scholarly journals No evidence of association between habitual physical activity and ECG traits Insights from the electronic Framingham Heart Study

2021 ◽  
Author(s):  
Jelena Kornej ◽  
Joanne M. Murabito ◽  
Yuankai Zhang ◽  
Chunyu Liu ◽  
Ludovic Trinquart ◽  
...  
Keyword(s):  
Physical Activity ◽  
Framingham Heart Study ◽  
Habitual Physical Activity ◽  
Heart Study

ASSOCIATION OF HABITUAL PHYSICAL ACTIVITY WITH HOME BLOOD PRESSURE: INSIGHTS FROM THE ELECTRONIC FRAMINGHAM HEART STUDY

2020 ◽  
Vol 75 (11) ◽  
pp. 16
Author(s):  
Mayank Sardana ◽  
Honghuang Lin ◽  
Ludovic Trinquart ◽  
Yuankai Zhang ◽  
Chunyu Liu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Framingham Heart Study ◽  
Home Blood Pressure ◽  
Habitual Physical Activity ◽  
Heart Study

scholarly journals Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study

10.2196/25591 ◽  
2021 ◽  
Vol 23 (6) ◽  
pp. e25591
Author(s):  
Mayank Sardana ◽  
Honghuang Lin ◽  
Yuankai Zhang ◽  
Chunyu Liu ◽  
Ludovic Trinquart ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Habitual Physical Activity ◽  
Step Count ◽  
Daily Step ◽  
Community Based ◽  
Cross Sectional ◽  
Heart Study ◽  
Daily Step Count ◽  
The Mean

Background When studied in community-based samples, the association of physical activity with blood pressure (BP) remains controversial and is perhaps dependent on the intensity of physical activity. Prior studies have not explored the association of smartwatch-measured physical activity with home BP. Objective We aimed to study the association of habitual physical activity with home BP. Methods Consenting electronic Framingham Heart Study (eFHS) participants were provided with a study smartwatch (Apple Watch Series 0) and Bluetooth-enabled home BP cuff. Participants were instructed to wear the watch daily and transmit BP values weekly. We measured habitual physical activity as the average daily step count determined by the smartwatch. We estimated the cross-sectional association between physical activity and average home BP using linear mixed effects models adjusting for age, sex, wear time, antihypertensive drug use, and familial structure. Results We studied 660 eFHS participants (mean age 53 years, SD 9 years; 387 [58.6%] women; 602 [91.2%] White) who wore the smartwatch 5 or more hours per day for 30 or more days and transmitted three or more BP readings. The mean daily step count was 7595 (SD 2718). The mean home systolic and diastolic BP (mmHg) were 122 (SD 12) and 76 (SD 8). Every 1000 increase in the step count was associated with a 0.49 mmHg lower home systolic BP (P=.004) and 0.36 mmHg lower home diastolic BP (P=.003). The association, however, was attenuated and became statistically nonsignificant with further adjustment for BMI. Conclusions In this community-based sample of adults, higher daily habitual physical activity measured by a smartwatch was associated with a moderate, but statistically significant, reduction in home BP. Differences in BMI among study participants accounted for the majority of the observed association.

scholarly journals The conjoint associations of adherence to physical activity and dietary guidelines with cardiometabolic health: The Framingham Heart Study

2020 ◽  
Author(s):  
Joowon Lee ◽  
Maura E. Walker ◽  
Maximillian T. Bourdillon ◽  
Nicole Spartano ◽  
Gail T. Rogers ◽  
...  
Keyword(s):  
Physical Activity ◽  
Framingham Heart Study ◽  
Lower Risk ◽  
Later Life ◽  
Cox Proportional Hazards ◽  
Dietary Guidelines ◽  
Cardiometabolic Health ◽  
The Metabolic Syndrome ◽  
Heart Study ◽  
Referent Group

