Auditory neuropathy spectrum disorder: Its prevalence and audiological characteristics in an Indian tertiary care hospital

2012 ◽  
Vol 76 (9) ◽  
pp. 1351-1354 ◽  
Author(s):  
Ruchika Mittal ◽  
A.V. Ramesh ◽  
S.S. Panwar ◽  
Ajith Nilkanthan ◽  
Satish Nair ◽  
...  
2020 ◽  
Vol 1 (1) ◽  
pp. 5
Author(s):  
Anum Farooq ◽  
Shoaib Ahmed

Objective: To investigate the frequency of Autistic Spectrum Disorder (ASD) by screening 16 to 30 months old children, reporting to a tertiary care hospital. Study Design: Cross sectional study.Place and Duration of Study: The study was conducted in the Paediatrics Outpatient Department of Military Hospital, Rawalpindi from November 2017 to August 2018.Materials and Methods: A total of 163 children between the age of 16-30 months were screened using Urdu translated version of Modified Checklist for Autism in Toddlers, revised with Follow-Up (M-CHAT-R/FTM). Those who screened positive on MCHAT-R were assessed using Childhood Autism Rating Scale-2 (CARS 2) and Diagnostic and Statistical Manual-5 (DSM-5) as diagnostic tools.Results: Among the 163 children screened with MCHAT, 33 were found positive for autism. The positive individuals were further assessed on CARS-2 and DSM-5; five children were diagnosed with ASD at moderate to severe level.  This study has shown that 3% of children visiting the hospital for various reasons suffer from ASD.Conclusion: This study concluded that 3% of the children coming to the hospital for any purpose were found to have ASD. There is a need to make Level 1 screening an essential part of regular check-ups of children in Paediatrics outpatient clinics. How to cite this: Farooq A, Ahmed S. Screening for Autism Spectrum Disorder in Children up to Age 2.5 years in a Tertiary Care Hospital. Life and Science. 2020; 1(1): 12-16.  doi: http://doi.org/10.37185/L&S.1.1.74


Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

Author(s):  
Vinod Kumar ◽  
Bhupen Songra ◽  
Richa Jain ◽  
Deeksha Mehta

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.


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