ◽  
Defective Allele ◽  
Aldehyde Dehydrogenase 2 Gene

scholarly journals Aldehyde Dehydrogenase 2 Gene Is a Risk Factor for Myocardial Infarction in Japanese Men.

2002 ◽  
Vol 25 (5) ◽  
pp. 677-681 ◽  
Author(s):  
Shuichi TAKAGI ◽  
Naoharu IWAI ◽  
Ryoko YAMAUCHI ◽  
Sunao KOJIMA ◽  
Shinji YASUNO ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Risk Factor ◽  
Aldehyde Dehydrogenase ◽  
Aldehyde Dehydrogenase 2 ◽  
Japanese Men ◽  
Aldehyde Dehydrogenase 2 Gene

scholarly journals Meta-Analysis of Aldehyde Dehydrogenase 2 Gene Polymorphism and Alzheimer's Disease in East Asians

2011 ◽  
Vol 38 (3) ◽  
pp. 500-506 ◽  
Author(s):  
Pan-Pan Hao ◽  
Yu-Guo Chen ◽  
Jia-Li Wang ◽  
Xing Li Wang ◽  
Yun Zhang
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Aldehyde Dehydrogenase ◽  
Meta Analysis ◽  
East Asian ◽  
Small Sample ◽  
Aldehyde Dehydrogenase 2 ◽  
Cross Sectional ◽  
Asian Populations ◽  
Aldehyde Dehydrogenase 2 Gene

Background:The association of genetic polymorphism of mitochondrial aldehyde dehydrogenase 2 (ALDH2) and Alzheimer's disease (AD) has been controversial and has been investigated only in several small-sample studies. In the present study, we performed a meta-analysis to evaluate the cross-sectional association ofALDH2variants and AD risk in East Asian populations.Methods:Trials were retrieved through MEDLINE, EMBASE, J-STAGE and the China National Knowledge Internet databases (from January 1, 1994 to November 1, 2010) without any restriction on language. Data were abstracted by a standardized protocol.Results:We found four studies of 821AD patients and 1380 healthy controls that qualified for the analysis. The variantALDH2genotype GA/AA was not associated with increased AD risk (odds ratio (OR) = 1.35; 95% confidence interval (CI) = 0.75-2.42; p = 0.32), even after stratification for the status of apolipoprotein E epsilon 4 allele. However, in the subgroup analyses, the association was significant for men (OR = 1.72; 95% CI = 1.10-2.67; p = 0.02).Conclusions:This study adds to the evidence thatALDH2GA/AA genotype increases the risk of AD among East Asian men, although the effect size is moderate.

scholarly journals Effect of Aldehyde Dehydrogenase 2 Gene Polymorphism on Executive Function in Opiate User

2018 ◽  
Vol 08 (03) ◽  
Author(s):  
Po Chih Liu ◽  
Po See Chen ◽  
Ru Band Lu ◽  
Chun Hsiang Tan ◽  
Shao Ching Tu ◽  
...  
Keyword(s):  
Executive Function ◽  
Gene Polymorphism ◽  
Aldehyde Dehydrogenase ◽  
Aldehyde Dehydrogenase 2 ◽  
Opiate User ◽  
Aldehyde Dehydrogenase 2 Gene
Sign in / Sign up

Export Citation Format

Share Document