MRI of soft-tissue masses: the relationship between lesion size, depth, and diagnosis

2008 ◽  
Vol 63 (4) ◽  
pp. 379-380
Author(s):  
C.J. Wakeley
Keyword(s):  
Soft Tissue ◽  
Lesion Size ◽  
Soft Tissue Masses ◽  
The Relationship

MRI of soft-tissue masses: the relationship between lesion size, depth, and diagnosis

2008 ◽  
Vol 63 (4) ◽  
pp. 373-378 ◽  
Author(s):  
A. Datir ◽  
S.L.J. James ◽  
K. Ali ◽  
J. Lee ◽  
M. Ahmad ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Lesion Size ◽  
Soft Tissue Masses ◽  
The Relationship

scholarly journals Assessment of Referrals into the Soft Tissue Sarcoma Service: Evaluation of Imaging Early in the Pathway Process

Sarcoma ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Emma Rowbotham ◽  
Shaheel Bhuva ◽  
Harun Gupta ◽  
Philip Robinson
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Service Evaluation ◽  
Lesion Size ◽  
Imaging Diagnosis ◽  
Local Hospital ◽  
Patient Demographics ◽  
Tertiary Centre ◽  
Soft Tissue Masses ◽  
Malignant Lesions

Purpose. To prospectively evaluate regional referrals into a soft tissue sarcoma service from outside the tertiary centre with local hospital imaging.Materials and Methods. Consecutive referrals were prospectively assessed for: patient demographics, source, referral date, date received by Multidisciplinary Team (MDT), lesion size, local radiology, MDT radiology and final diagnoses. Radiology diagnosis was categorised benign, indeterminate or malignant by consensus. Delays were defined as >10 days.Results. 112 patients were included with high correlation between local and MDT radiology categrorisation and histology (P=0.54andP=0.49, resp.). There was only a trend for MDT radiology diagnosis to downgrade local imaging diagnosis (n=15,P>0.05). 48 cases (43%) had ultrasound and MRI at referral and 20 (18%) ultrasound only. 85% of cases were benign (lipoma most common), 15% malignant (sarcoma most common). Delay occurred in 34% of cases.Discussion. In comparison to previous series these results show a reduction in benign lesions, increased biopsy and malignancy rate for lesions referred to a tertiary centre when imaging is performed and reviewed by local radiologists.Advances in Knowledge. Imaging triage of soft tissue masses can decrease benign referral rates and increase the proportion of indeterminate and malignant lesions referred to specialist centres.

Benign Soft Tissue Masses

2019 ◽  
pp. 337-345
Author(s):  
Kevin J. Blount
Keyword(s):  
Soft Tissue ◽  
Clinical Presentation ◽  
Comprehensive Evaluation ◽  
Definitive Diagnosis ◽  
Imaging Appearance ◽  
Soft Tissue Masses ◽  
Malignant Lesions ◽  
Relationship Of ◽  
The Relationship ◽  
Internal Architecture

Chapter 65 discusses benign soft tissue masses, which are much more common than malignant lesions; however, there can be overlap between these categories, and some lesions have features that are indeterminate. In many cases, the clinical presentation is not clearly diagnostic, and patients with soft tissue lesions require additional evaluation with imaging and biopsy. Radiography, MRI, and US serve complementary roles in the workup of soft tissue masses, with MRI providing the most comprehensive evaluation in most cases. Although imaging sometimes cannot confirm a definitive diagnosis, the imaging appearance plays an important role in the workup of soft tissue masses and tumorlike conditions. The most important features to evaluate are the internal architecture of the lesion, defining the anatomic location of the lesion, and assessing the relationship of the soft tissue lesion to surrounding vital structures.

scholarly journals The safety of primary surgical excision of small deep indeterminate musculoskeletal soft tissue masses

2021 ◽  
Vol 94 (1117) ◽  
pp. 20200713
Author(s):  
Michèle Calleja ◽  
Qasim Afzaal ◽  
Asif Saifuddin
Keyword(s):  
Soft Tissue ◽  
Residual Disease ◽  
Surgical Excision ◽  
Lesion Size ◽  
Safe Procedure ◽  
Deep Soft Tissue ◽  
Tissue Mass ◽  
Oncology Service ◽  
Soft Tissue Masses ◽  
Musculoskeletal Oncology

