Decreased spatial frequency sensitivities for processing faces in male patients with chronic schizophrenia

In a sample of 120 long-stay in-patients who fulfilled DSM–III–R criteria for schizophrenia, chronic akathisia and pseudoakathisia were relatively common, with prevalence figures of 24% and 18%, respectively. Compared with patients without evidence of chronic akathisia, those patients with the condition were significantly younger, were receiving significantly higher doses of antipsychotic medication, and were more likely to be receiving a depot antipsychotic. Patients who experienced the characteristic inner restlessness and compulsion to move of akathisia also reported marked symptoms of dysphoria, namely tension, panic, irritability and impatience. The findings support the suggestion that dysphoric mood is an important feature of akathisia. Male patients appeared to be at an increased risk of pseudoakathisia. No significant relation was found between chronic akathisia and tardive dyskinesia, although there was a trend for trunk and limb dyskinesia to be commonest in patients with chronic akathisia while orofacial dyskinesia was most frequently observed in those with pseudoakathisia. Akathisia may mask the movements of tardive dyskinesia in the lower limb. There was no evidence that akathisia was associated with positive or negative symptoms of schizophrenia nor with depression.

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mGluR5 receptor availability is associated with lower levels of negative symptoms and better cognition in male patients with chronic schizophrenia

Human Brain Mapping ◽

10.1002/hbm.24976 ◽

2020 ◽

Vol 41 (10) ◽

pp. 2762-2781 ◽

Cited By ~ 2

Author(s):

Cláudia Régio Brambilla ◽

Tanja Veselinović ◽

Ravichandran Rajkumar ◽

Jörg Mauler ◽

Linda Orth ◽

...

Keyword(s):

Negative Symptoms ◽

Chronic Schizophrenia ◽

Male Patients

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Association of cigarette smoking with cognitive impairment in male patients with chronic schizophrenia

Psychopharmacology ◽

10.1007/s00213-020-05621-w ◽

2020 ◽

Vol 237 (11) ◽

pp. 3409-3416

Author(s):

Shuochi Wei ◽

Dongmei Wang ◽

Gaoxia Wei ◽

Jiesi Wang ◽

Huixia Zhou ◽

...

Keyword(s):

Cognitive Impairment ◽

Cigarette Smoking ◽

Chronic Schizophrenia ◽

Male Patients

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Experience with Thioridazine (“Melleril”) Therapy

Journal of Mental Science ◽

10.1192/bjp.107.448.523 ◽

1961 ◽

Vol 107 (448) ◽

pp. 523-528 ◽

Cited By ~ 4

Author(s):

N. Gold

Keyword(s):

Side Effects ◽

Pilot Trial ◽

Chronic Schizophrenia ◽

Phenothiazine Derivatives ◽

Male Patients ◽

Closed Ward

“A doctor must know not only the virtue of a drug, but also its drawbacks”—Carling (1960).Thioridazine is one of the newer phenothiazine derivatives used in psychiatry. Previous workers have reported few serious side-effects with it. The following pilot trial was carried out on male patients suffering from chronic schizophrenia who required nursing in a closed ward.

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The study of acoustic startle reflex in male patients with chronic schizophrenia

Asian Journal of Psychiatry ◽

10.1016/j.ajp.2011.12.010 ◽

2012 ◽

Vol 5 (1) ◽

pp. 54-57 ◽

Cited By ~ 1

Author(s):

Zhiren Wang ◽

Yunlong Tan ◽

Fude Yang ◽

Wufang Zhang ◽

Yizhuang Zou ◽

...

Keyword(s):

Acoustic Startle ◽

Chronic Schizophrenia ◽

Startle Reflex ◽

Acoustic Startle Reflex ◽

Male Patients

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Tardive Dyskinesia and Type II Schizophrenia

The British Journal of Psychiatry ◽

10.1192/bjp.160.2.253 ◽

1992 ◽

Vol 160 (2) ◽

pp. 253-256 ◽

Cited By ~ 18

Author(s):

Elizabeth J. B. Davis ◽

Milind Borde ◽

L. N. Sharma

Keyword(s):

Cognitive Impairment ◽

Negative Symptoms ◽

Chronic Schizophrenia ◽

Thought Disorder ◽

Control Group ◽

Positive Symptoms ◽

Type Ii ◽

Formal Thought Disorder ◽

Schizophrenic Patients ◽

Male Patients

Cognitive impairment, negative and positive symptoms, primitive release reflexes, and age/temporal disorientation were assessed in 20 male patients meeting the DSM–III–R criteria for chronic schizophrenia and Schooler & Kane's criteria for TD. The control group comprised 20 age-matched male chronic schizophrenic patients without TD. Significant associations were found between TD, cognitive impairment, some negative symptoms, and formal thought disorder. These associations were independent of other illness and treatment variables. The severity of TD correlated significantly with that of cognitive impairment.

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Brain-Derived Neurotropic Factor Serum Level and Severity Symptom of Bataknese Male Patients with Schizophrenia in North Sumatera, Indonesia

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.550 ◽

2019 ◽

Vol 7 (12) ◽

pp. 1957-1961

Author(s):

Deasy Hendriati ◽

Elemeida Effendy ◽

Mustafa Mahfud Amin ◽

Vita Camellia ◽

Muhammad Surya Husada

Keyword(s):

Serum Level ◽

Negative Correlation ◽

Symptom Severity ◽

Negative Symptoms ◽

Chronic Schizophrenia ◽

Serum Levels ◽

Cross Sectional ◽

Syndrome Scale ◽

Male Patients ◽

Negative Syndrome

BACKGROUND: Schizophrenia is a severe mental disorder that is multi-causative and multi-factor, generally affecting about 1% of the population. The elevation level of brain-derived neurotrophic factor (BDNF) offers several protections from other neurodegenerative processes that occur in schizophrenia since this deficit of neurotrophic factors can contribute to changes in brain structure and function that underlie the schizophrenia psychopathology.AIM: To analyse the correlation between BDNF serum levels and symptom severity by using the Positive and Negative Syndrome Scale (PANSS) instrument in Bataknese male patients with schizophreniaMETHODS: This study was a correlative analytical study with a cross-sectional approach using the Positive and Negative Syndrome Scale (PANSS) instrument to assess symptom severity with 60 subjects of Bataknese male patients with chronic schizophrenia. Moreover, this research was conducted at the Psychiatric Hospital of Prof. Dr M. Ildrem Medan, Indonesia. BDNF serum was analysed with the Quantitative sandwich enzyme immunoassay technique by via Quantikine ELISA Human CXCL8/IL-8 HS. Also, the data analysis was performed through Spearman's correlative bivariate analytics using SPSS software.RESULTS: A negative correlation between the BDNF serum level and the negative scale PANSS score in men with schizophrenia (r = -0.820, p < 0.001) was found. Moreover, there is a negative correlation between BDNF serum levels and PANSS total scores in men with schizophrenia (r = -0.648, p < 0.001)CONCLUSION: BDNF serum level in Bataknese male patients with schizophrenia has a relationship that affects the severity of symptoms in schizophrenic patients, especially for negative symptoms.

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