A video-based discussion of movement disorders in paediatric anti NMDAR encephalitis: A case series from Eastern India

Author(s):  
Amlan Kusum Datta ◽  
Prakash Chandra Ghosh ◽  
Mitali Bera ◽  
Adreesh Mukherjee ◽  
Jasodhara Chaudhuri ◽  
...  
2014 ◽  
Vol 1 ◽  
pp. 92-100 ◽  
Author(s):  
Anna Potulska-Chromik ◽  
Monika Rudzinska ◽  
Monika Nojszewska ◽  
Aleksandra Podlecka-Piętowska ◽  
Andrzej Szczudlik ◽  
...  

2019 ◽  
Vol 31 (2) ◽  
pp. 195-200
Author(s):  
Mohammad Reza Akbari ◽  
Arash Mirmohammadsadeghi ◽  
Ali Makateb ◽  
Fariba Ghassemi ◽  
Amir Hossein Norooznezhad ◽  
...  

2017 ◽  
Vol 13 (04) ◽  
pp. 319-322
Author(s):  
Susrita Banerjee ◽  
Satyabrata Roychowdhuri ◽  
Mihir Sarkar

AbstractWe present four cases of pediatric scrub typhus from a tertiary care center of eastern India, emphasizing on varied unusual clinical manifestations posing diagnostic difficulties. A low index of suspicion is required to prevent under diagnosis. We report a case series of four patients with scrub typhus having uncommon clinical manifestations (two patients with hemophagocytic lymphohistiocytosis, one patient with myocarditis, and one patient presenting with shock reminiscent of dengue shock syndrome). The response to doxycycline was good, with fever subsiding within 48 to 72 hours of starting the treatment. Three out of four cases completely recovered once appropriate medication was given.


Cephalalgia ◽  
2014 ◽  
Vol 34 (14) ◽  
pp. 1134-1141 ◽  
Author(s):  
Bahram Mokri

Importance and Objective Headache is the most common symptom in spontaneous CSF leaks, frequently associated with additional manifestations. Herein, attention is drawn to movement disorder as a notable manifestation of spontaneous CSF leaks. Design Four women and one man (ages 51–78 years) with spontaneous CSF leaks and movement disorders were evaluated clinically and by pertinent neuroimaging studies with follow-up of one to seven years (mean 3.2 years). Results The movement disorder consisted of choreiform movements in two patients, torticollis in one, mixed tremor in one, and parkinsonism in one. All except the last patient had headaches (orthostatic in one, Valsalva maneuver-induced in one, both orthostatic and Valsalva-induced in two, lingering low-grade headache in one). Diffuse pachymeningeal enhancement and sinking of the brain was noted in all. CT-myelography showed definite CSF leak in three and equivocal leak in one, while no leak could be located in the fifth patient. Two patients improved over time with complete resolution of the movement disorder. One responded to epidural blood patch with complete resolution of his choreiform movements. Two patients required surgery and epidural blood patches. Results were drastic but nondurable in one, while complete recovery was achieved in the other. Conclusion Movement disorders are uncommon in spontaneous CSF leaks but occasionally can be one of the major components of the clinical presentation.


2016 ◽  
Vol 22 (8) ◽  
pp. 828-838 ◽  
Author(s):  
Gemma L. McKeon ◽  
James G. Scott ◽  
Donna M. Spooner ◽  
Alexander E. Ryan ◽  
Stefan Blum ◽  
...  

AbstractBackground: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently described life-threatening autoimmune disorder associated with a characteristic multi-stage neuropsychiatric syndrome. Although it is known that the majority of patients experience neuropsychological disturbance post-treatment, some aspects of the cognitive profile remain unclear. Methods: This study sought to investigate patterns of cognitive functioning in a sample of anti-NMDAR encephalitis patients. Seven (6F:1M; mean age, 26.4 years; range, 16–37 years) treated patients completed a comprehensive set of neurocognitive and social functioning measures. Performance was analyzed using normative data (where available), and comparison with matched controls (10F:4M; mean age, 25.8 years; range, 16–38 years). Results: Individual cognitive profiles ranged from within normal limits to extensive dysfunction. Relative to controls, the patient group’s performance was affected in the domains of verbal/ visual memory, working memory, attention, processing speed, executive functioning, and social cognition. The patient group also reported significantly higher levels of anxiety compared to controls. Conclusions: These results add to the accumulating evidence that neurocognitive deficits, consistent with the distribution and functions of the NMDAR system can persist during recovery from anti-NMDAR encephalitis. This is the first study to provide evidence of performance decrements on measures of social cognition, including some involving theory of mind. (JINS, 2016, 22, 828–838)


2021 ◽  
pp. 10.1212/CPJ.0000000000001082
Author(s):  
Mariam Hull ◽  
Mered Parnes ◽  
Joseph Jankovic

Abstract:Background:Functional (psychogenic) movement disorders (FMDs) are conditions in which affected patients develop abnormal movements that are incongruous with known, organic, movement disorders, often associated with psychological stressors.Methods:In this case series, electronic medical records of all patients who presented to our adult and pediatric tertiary-care movement disorders clinics between March 1 and October 30, 2020 and during the same period in 2019 were reviewed. All patients diagnosed with functional or psychogenic movement disorder were included if they satisfied diagnostic criteria.Results:Among 550 new patients referred for evaluation at our tertiary care movement disorders centers, 45 (8.2%) received a diagnosis of FMD; 75.6% were female, in comparison to the prior year during which time 665 new patients were evaluated and 5.1% were diagnosed with FMD. This represents a 60.1% increase (90.1% in pediatric cohort, 50.9% in adult cohort) in new patients diagnosed with FMD during the COVID-19 pandemic.Conclusions:Within our patient population, there has been increased incidence of FMDs in the setting of the COVID-19 pandemic, possibly reflecting increased psychological and other stressors during this period.


2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Sibabratta Patnaik ◽  
MukeshKumar Jain ◽  
NikunjKishore Rout ◽  
AmitRanjan Rup ◽  
ChinmayKumar Behera ◽  
...  

2019 ◽  
Vol 9 (2) ◽  
pp. 146
Author(s):  
S. Pandey ◽  
S. Ghosh ◽  
P. Halder ◽  
D. Pal ◽  
D. Modak ◽  
...  

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