Constitutive activation of the jasmonate signaling pathway enhances the production of secondary metabolites in tomato

FEBS Letters ◽  
2006 ◽  
Vol 580 (11) ◽  
pp. 2540-2546 ◽  
Author(s):  
Hui Chen ◽  
A. Daniel Jones ◽  
Gregg A. Howe
Keyword(s):  
Secondary Metabolites ◽  
Signaling Pathway ◽  
Constitutive Activation ◽  
Jasmonate Signaling

Recent Trends in Jasmonate Signaling Pathway

2013 ◽  
pp. 277-290 ◽  
Author(s):  
Tariq Ahmad Dar ◽  
Moinuddin ◽  
Nadeem Hashmi ◽  
Mohd Idrees ◽  
Akbar Ali
Keyword(s):  
Signaling Pathway ◽  
Jasmonate Signaling ◽  
Recent Trends

scholarly journals Brn-2 Expression Controls Melanoma Proliferation and Is Directly Regulated by β-Catenin

2004 ◽  
Vol 24 (7) ◽  
pp. 2915-2922 ◽  
Author(s):  
Jane Goodall ◽  
Silvia Martinozzi ◽  
Timothy J. Dexter ◽  
Delphine Champeval ◽  
Suzanne Carreira ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Transcription Factor ◽  
Signaling Pathway ◽  
Target Genes ◽  
Constitutive Activation ◽  
Pou Domain ◽  
Common Cancer ◽  
Interfering Rna ◽  
Melanoma Cell Lines

ABSTRACT Constitutive activation of the Wnt/β-catenin signaling pathway is a notable feature of a large minority of cases of malignant melanoma, an aggressive and increasingly common cancer. The identification of target genes downstream from this pathway is therefore crucial to our understanding of the disease. The POU domain transcription factor Brn-2 has been implicated in control of proliferation and melanoma survival, and its expression is strongly upregulated in melanoma. We show here that in vivo Brn-2 is expressed in melanocytes but not in embryonic day 11.5 melanoblasts and that its expression is directly controlled by the Wnt/β-catenin signaling pathway in melanoma cell lines and in transgenic mice. Moreover, silent interfering RNA-mediated inhibition of Brn-2 expression in melanoma cells overexpressing β-catenin results in significantly decreased proliferation. These results, together with the observation that BRAF signaling also induces Brn-2 expression, reveal that Brn-2 is a focus for the convergence of two key melanoma-associated signaling pathways that are linked to cell proliferation.

scholarly journals Transient pulse formation in jasmonate signaling pathway

2011 ◽  
Vol 273 (1) ◽  
pp. 188-196 ◽  
Author(s):  
Subhasis Banerjee ◽  
Indrani Bose
Keyword(s):  
Signaling Pathway ◽  
Jasmonate Signaling ◽  
Pulse Formation
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