Association of short-term exposure to ambient air pollutants with exhaled nitric oxide in hospitalized patients with respiratory-system diseases

(1) Background: Years of life lost (YLL) as a surrogate of health is important for supporting ambient air pollution related policy decisions. However, there has been little comprehensive evaluation of the short-term impact of air pollution on cause-specific YLL, especially in China. Hence in this study, we selected China as sentinel region in order to conduct a meta-analysis to evaluate disease-specific YLL due to all the main ambient air pollutants. (2) Methods: A meta-analysis was conducted to evaluate disease-specific YLL due to the main ambient air pollutants in China, and 19 studies were included. We conducted methodological quality and risk of bias assessment for each included study as well as for heterogeneity and publication bias. Subgroup analysis and sensitivity analysis were also performed. (3) Results: Meta-analysis indicated that increases in PM2.5, PM10, SO2 and NO2 were associated with 1.99–5.84 years increase in YLL from non-accidental diseases. The increase in YLL to cardiovascular disease (CVD) was associated with PM10 and NO2, and the increase in YLL to respiratory diseases (RD) was associated with PM10. (4) Conclusions: Ambient air pollution was observed to be associated with several cause-specific YLL, increasing especially for elderly people and females.

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Air pollution and hospital admissions and deaths due to respiratory infections in megacity of Tehran: A time series analysis

Journal of Air Pollution and Health ◽

10.18502/japh.v6i1.7601 ◽

2021 ◽

Author(s):

Zahra Namvar ◽

Mostafa Hadei ◽

Seyed Saeed Hashemi ◽

Elahe Shahhosseini ◽

Philip K. Hopke ◽

...

Keyword(s):

Air Pollution ◽

Air Pollutants ◽

Hospital Admissions ◽

Respiratory Infections ◽

Positive Association ◽

Ambient Air ◽

Age Group ◽

Distributed Lag ◽

Ambient Air Pollutants ◽

Short Term Exposure

Introduction: Air pollution is one of the main causes for the significant increase of respiratory infections in Tehran. In the present study, we investigated the associations between short-term exposure to ambient air pollutants with the hospital admissions and deaths. Materials and methods: Health data from 39915 hospital admissions and 2459 registered deaths associated with these hospital admissions for respiratory infections were obtained from the Ministry of Health and Medical Education during 2014-2017. We used the distributed lag non-linear model (DLNM) for the analyses. Results: There was a statistically positive association between PM2.5 and AURI in the age group of 16 years and younger at lags 6 (RR 1.31; 1.05-1.64) and 7 (RR 1.50; 1.09-2.06). AURI admissions was associated with O3 in the age group of 16 and 65 years at lag 7 with RR 1.13 (1.00-1.27). ALRI admissions was associated with CO in the age group of 65 years and older at lag 0 with RR 1.12 (1.02-1.23). PM10 was associated with ALRI daily hospital admissions at lag 0 for males. ALRI admissions were associated with NO2 for females at lag 0. There was a positive association between ALRI deaths and SO2 in the age group of 65 years and older at lags 4 and 5 with RR 1.04 (1.00-1.09) and 1.03 (1.00-1.07), respectively. Conclusion: Exposure to outdoor air pollutants including PM10, PM2.5, SO2, NO2, O3, and CO was associated with hospital admissions for AURI and ALRI at different lags. Moreover, exposure to SO2 was associated with deaths for ALRI.

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Short-Term Effects of Ambient Air Pollution on Hospitalization for Respiratory Disease in Taiyuan, China: A Time-Series Analysis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph15102160 ◽

2018 ◽

Vol 15 (10) ◽

pp. 2160 ◽

Cited By ~ 14

Author(s):

Lisha Luo ◽

Yunquan Zhang ◽

Junfeng Jiang ◽

Hanghang Luan ◽

Chuanhua Yu ◽

...