Objective: To determine the suitability of primary excision of small indeterminate deep soft tissue masses presenting to a tertiary musculoskeletal oncology service. Methods and materials: Review of all patients referred to a specialist musculoskeletal oncology service over a 20-month period with a deep indeterminate soft tissue mass by non-contrast MRI criteria that was recommended for primary surgical excision due to relatively small size (<30 mm). Data collected included age, gender, site and maximal size of the lesion, and final histological diagnosis for excised lesions. Results: 85 patients were included, mean lesion size being 12 mm (range 5–29 mm). Primary surgical resection had been undertaken in 69 cases (81.2%) by the conclusion of data collection, 36 males and 33 females with mean age of 45.6 years (range 11–80 years). Of these, 11 cases (15.9%) were non-neoplastic, 53 (76.8%) were benign, 1 (1.4%) was intermediate grade, while 4 (5.8%) were malignant including 3 synovial sarcomas. Two of these were treated with re-excision of the tumour bed showing no residual disease, with no evidence of local recurrence at a mean of 10.7 months post-excision. Conclusion: Primary surgical excision of small deep soft tissue masses that are indeterminate by non-contrast MRI criteria is considered a safe procedure when undertaken in a specialist musculoskeletal oncology service, with only 4 of 69 cases (5.8%) being malignant. Advances in knowledge: Small indeterminate deep soft tissue masses can safely be treated with primary excision in the setting of a specialist musculoskeletal oncology service.

scholarly journals Nasal Morphology and Its Correlation to Craniofacial Morphology in Lateral Cephalometric Analysis

2021 ◽  
Vol 18 (6) ◽  
pp. 3064
Author(s):  
Agnieszka Jankowska ◽  
Joanna Janiszewska-Olszowska ◽  
Katarzyna Grocholewicz
Keyword(s):  
Soft Tissue ◽  
Nasal Bone ◽  
Correlation Coefficients ◽  
Craniofacial Morphology ◽  
Base Angle ◽  
Nasolabial Angle ◽  
Orthodontic Patients ◽  
Nose Shape ◽  
The Relationship ◽  
Spearman’S Correlation

Nose shape, size, and inclination influence facial appearance, but few studies concern the relationship between the nasal profile and craniofacial structures. The objective of this study was to analyze association of nasal cephalometric variables with skeletal structures, age, and sex. Cephalometric and nasal analysis was performed in 386 Polish orthodontic patients (aged 9–25 years). Student t-test and Mann–Whitney test were used to compare quantitative variables and Pearson’s or Spearman’s correlation coefficients—to find correlations. Soft tissue facial convexity angle correlates to Holdaway ratio, ANB (A-Nasion-B), and Wits appraisal. Nasal dorsum axis, nose length, nose depth (1) and nose depth (2), nose hump, lower dorsum convexity, and columella convexity increase with age. Nasal base angle, nasolabial angle, nasomental angle, soft tissue facial convexity and nasal bone angle decrease with age. Nasal base angle and nasomental angle are smaller in females. Thus, a relationship exists between nasal morphology and sagittal jaw configuration. Nasal parameters significantly change with age. Sexual dimorphism characterizes nasal bone angle and nasomental angle.

scholarly journals Soft tissue masses: distribution of entities and rate of malignancy in small lesions

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Felix G. Gassert ◽  
Florian T. Gassert ◽  
Katja Specht ◽  
Carolin Knebel ◽  
Ulrich Lenze ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Benign Lesion ◽  
Maximum Diameter ◽  
Histopathological Diagnosis ◽  
Tumor Diameter ◽  
Mr Images ◽  
Tissue Mass ◽  
Malignancy Rate ◽  
Significant Difference ◽  
Soft Tissue Masses

Abstract Background Small soft tissue masses are often falsely assumed to be benign and resected with failure to achieve tumor-free margins. Therefore, this study retrospectively investigated the distribution of histopathologic diagnosis to be encountered in small soft tissue tumors (≤ 5 cm) in a large series of a tertiary referral center. Methods Patients with a soft tissue mass (STM) with a maximum diameter of 5 cm presenting at our institution over a period of 10 years, who had undergone preoperative Magnetic resonance imaging and consequent biopsy or/and surgical resection, were included in this study. A final histopathological diagnosis was available in all cases. The maximum tumor diameter was determined on MR images by one radiologist. Moreover, tumor localization (head/neck, trunk, upper extremity, lower extremity, hand, foot) and depth (superficial / deep to fascia) were assessed. Results In total, histopathologic results and MR images of 1753 patients were reviewed. Eight hundred seventy patients (49.63%) showed a STM ≤ 5 cm and were therefore included in this study (46.79 +/− 18.08 years, 464 women). Mean maximum diameter of the assessed STMs was 2.88 cm. Of 870 analyzed lesions ≤ 5 cm, 170 (19.54%) were classified as superficial and 700 (80.46%) as deep. The malignancy rate of all lesions ≤ 5 cm was at 22.41% (superficial: 23.53% / deep: 22.14%). The malignancy rate dropped to 16.49% (20.79% / 15.32%) when assessing lesions ≤ 3 cm (p = 0.007) and to 15.0% (18.18% / 13.79%) when assessing lesions ≤ 2 cm (p = 0.006). Overall, lipoma was the most common benign lesion of superficial STMs (29.41%) and tenosynovial giant cell tumor was the most common benign lesion of deep STMs (23.29%). Undifferentiated pleomorphic sarcoma was the most common malignant diagnosis among both, superficial (5.29%) and deep (3.57%) STMs. Conclusions The rate of malignancy decreased significantly with tumor size in both, superficial and deep STMs. The distribution of entities was different between superficial and deep STMs, yet there was no significant difference found in the malignancy rate.

