scholarly journals An updated knowledge of Black seed (Nigella sativa Linn.): Review of phytochemical constituents and pharmacological properties

2021 ◽  
Vol 25 ◽  
pp. 100404 ◽  
Author(s):  
Md Faruque Ahmad ◽  
Fakhruddin Ali Ahmad ◽  
Syed Amir Ashraf ◽  
Hisham H. Saad ◽  
Shadma Wahab ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Pharmacological Properties ◽  
Black Seed ◽  
Phytochemical Constituents

scholarly journals Nigella sativa (Kalonji): A Black Seed of Miracle

2021 ◽  
Vol 8 (4) ◽  
pp. 342-357
Author(s):  
Shifali Thakur ◽  
Hemlata Kaurav ◽  
Gitika Chaudhary
Keyword(s):  
Nigella Sativa ◽  
Chemical Constituents ◽  
Acne Vulgaris ◽  
World Health ◽  
Pharmacological Properties ◽  
Gulf Region ◽  
Medicinal Uses ◽  
Black Cumin ◽  
Black Seed ◽  
Wide Range

It is recommended by the World health organization (WHO) that most of the world's population depends on herbal medicine for their health care. Nigella sativa is commonly known as a Black seed, Black cumin or 'Habbatul Barakah' i.e. an annual herb possessing a wide range of medicinal uses apart from its commercial significance as a spice yielding plant. It has long been used in the folk medicine system of the Arabian Gulf region, Far East Asia, and Europe. Seeds and oils of N. Sativa are the primary medicinal source from ancient times. It is one of the most common herbal plants used worldwide and possesses various chemical constituents such as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellicine, nigllimine, nigellidine, and alpha-hederin. There are more than 100 constituents isolated from the plant. These chemical compounds have many pharmacological activities such as antibacterial, antiviral, anti-inflammatory, wound healing effect and also for acne vulgaris, skin cancer, pigmentation and many other cosmeceutical properties. Much scientific research on N. sativa has been conducted over the last five decades to investigate chemical and pharmacological properties. In this review, the phytochemicals, pharmacological properties, Ayurvedic properties and folk uses of Nigella sativa are briefly explained. Keywords: Nigella sativa, Kalonji, Antinephrotic, Immunomodulary, Black cumin.

Therapeutic perspectives of the black cumin component thymoquinone: A review

2021 ◽  
Author(s):  
Chandan Sarkar ◽  
Sarmin Jamaddar ◽  
Tawhida Islam ◽  
Milon Mondal ◽  
Muhammad Torequl Islam ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Nigella Sativa ◽  
Pharmacological Properties ◽  
Black Cumin

The dietary phytochemical thymoquinone, obtained from the black and angular seeds of Nigella sativa, is a promising monoterpenoid hydrocarbons, which has been receiving massive attention for its therapeutic potential and pharmacological properties.

scholarly journals Dietary Black Seed Effects on Growth Performance, Proximate Composition, Antioxidant and Histo-Biochemical Parameters of a Culturable Fish, Rohu (Labeo rohita)

Animals ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 48
Author(s):  
Maria Latif ◽  
Mehwish Faheem ◽  
Asmatullah ◽  
Seyed Hossein Hoseinifar ◽  
Hien Van Doan
Keyword(s):  
Growth Performance ◽  
Proximate Composition ◽  
Biochemical Parameters ◽  
Reduced Glutathione ◽  
Labeo Rohita ◽  
Nigella Sativa ◽  
Growth Promoter ◽  
Feeding Trial ◽  
Glutathione S Transferase ◽  
Black Seed

