Formulating orange oil-in-water beverage emulsions for effective delivery of bioactives: Improvements in chemical stability, antioxidant activity and gastrointestinal fate of lycopene using carrier oils

Abstract Subcritical water was used to provide propolis oil in water (O/W) nanoemulsions. To monitor and detect the main bioactive compounds of the prepared propolis extract, gas chromatography demonstrated that there were 47 bioactive materials in the propolis extract, among which pinostrobin chalcone and pinocembrin were the two key components. Effectiveness of two processing parameters such as the amount of saponin (0.5–2.0 g) and propolis extract (0.1–0.6 g), on particle size, polydispersity index (PDI), zeta potential, and antioxidant activity of the provided nanoemulsions, was evaluated. Results demonstrated that more desirable propolis O/W nanoemulsion, with minimum particle size (144.06 nm) and PDI (0.286), and maximum zeta potential (−21.71 mV) and antioxidant activity (90.86%) were made using 0.50 g of saponin and 0.53 g of propolis extract. Further analysis revealed that the prepared nanoemulsion based on optimum processing conditions had spherical shaped propolis nanodroplets in the colloidal solution with turbidity and maximum broad absorption peak of 0.08 a.u. and 292 nm, respectively. The prepared nanoemulsion had high antibacterial activity against both selected bacteria strains namely, Staphylococcus aureus and Escherichia coli.

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Astaxanthin–garlic oil nanoemulsions preparation using spontaneous microemulsification technique: optimization and their physico–chemical properties

Zeitschrift für Physikalische Chemie ◽

10.1515/zpch-2019-1545 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Seyedalireza Mortazavi Tabrizi ◽

Afshin Javadi ◽

Navideh Anarjan ◽

Seyyed Javid Mortazavi Tabrizi ◽

Hamid Mirzaei

Keyword(s):

Antioxidant Activity ◽

Particle Size ◽

Subcritical Water ◽

Chemical Properties ◽

Polydispersity Index ◽

Garlic Oil ◽

Physico Chemical ◽

Minimum Particle Size ◽

Oil In Water ◽

Technique Optimization

AbstractGarlic oil in water nanoemulsion was resulted through subcritical water method (temperature of 120 °C and pressure of 1.5 bar, for 2 h), using aponin, as emulsifier. Based on the prepared garlic oil nanoemulsion, astaxanthin–garlic oil nanoemulsions were prepared using spontaneous microemulsification technique. Response surface methodology was employed to evaluate the effects of independent variables namely, amount of garlic oil nanoemulsion (1–9 mL) and amount of provided astaxanthin powder (1–9 g) on particle size and polydispersity index (PDI) of the resulted nanoemulsions. Results of optimization indicated that well dispersed and spherical nanodroplets were formed in the nanoemulsions with minimum particle size (76 nm) and polydispersity index (PDI, 0.358) and maximum zeta potential value (−8.01 mV), using garlic oil nanoemulsion amount of 8.27 mL and 4.15 g of astaxanthin powder. Strong antioxidant activity (>100%) of the prepared astaxanthin–garlic oil nanoemulsion, using obtained optimum amounts of the components, could be related to the highest antioxidant activity of the colloidal astaxanthin (>100%) as compared to that of the garlic oil nanoemulsion (16.4%). However, higher bactericidal activity of the resulted nanoemulsion against Escherichia coli and Staphylococcus aureus, were related to the main sulfur bioactive components of the garlic oil in which their main functional groups were detected by Fourier transform-infrared spectroscopy.

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Antioxidant Activity of Seaweed Extracts: In Vitro Assays, Evaluation in 5 % Fish Oil-in-Water Emulsions and Characterization

Journal of the American Oil Chemists Society ◽

10.1007/s11746-015-2624-5 ◽

2015 ◽

Vol 92 (4) ◽

pp. 571-587 ◽

Cited By ~ 14

Author(s):

K. H. Sabeena Farvin ◽

Charlotte Jacobsen

Keyword(s):

Antioxidant Activity ◽

Fish Oil ◽

In Vitro Assays ◽

Seaweed Extracts ◽

Oil In Water

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PENENTUAN STABILITAS SEDIAAN KRIM TABIR SURYA DARI BAHAN EKSTRAK RIMPANG KENCUR (Kaempferia galanga L.)

Journal of Biological Researches ◽

10.23869/bphjbr.10.2.20055 ◽

2005 ◽

Vol 10 (2) ◽

pp. 103-105

Author(s):

Widji Soeratri ◽

Noor Ifansyah ◽

Diana Fitrianingrum

Keyword(s):

Chemical Stability ◽

Room Temperature ◽

Percolation Method ◽

Kaempferia Galanga ◽

Oil In Water ◽

Water Base

The objective of this research was to know the chemical stability of the etil para-metoksi sinamat (EPMS) formulated in sunscreen cream of oil in water base. The EPMS was isolated from Kaempferia galanga L. tuber pulvis with maceration-percolation method using ethanol 96 percent. The chemical stability of the EPMS formulated in sunscreen cream of the oil in water base was investigated by keeping the cream at room temperature. At appropriate interval the concentration of EPMS in cream was measured. The results showed that the EPMS formulated in sunscreen cream of oil in water base was unstable at room temperature for 70 days. The concentration of EPMS in cream significantly decreased after 70 days (p = 0,01) during keeping at room temperature with the coefficient degradation value (k)= 4.4.10-3/day.

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Enhancement of Chemical Stability and Dermal Delivery of Cordyceps militaris Extracts by Nanoemulsion

Nanomaterials ◽

10.3390/nano10081565 ◽

2020 ◽

Vol 10 (8) ◽

pp. 1565 ◽

Cited By ~ 1

Author(s):

Pachabadee Marsup ◽

Kankanit Yeerong ◽

Waranya Neimkhum ◽

Jakkapan Sirithunyalug ◽

Songyot Anuchapreeda ◽

...

Keyword(s):

Antioxidant Activity ◽

Chemical Stability ◽

Radical Scavenging Activity ◽

Skin Irritation ◽

Radical Scavenging ◽

Water Extract ◽

Cordyceps Militaris ◽

Alpha Tocopherol ◽

Dermal Delivery ◽

The Stability

This study aimed to develop nanoemulsions for enhancing chemical stability and dermal delivery of Cordyceps militaris extracts. C. militaris was extracted by maceration and infusion. The extracts were investigated for cordycepin, phenolic, and flavonoid content. The antioxidant activity was investigated by in vitro spectrophotometric methods. The irritation profile was investigated by hen’s egg-chorioallantoic membrane test. Nanoemulsions were developed using high-pressure homogenizer. C. militaris extract was incorporated into the nanoemulsion and investigated for safety, release profile, permeation, and skin retention. The results demonstrated that water extract (CW) contained the significantly highest content of cordycepin, phenolics, and flavonoids, which were responsible for antioxidant activity. CW was the most potent antioxidant. CW possessed comparable 2,2′-diphenyl-1-picrylhydrazyl radical scavenging activity and lipid peroxidation inhibition to l-ascorbic acid (96.9 ± 3.1%) and alpha-tocopherol (87.2 ± 1.0%). Consequently, ten mg/mL of CW was incorporated into nanoemulsions composing of sugar squalene, Tween® 85, and deionized water. Nanoemulsion, which had the smallest internal droplet size (157.1 ± 2.6 nm), enhanced the stability of CW, had no cytotoxicity effect and no skin irritation, released the most CW (0.9 ± 0.0% w/w after 24 h), and delivered the highest CW into the skin layer (33.5 ± 0.7% w/w). Therefore, nanoemulsion was suggested for enhancing the stability and dermal delivery of CW.

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