Abstract Background The conjoint associations of adherence to the recent physical activity (PA) and dietary guidelines with the metabolic syndrome (MetS) are incompletely understood. Methods We evaluated 2,379 Framingham Heart Study Third Generation participants (mean age 47 years, 54.4% women) attending examination cycle 2. We examined the cross-sectional relations of adherence to the 2018 Physical Activity Guidelines for Americans (PAG, binary; moderate to vigorous PA [MVPA] ≥ 150 minutes/week vs. <150 minutes/week) and 2015 Dietary Guidelines for Americans (DGA, binary; 2015 DGA adherence Index [DGAI-2015] ≥ median vs. <median [score 62.1/100]) with prevalence of the MetS using generalized linear models. We also related adherence to guidelines with the incidence of MetS prospectively, using Cox proportional hazards regression with discrete time intervals. Results Adherence to the 2018 PAG (odds ratio [OR] 0.49, 95% CI 0.40–0.60) and 2015 DGA (OR 0.67, 95% CI 0.51–0.90) were individually associated with lower odds of prevalent MetS, while conjoint adherence to both guidelines was associated with the lowest odds of MetS (OR 0.35, 95% CI 0.26–0.47) compared to the referent group (non-adherence to both guidelines). Adherence to the 2018 PAG (hazards ratio [HR] 0.66, 95% CI 0.50–0.88) and 2015 DGA (HR 0.68, 95% CI 0.51–0.90) were associated with lower risk of MetS, prospectively. Additionally, we observed a 52% lower risk of MetS in individuals who adhered to both guidelines compared to the referent group. Conclusions Maintaining both regular physical activity and a healthy diet in midlife may be required for optimal cardiometabolic health in later life.

scholarly journals Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study

2013 ◽  
Vol 15 (7) ◽  
pp. 742-746 ◽  
Author(s):  
Elisabeth Kraigher-Krainer ◽  
Asya Lyass ◽  
Joseph M. Massaro ◽  
Douglas S. Lee ◽  
Jennifer E. Ho ◽  
...  
Keyword(s):  
Physical Activity ◽  
Heart Failure ◽  
Ejection Fraction ◽  
Framingham Heart Study ◽  
The Elderly ◽  
Reduced Ejection Fraction ◽  
Heart Study

scholarly journals Physical Activity and Life Expectancy With and Without Diabetes: Life table analysis of the Framingham Heart Study

Diabetes Care ◽  
2005 ◽  
Vol 29 (1) ◽  
pp. 38-43 ◽  
Author(s):  
J. T. Jonker ◽  
C. De Laet ◽  
O. H. Franco ◽  
A. Peeters ◽  
J. Mackenbach ◽  
...  
Keyword(s):  
Physical Activity ◽  
Life Expectancy ◽  
Life Table ◽  
Framingham Heart Study ◽  
Life Table Analysis ◽  
Heart Study ◽  
Table Analysis

Physical activity and mortality in women in the Framingham Heart Study

1994 ◽  
Vol 128 (5) ◽  
pp. 879-884 ◽  
Author(s):  
Scott E. Sherman ◽  
Ralph B. D'Agostino ◽  
Janet L. Cobb ◽  
William B. Kannel
Keyword(s):  
Physical Activity ◽  
Framingham Heart Study ◽  
Heart Study

Abstract MP059: Incremental Light Activity Associated with Greater Brain Volume in Individuals Not Meeting the Physical Activity Guidelines: Cross Sectional Observations from the Framingham Heart Study

Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Nicole L Spartano ◽  
Kendra L Davis-Plourde ◽  
Jayandra J Himali ◽  
Ludovic Trinquart ◽  
Charlotte Andersson ◽  
...  
Keyword(s):  
Physical Activity ◽  
Framingham Heart Study ◽  
Sedentary Time ◽  
Brain Volume ◽  
Brain Aging ◽  
Time Of Day ◽  
Physical Activity Guidelines ◽  
Wear Time ◽  
Heart Study ◽  
Light Activity

Background: Recent evidence suggests that dementia appears linked to subclinical vascular changes, which may be attenuated by physical activity. The Physical Activity Guidelines for Americans (PA-Guidelines) are currently set at 150 min of moderate-to-vigorous physical activity (MVPA) per week, as a target for adults to achieve favorable health outcomes, but make no specific recommendations for prevention of dementia. Many Americans fall well below the PA-Guidelines. The aim of this investigation was to determine whether there is a continuum of lower intensities and volumes of physical activity associated with healthy brain aging even in individuals not meeting the PA-Guidelines. Methods: We included Framingham Heart Study (FHS) participants who wore an Actical accelerometer for ≥3 valid days (>10 h wear time per day) on their right hip during the most recent cohort examinations and completed brain magnetic resonance imaging (MRI) an average of 1.7 (±0.9) years later (n=2534): Offspring exam 9, Third Generation exam 2, and corresponding examinations of the Omni cohorts. Participants were excluded from this analysis if they had prevalent stroke or dementia (n=63) or met the 150 min MVPA per week PA-Guidelines (n=1158). Non-wear time (defined as 60 min of zero-counts, with two interruptions allowed) was removed. Sedentary time (<200 counts/min, <1.5 metabolic equivalents [METs]) and light activity (201-1485 counts/min, 1.5-3 METs) were only accumulated during 6 am-10 pm, were represented as proportions of wear time to account for differences in wear time among participants, and standardized to a 16 h day. MVPA (>1486 counts/min, ≥3 METs) and steps were accumulated at any time of day. The relations of physical activity measures to brain MRI measures were assessed using multivariable linear regression. Results: More than 53% of FHS participants did not meet the PA-Guidelines for MVPA during their last exam, and were thus included in this investigation (n=1313, 56 [±14] years old, 60% women). These participants took an average of 6149 [±3079] steps, spent 10.5 [±6.1] min MVPA, 13 h 36 min [±48 min] sedentary and 2 h 14 min [±48 min] in light activities per day. Each additional 40 min of light activity (spent in 1.5-3 METs) or 42 min less time spent sedentary was associated with 0.22% [±0.07%] greater total cerebral brain volume (TCBV), after adjusting for age, sex, body mass index, smoking, diabetes mellitus, and cardiovascular disease (p=0.001), equivalent to approximately 1.1 years less brain aging. Greater light activity and lower sedentary time were also associated with greater hippocampal volume (p<0.005). Conclusions: Our investigation demonstrates, in a community setting, that there may be a negative association of light physical activity with brain aging even among individuals not meeting the PA-Guidelines for MVPA.