Predicting in Vivo Soft Tissue Masses of the Lower Extremity Using Segment Anthropometric Measures and DXA

2005 ◽  
Vol 21 (4) ◽  
pp. 371-382 ◽  
Author(s):  
Jeffrey D. Holmes ◽  
David M. Andrews ◽  
Jennifer L. Durkin ◽  
James J. Dowling
Keyword(s):  
Soft Tissue ◽  
Lower Extremity ◽  
Prediction Equation ◽  
Regression Equations ◽  
Anthropometric Measures ◽  
Soft Tissue Masses ◽  
Highly Correlated ◽  
Relative Errors ◽  
Dxa Scans

The purpose of this study was to derive and validate regression equations for the prediction of fat mass (FM), lean mass (LM), wobbling mass (WM), and bone mineral content (BMC) of the thigh, leg, and leg + foot segments of living people from easily measured segmental anthropometric measures. The segment masses of 68 university-age participants (26 M, 42 F) were obtained from full-body dual photon x-ray absorptiometry (DXA) scans, and were used as the criterion values against which predicted masses were compared. Comprehensive anthropometric measures (6 lengths, 6 circumferences, 8 breadths, 4 skinfolds) were taken bilaterally for the thigh and leg for each person. Stepwise multiple linear regression was used to derive a prediction equation for each mass type and segment. Prediction equations exhibited high adjustedR2values in general (0.673 to 0.925), with higher correlations evident for the LM and WM equations than for FM and BMC. Predicted (equations) and measured (DXA) segment LM and WM were also found to be highly correlated (R2= 0.85 to 0.96), and FM and BMC to a lesser extent (R2= 0.49 to 0.78). Relative errors between predicted and measured masses ranged between 0.7% and –11.3% for all those in the validation sample (n= 16). These results on university-age men and women are encouraging and suggest that in vivo estimates of the soft tissue masses of the lower extremity can be made fairly accurately from simple segmental anthropometric measures.

Chalastospora gossypii in a Maine Coon cat: case report and literature review

2021 ◽  
pp. 104063872110222
Author(s):  
Samantha M. Norris ◽  
Paula A. Schaffer ◽  
Noah B. Bander
Keyword(s):  
Soft Tissue ◽  
Needle Aspiration ◽  
Tissue Mass ◽  
Large Numbers ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Soft Tissue Masses ◽  
Subcutaneous Mass ◽  
The Right ◽  
A Minor

A 15-y-old castrated male Maine Coon cat was evaluated for an ulcerated soft tissue mass on the right hindlimb that had been observed for 4 mo and had grown rapidly. A 3 × 3 cm soft, raised, amorphous, and ulcerated subcutaneous mass was observed on the lateral right metatarsus. In-house cytology via fine-needle aspiration was nondiagnostic. Incisional biopsy of the mass and further staging was declined, and amputation was elected. The amputated limb was submitted for histopathology, which revealed severe chronic nodular granulomatous dermatitis and multifocal granulomatous popliteal lymphadenitis with large numbers of intralesional fungal hyphae. Fungal PCR and sequencing on formalin-fixed, paraffin-embedded tissue identified Chalastospora gossypii. No adjunctive therapy was elected at the time. The patient has done well clinically 1 y post-operatively. C. gossypii is a rare microfungus found worldwide and is considered a minor pathogen of several plants. To our knowledge, infection by this fungus has not been reported previously in veterinary species. Features in our case are comparable to other mycotic infections. Nodular granulomatous mycotic dermatitis and cellulitis, although uncommon, should be a differential for soft tissue masses in veterinary species; C. gossypii is a novel isolate.

Neonatal vascular anomalies manifesting as soft-tissue masses

2021 ◽  
Author(s):  
Nadeen Abu Ata ◽  
Adrienne M. Hammill ◽  
Arnold C. Merrow
Keyword(s):  
Soft Tissue ◽  
Vascular Anomalies ◽  
Soft Tissue Masses
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