Heart rate variability predicts alcohol craving in alcohol dependent outpatients: Further evidence for HRV as a psychophysiological marker of self-regulation

2013 ◽  
Vol 132 (1-2) ◽  
pp. 395-398 ◽  
Author(s):  
Daniel S. Quintana ◽  
Adam J. Guastella ◽  
Iain S. McGregor ◽  
Ian B. Hickie ◽  
Andrew H. Kemp
2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Ana Isabel Penzlin ◽  
Kristian Barlinn ◽  
Ben Min-Woo Illigens ◽  
Kerstin Weidner ◽  
Martin Siepmann ◽  
...  

2013 ◽  
Vol 55 (2) ◽  
pp. 173 ◽  
Author(s):  
Kesavan Muralidharan ◽  
Vivek Benegal ◽  
BangaloreN Gangadhar ◽  
Suhas Ganesha ◽  
Jagadisha Thirthalli

2020 ◽  
Vol 19 ◽  
pp. 153473542094967
Author(s):  
Linda Larkey ◽  
Wonsun Kim ◽  
Dara James ◽  
Moé Kishida ◽  
Maricarmen Vizcaino ◽  
...  

Background: Advancements in early detection and treatment of cancer have led to increased survival rates and greater need to identify effective supportive care options for resolving symptoms of survivorship. Many non-pharmacological approaches to symptom management during and after cancer treatment involve emotional self-regulation as a central strategy for improving well-being. Identifying commonalities among these strategies’ mechanisms of action may facilitate understanding of what might be useful for optimizing intervention effects. Heart rate variability (HRV) parameters are indicative of improved autonomic nervous system (ANS) balance and resiliency and reduced emotional distress and are thus identified as a mechanism to discuss as a marker of potential for intervention efficacy and a target for optimization. Methods: HRV data from 2 studies, 1 examining a mind-body intervention and 1 examining a psychosocial intervention, are presented as a point of discussion about preliminary associations between the interventions, change in HRV, and emotional distress reduction. Results: HRV significantly decreased in sympathetic activity in response to a mind-body intervention (Qigong/Tai Chi), and increased vagal tone in response to a psychosocial (storytelling) intervention. In both, these changes in HRV parameters were associated with improved emotional states. Conclusion: Our preliminary data suggest that HRV may serve as an important marker of underlying changes that mediate emotional regulation; this observation deserves further investigation. If identified as a worthy target, focusing on interventions that improve HRV within the context of interventions for cancer patients may be important to key outcomes and clinical practice.


2020 ◽  
Author(s):  
Sihong Liu ◽  
Assaf Oshri ◽  
Erinn Duprey

Background and Objectives. Young adults with childhood maltreatment (CM) histories are particularly vulnerable to depressive symptoms and alcohol use problems. Research suggest that maltreated youth may misuse alcohol in part to alleviate depressive symptoms. However, many youths with depressive symptoms exercise self-control and abstain from heavy alcohol use. The present study aimed to examine the influence of heart rate variability reactivity (HRV-R), a psychophysiological biomarker of self-regulation, in the indirect link between CM and alcohol use problems via depressive symptoms among low socioeconomic-status rural young adults. Methods. Two waves of data were collected from a community sample of 225 low socioeconomic-status non-metropolitan young adults (Mage = 21.56, 52.9% female). HRV data were obtained with an electrocardiogram during a social stress task. CM was assessed through the Childhood Trauma Questionnaire. Alcohol use problems were measured using the Alcohol Use Disorders Identification Test. Results. The indirect effect of CM on alcohol use problems via elevated depressive symptoms was positive and significant (α*β = .159, p < .001). Self-regulation indicated by high HRV-R (i.e., vagal withdrawal) was found to significantly buffer the link between depressive symptoms and alcohol use problems (β = .193, p = .022). Discussion and Conclusions. Adequate self-regulation capacities can protect maltreated youths from self-medicating alcohol use problems. Scientific Significance. This study will advance researchers’ understanding of the development of alcohol use problems through unwrapping the risk and protective mechanisms underlying the association between young adults’ early life stress and alcohol use behaviors.


PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0244427
Author(s):  
Josiane Jauniaux ◽  
Marie-Hélène Tessier ◽  
Sophie Regueiro ◽  
Florian Chouchou ◽  
Alexis Fortin-Côté ◽  
...  

Although emotion regulation has been proposed to be crucial for empathy, investigations on emotion regulation have been primarily limited to intrapersonal processes, leaving the interpersonal processes of self-regulation rather unexplored. Moreover, studies showed that emotion regulation and empathy are related with increased autonomic activation. How emotion regulation and empathy are related at the autonomic level, and more specifically during differently valenced social situations remains an open question. Healthy adults viewed a series of short videos illustrating a target who was expressing positive, negative, or no emotions during a social situation (Positive, Negative, or Neutral Social Scenes). Prior to each video, participants were instructed to reappraise their own emotions (Up-regulation, Down-regulation, or No-regulation). To assess autonomic activation, RR intervals (RRI), high frequency (HF) components of heart rate variability (HRV), and electrodermal activity phasic responses (EDRs) were calculated. Situational empathy was measured through a visual analogue scale. Participants rated how empathic they felt for a specific target. Up- and Down-regulation were related to an increase and a decrease in situational empathy and an increase in RRI and HF, respectively, compared to the control condition (No-regulation). This suggests increased activity of the parasympathetic branch during emotion regulation of situational empathic responses. Positive compared to Negative Social Scenes were associated with decreased situational empathy, in addition to a slightly but non-significantly increased HF. Altogether, this study demonstrates that emotion regulation may be associated with changes in situational empathy and autonomic responses, preferentially dominated by the parasympathetic branch and possibly reflecting an increase of regulatory processes. Furthermore, the current study provides evidence that empathy for different emotional valences is associated with distinct changes in situational empathy and autonomic responses.


2015 ◽  
Vol 29 (3) ◽  
pp. 87-98 ◽  
Author(s):  
Tien-Yu Chen ◽  
Chuan-Chia Chang ◽  
Nian-Sheng Tzeng ◽  
Terry B. J. Kuo ◽  
San-Yuan Huang ◽  
...  

Abstract. The aim of the present study was to examine cardiac autonomic function during acute alcohol withdrawal (AW) in two clinical subgroups with alcohol dependence. To this end we compared 24 patients with pure alcohol dependence (Pure ALC) with 24 alcohol-dependent patients who had comorbid symptoms of anxiety and/or depression (ANX/DEP ALC) on their mean heart rate and several (spectral) measures of heart rate variability (HRV) obtained from the patients when they were withdrawn from alcohol. To elucidate the contribution of anxiety and depression to the cardiac measures we moreover compared these groups to 120 non-comorbid patients with major depressive disorder (MDD), 24 patients with anxiety disorders and 120 matched controls. The Hamilton Depression Rating Scale (HAM-D) and the Hamilton Anxiety Rating Scale (HAM-A) were employed for the clinical symptom ratings. The cardiac measures were found to significantly discriminate among the groups (Hotelling-Lawley F = 3.18, p < .001). Post hoc testing revealed that total HRV (variance in interbeat intervals) was reduced in Pure ALC (p = .033, Cohen’s d = −0.51), ANX/DEP ALC (p < .001, Cohen’s d = −1.33), MDD (p < .001, Cohen’s d = −0.66), and anxiety disorders (p = .002, Cohen’s d = −0.69), relative to controls. When these comparisons were adjusted for smoking history in pack-years, the results were unchanged. The ANX/DEP ALC patients showed significantly greater reduction in total HRV and high frequency (HF)-HRV compared with the Pure ALC patients. Both anxiety and depression moderated the influence of alcohol use and withdrawal on resting HRV. Our results suggest that compared to Pure ALC, ANX/DEP ALC presents a subtype of alcohol dependence with higher vulnerability to reduced HRV during acute AW. Implications for cardiovascular risk are discussed.