Physical Activity and Risk of Breast Cancer in the Framingham Heart Study

1994 ◽  
Vol 139 (7) ◽  
pp. 662-669 ◽  
Author(s):  
Joanne F. Dorgan ◽  
Charles Brown ◽  
Michael Barrett ◽  
Greta L. Splansky ◽  
Bemard E. Kreger ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Framingham Heart Study ◽  
Heart Study

scholarly journals Association of Habitual Physical Activity With Cardiovascular Disease Risk

2020 ◽  
Vol 127 (10) ◽  
pp. 1253-1260
Author(s):  
Honghuang Lin ◽  
Mayank Sardana ◽  
Yuankai Zhang ◽  
Chunyu Liu ◽  
Ludovic Trinquart ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Daily Activity ◽  
Interquartile Range ◽  
Habitual Physical Activity ◽  
Daily Step ◽  
Cvd Risk ◽  
Heart Study ◽  
Daily Step Count ◽  
Predicted Risk

Rationale: A sedentary lifestyle is associated with increased risk for cardiovascular disease (CVD). Smartwatches enable accurate daily activity monitoring for physical activity measurement and intervention. Few studies, however, have examined physical activity measures from smartwatches in relation to traditional risk factors associated with future risk for CVD. Objective: To investigate the association of habitual physical activity measured by smartwatch with predicted CVD risk in adults. Methods and Results: We enrolled consenting FHS (Framingham Heart Study) participants in an ongoing eFHS (electronic Framingham Heart Study) at the time of their FHS research center examination. We provided participants with a smartwatch (Apple Watch Series 0) and instructed them to wear it daily, which measured their habitual physical activity as the average daily step count. We estimated the 10-year predicted risk of CVD using the American College of Cardiology/American Heart Association 2013 pooled cohort risk equation. We estimated the association between physical activity and predicted risk of CVD using linear mixed effects models adjusting for age, sex, wear time, and familial structure. Our study included 903 eFHS participants (mean age 53±9 years, 61% women, 9% non-White) who wore the smartwatch ≥5 hours per day for ≥30 days. Median daily step count was similar among men (7202 with interquartile range 3619) and women (7260 with interquartile range 3068; P =0.52). Average 10-year predicted CVD risk was 4.5% (interquartile range, 6.1%) for men and 1.2% (interquartile range, 2.2%) for women ( P =1.3×10 −26 ). Every 1000 steps higher habitual physical activity was associated with 0.18% lower predicted CVD risk ( P =3.2×10 −4 ). The association was attenuated but remained significant after further adjustment for body mass index ( P =0.01). Conclusions: In this community-based sample of adults, higher daily physical activity measured by a study smartwatch was associated with lower predicted risk of CVD. Future research should examine the longitudinal association of prospectively measured daily activity and incident CVD.

924 Non-Alcoholic Fatty Liver Disease Is Associated With Lower Levels of Physical Activity Measured via Accelerometry: The Framingham Heart Study

2014 ◽  
Vol 146 (5) ◽  
pp. S-929 ◽  
Author(s):  
Michelle Long ◽  
Alison Pedley ◽  
Joseph M. Massaro ◽  
Udo Hoffmann ◽  
Ramachandran S. Vasan ◽  
...  
Keyword(s):  
Physical Activity ◽  
Liver Disease ◽  
Fatty Liver ◽  
Framingham Heart Study ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Heart Study ◽  
Alcoholic Fatty Liver Disease
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