This feeding trial was conducted to investigate the effects of dietary black seed (Nigella sativa) supplementation on the growth performance, muscles proximate composition, antioxidant and histo-biochemical parameters of rohu (Labeo rohita). Fingerlings (8.503 ± 0.009 g) were fed on 0.0%, 1% and 2.5% black seed supplemented diets for 28 days. Fish sampling was done on the 7th, 14th, 21st and 28th day of experiment. The results of the present study indicated that black seed supplementation significantly increased growth performance and muscles protein contents of rohu over un-supplemented ones. Lipid peroxidation levels significantly decreased in all the studied tissues (liver, gills, kidney and brain) of black seed fed rohu, whereas the antioxidant enzymes (catalase, glutathione-S-transferase, glutathione peroxidase and reduced glutathione) activities were increased in all the studied tissues of black seed supplemented rohu at each sampling day. The hepatic-nephric marker enzymes levels were decreased for black seed fed rohu. The present study showed that tested black seed levels are safe for rohu. Black seed is cheaply available in local markets of Pakistan; therefore, based on the results of the present study, it is suggested that black seed has potential to be used as natural growth promoter and antioxidant in the diet of rohu.

scholarly journals Effect of Black Seed (Nigella sativa) and Uziza (Piper guineense) Leaf on the Histology of the Liver of Wistar Albino Rats

2019 ◽  
pp. 1-11
Author(s):  
Okoye Ngozi Franca ◽  
Ikiriko, Favour Ibiwari
Keyword(s):  
Aqueous Extract ◽  
Nigella Sativa ◽  
Positive Control ◽  
Negative Control ◽  
Positive Control Group ◽  
Control Group ◽  
Dependent Manner ◽  
Piper Guineense ◽  
The Third ◽  
Black Seed

Aim: This study was aimed at investigating the effects of aqueous extracts of both Nigella sativa and Piper guineense on the liver enzymes; alanine amino transferase (ALT), aspartate amino transferase (AST) and alkaline phosphatase (ALP). Also the effect of Nigella sativa and Piper guineense extracts on the histology of the liver of Wistar rat was also studied. Materials and Methods: A total of twenty five Wistar rats were used for the study. The animals were grouped into five groups, each having five animals. They were induced with sucrose and margarine to cause high sugar levels and hyperlipidemia respectively except the positive control group which was fed normal feed. The groups were: the positive control group, the negative control group which were induced without treatment, the uziza leaf group which were induced and were treated with 2 ml of aqueous extract of uziza leaf, the black seed group which were induced and were treated with 2 ml of aqueous extract of black seed, and the black seed and uziza group which were induced and were treated with 2ml of aqueous extract of black seed and 2 ml of aqueous extract of uziza leaf.  Results: The result showed that the extracts decreased the ALT and AST and ALP activities in the rats in a time dependent manner with highest decrease obtained on the third week of treatment with the extracts.  The ALT activity (U/L) on the third week of treatment showed for the, negative control (64.48 ± 0.22), uziza leaf (28.82 ± 0.12), black seed (32.65 ± 0.02), black seed and uziza leaf (16.04 ± 0.02) (p≤0.05). The decrease in activity for AST levels (U/L) on the third week of treatment, showed for the negative control (58.00 ± 0.02), uziza leaf (11.00 ± 0.01), black seed (12.00 ± 0.02), black seed and uziza leaf (8.00 ± 0.02). Conclusion: It can be concluded that both uziza leaf and black seed have hepatoprotective effect on the liver.

scholarly journals Calotropis procera (Arka): A Tribal Herb of Utmost Significance

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Isha Kumari ◽  
Gitika Chaudhary
Keyword(s):  
Medicinal Plants ◽  
Review Article ◽  
Calotropis Procera ◽  
Pharmacological Properties ◽  
The Family ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
The Rich ◽  
The Tropics ◽  
Important Medicinal Plant

Nature has gifted humans a vast variety of medicinal plants, which are the rich source of bioactive compounds. Calotropis procera is an important medicinal plant that belongs to the family asclepiadaceae. It is commonly known as madar and milkweed plant in english and arka in hindi. It is mostly found in the tropics of asia and africa. Calotropis procera is a highly valued plant in the folk medication system. Each part of the plant is richly endowed with diverse nature of phytochemical constituents like alkaloids, proteins, vitamins, carbohydrates, saponins, terpenes, and flavonoids, etc. These phytochemicals are significantly associated with various therapeutic and pharmacological properties such as anti-microbial, anti-oxidant, anti-inflammatory, anti-ulcer, antifertility, anti-diarrheal, and spasmolytic. In this review article, the therapeutic and pharmacological value of this important plant has been summarized along with its utilization in the folklore and ayurvedic medicinal system.

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