Keyword(s):

Air Pollution ◽

Time Series ◽

Respiratory Disease ◽

Air Pollutants ◽

Ambient Air ◽

Ambient Air Pollution ◽

High Risk Population ◽

Short Term ◽

Ambient Air Pollutants ◽

Short Term Effects

In this study, we estimated the short-term effects of ambient air pollution on respiratory disease hospitalization in Taiyuan, China. Daily data of respiratory disease hospitalization, daily concentration of ambient air pollutants and meteorological factors from 1 October 2014 to 30 September 2017 in Taiyuan were included in our study. We conducted a time-series study design and applied a generalized additive model to evaluate the association between every 10-μg/m3 increment of air pollutants and percent increase of respiratory disease hospitalization. A total of 127,565 respiratory disease hospitalization cases were included in this study during the present period. In single-pollutant models, the effect values in multi-day lags were greater than those in single-day lags. PM2.5 at lag02 days, SO2 at lag03 days, PM10 and NO2 at lag05 days were observed to be strongly and significantly associated with respiratory disease hospitalization. No significant association was found between O3 and respiratory disease hospitalization. SO2 and NO2 were still significantly associated with hospitalization after adjusting for PM2.5 or PM10 into two-pollutant models. Females and younger population for respiratory disease were more vulnerable to air pollution than males and older groups. Therefore, some effective measures should be taken to strengthen the management of the ambient air pollutants, especially SO2 and NO2, and to enhance the protection of the high-risk population from air pollutants, thereby reducing the burden of respiratory disease caused by ambient air pollution.

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Short-term joint effects of ambient air pollutants on emergency department visits for respiratory and circulatory diseases in Colombia, 2011–2014

Environmental Pollution ◽

10.1016/j.envpol.2019.02.028 ◽

2019 ◽

Vol 248 ◽

pp. 380-387 ◽

Cited By ~ 9

Author(s):

Laura Andrea Rodríguez-Villamizar ◽

Néstor Yezid Rojas-Roa ◽

Julián Alfredo Fernández-Niño

Keyword(s):

Emergency Department ◽

Air Pollutants ◽

Ambient Air ◽

Emergency Department Visits ◽

Short Term ◽

Joint Effects ◽

Ambient Air Pollutants ◽

Circulatory Diseases

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Short-term effects of air pollution on blood pressure

Scientific Reports ◽

10.1038/s41598-019-56413-y ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 1

Author(s):

You-Jung Choi ◽

Sun-Hwa Kim ◽

Si-Hyuck Kang ◽

Sun-Young Kim ◽

Ok-Jin Kim ◽

...

Keyword(s):

Blood Pressure ◽

Air Pollution ◽

Air Pollutants ◽

Ambient Air ◽

Ambient Air Pollution ◽

Pathophysiological Mechanism ◽

Short Term ◽

Mortality And Morbidity ◽

Short Term Exposure ◽

Increased Risk

AbstractElevated blood pressure (BP) has been proposed as a possible pathophysiological mechanism linking exposure to ambient air pollution and the increased risk of cardiovascular mortality and morbidity. In this study, we investigated the hourly relationship between ambient air pollutants and BP. BP measurements were extracted from the electronic health record database of the Seoul National University Bundang Hospital from February 2015 to June 2017. A total of 98,577 individual BP measurements were matched to the hourly levels of air pollutants. A generalized additive model was constructed for hour lags of 0–8 of air pollutants adjusting for age, sex, meteorological variables, and time trend. Systolic BP was shown to be significantly lower at 2–4 hours and 3–5 hours after increased levels of SO2 and CO, respectively (0.24 mmHg and 0.26 mmHg for an interquartile range, respectively). In contrast, O3 and NO2 were associated with significantly increased systolic BP at 3–5 lag hours and at 0–2 lag hours, respectively. BP elevation in association with O3 and NO2 was shown to be significantly greater in hypertensive patients than normotensive subjects. Our findings suggest that short-term exposure to air pollution may be associated with elevated BP.

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