Abstract. We have developed an integrated tool of assessment that can be used for evaluating the public health costs caused by the concentrations of fine particulate matter (PM2.5) in ambient air. The model can be used in assessing the impacts of various alternative air quality abatement measures, policies and strategies. The model has been applied for the evaluation of the costs of the domestic emissions that influence the concentrations of PM2.5 in Finland in 2015. The model includes the impacts on human health; however, it does not address the impacts on climate change or the state of the environment. First, the national Finnish emissions were evaluated using the Finnish Regional Emission Scenarios model (FRES) on a resolution of 250 × 250 m2 for the whole of Finland. Second, the atmospheric dispersion was analyzed by using the chemical transport model SILAM and the source-receptor matrices contained in the FRES model. Third, the health impacts were assessed by combining the spatially resolved concentration and population datasets, and by analyzing the impacts for various health outcomes. Fourth, the economic impacts for the health outcomes were evaluated. The model can be used to evaluate the costs of the health damages for various emission source categories, for a unit of emissions of PM2.5. It was found that economically the most effective measures would be the reduction of the emissions in urban areas of (i) road transport, (ii) non-road vehicles and machinery, and (iii) residential wood combustion. The reduction of the precursor emissions of PM2.5 was clearly less effective, compared with reducing directly the emissions of PM2.5. We have also designed a user-friendly web-based tool of assessment that is available open access.