Author(s):  
P.V. Belogubov ◽  
V.I. Ruzov ◽  
K.N. Belogubova ◽  
M.V. Belyankin ◽  
Kh. Khalaf

The goal of the paper is to study the gender characteristics of the electrophysiological parameters of the heart in young and middle-aged patients with alcohol dependence. Materials and Methods. This study included 50 alcohol-dependent patients (mean age 38.5±6.3): among them 25 women (mean age 39.8±6.2) and 25 men (mean age 37.1±6.2). All the patients were treated in Ulyanovsk Regional Clinical Drug Treatment Hospital. All alcohol-dependent patients were diagnosed with abstinence syndrome after previous alcohol excess. The examination did not include patients over 50 years of age, patients with cardiovascular pathologies and cardiac arrhythmias. Results. Gender differences between examined parameters of heart electrical remodeling were characterized by predominance of men with a longer latest alcohol excess (p<0.05) and a higher level of sympathetic activation effects (p<0.05). The study did not reveal a direct relationship between the dispersion of the QT interval and the incidence of late ventricular potentials in patients with abstinence symptoms, which may indicate a different genesis of electrophysiological disorders. However, the authors revealed a direct relationship between the duration of the latest alcohol excess and the increase in the electric myocardium inhomogeneity (p<0.05), which indicates its influence on the repolarization processes. The prevalence of QRS complex fragmentation in men and its conjugation with electrical myocardial inhomogeneity (QT) show that men belong to a high risk group due to arrhythmogenic activity. Conclusion. Electrical heart remodeling in alcohol-dependent patients is characterized by multidirectional changes in the fragmented myocardial activity and QT dispersion: in men there prevails a slowdown in fragmented activity on the background of a decrease in the total power of the heart rate variability spectrum due to lower values of the humoral-metabolic and parasympathetic components; in women there dominate repolarization processes, which correlate with low values of humoral-metabolic and sympathetic influences on the heart rhythm. The intensity of abnormalities in the processes of ventricular myocardial repolarization in men is associated with the duration of alcohol excess, prior to hospitalization. Keywords: electrophysiological heart parameters, heart rate variability, QT interval variance, late ventricular potentials. Цель – изучить гендерные особенности электрофизиологических параметров сердца у пациентов молодого и среднего возраста с алкогольной зависимостью. Материалы и методы. В данное исследование было включено 50 чел. (средний возраст – 38,5±6,3 года): 25 женщин (средний возраст – 39,8±6,2 года) и 25 мужчин (средний возраст – 37,1±6,2 года), употребляющих алкоголь, поступивших в Ульяновскую областную клиническую наркологическую больницу на стационарное лечение. У всех алкогользависимых пациентов на момент обследования был диагностирован абстинентный синдром после перенесенного алкогольного эксцесса. В обследование не включали пациентов старше 50 лет, пациентов с наличием сердечно-сосудистой патологии и нарушениями ритма сердца. Результаты. Гендерные различия между изучаемыми параметрами электрического ремоделирования сердца характеризовались преобладанием мужчин с большей продолжительностью последнего алкогольного эксцесса (p<0,05) и более высоким уровнем симпатических активирующих влияний (p<0,05). В ходе исследования не выявлено прямой связи между дисперсией интервала QT и частотой возникновения поздних потенциалов желудочков у пациентов с абстинентным синдромом, что может указывать на различный генез возникновения электрофизиологических нарушений. Выявлена прямая связь длительности последнего алкогольного эксцесса с увеличением электрической негомогенности миокрада (p<0,05), свидетельствующая о его влиянии на процессы реполяризации. Преобладание фрагментированности комплекса QRS у мужчин и его сопряженность с электрической негомогенностью миокарда (QT) служат основанием для отнесения мужчин к группе высокого риска по аритмогенной активности. Выводы. Электрическое ремоделирование сердца у пациентов с алкогольной зависимостью характеризуется разнонаправленными изменениями фрагментированной активности миокарда и дисперсии QT: у мужчин преобладает замедление фрагментированной активности на фоне снижения суммарной мощности спектра вариабельности ритма сердца за счёт более низких значений гуморально-метаболической и парасимпатической компонент; у женщин преобладают нарушения процессов реполяризации, которые коррелируют с низкими значениями гуморально-метаболических и симпатических влияний на ритм сердца. Выраженность нарушения процессов реполяризации миокарда желудочков у мужчин ассоциирована с длительностью алкогольного эксцесса, предшествующего госпитализации. Ключевые слова: электрофизиологические параметры сердца, вариабельность ритма сердца, дисперсия интервала QT, поздние потенциалы желудочков.


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