scholarly journals Safe-by-Design part I: Proposal for nanospecific human health safety aspects needed along the innovation process

NanoImpact ◽  
2020 ◽  
Vol 18 ◽  
pp. 100227 ◽  
Author(s):  
Susan Dekkers ◽  
Susan W.P. Wijnhoven ◽  
Hedwig M. Braakhuis ◽  
Lya G. Soeteman-Hernandez ◽  
Adrienne J.A.M. Sips ◽  
...  
2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Mary Gulumian ◽  
Flemming R. Cassee

AbstractSafe-by-Design (SbD) has been put forward as a concept to assure that only safe nanomaterials will reach the market and that safety aspects have already been considered in a very early stage of the innovation process. In practice, several laboratory test have been proposed to screen newly developed nanomaterials and nano-enabled products to assess their hazardous nature. These tests need to have sufficient predictive power for possible adverse effects on human health, not only due to acute (peak) exposures, but also for long-term (low dose) exposures as these materials may accumulate over time in organs and tissues.


NanoImpact ◽  
2021 ◽  
pp. 100354
Author(s):  
Isabella Tavernaro ◽  
Susan Dekkers ◽  
Lya G. Soeteman-Hernández ◽  
Petra Herbeck-Engel ◽  
Cornelle Noorlander ◽  
...  

NanoImpact ◽  
2020 ◽  
Vol 18 ◽  
pp. 100224 ◽  
Author(s):  
Zhangjian Chen ◽  
Shuo Han ◽  
Shupei Zhou ◽  
Huimin Feng ◽  
Ying Liu ◽  
...  

2021 ◽  
Author(s):  
Gabriel Mihaita Daraban ◽  
Raluca Maria Hlihor ◽  
Maria Apostol ◽  
Marinela Badeanu ◽  
Daniela Suteu

2019 ◽  
Vol 15 ◽  
pp. 02024
Author(s):  
G.-D. Dumitriu (Gabur) ◽  
C. Teodosiu ◽  
I. Morosanu ◽  
O. Jitar ◽  
V.V. Cotea

Heavy metals in beverages can constitute serious problems to human health. Consumption of wine may contribute to the daily dietary intake of pollutants, especially of toxic (heavy) metals. These compounds are also known as priority pollutants due to their potential toxic effects, if concentrations are not kept under allowable limits. Many characteristics such as: quality, origin, aroma and health safety of wine are influenced by environmental and anthropogenic factors. Hence, the contamination of wine by priority pollutants may occur at different stages of vine-growing, due to the application of agricultural chemicals, or at different stage of winemaking and ageing, because of the extended contact of wine with winemaking equipment materials (aluminium, brass, glass, stainless steel and wood, etc.), or chemicals used for cleaning and sanitation. The aim of this study is to identify and quantify the heavy metal ions from red wines. A particular focus was attributed to Zn and Cd from destemming-pressing-filtration-bottling stages in Fetească neagră grape variety from Cotnari vine growing region of Romania. Results indicated that heavy metals were linked to diverse Zn and Cd sources and complexes during the winemaking processes. Concentration of Zn and Cd were generally higher in must than in wine, although heavy metals concentrations were lower than the limits recommended by the International Organization of Vine and Wine for human health safety.


Toxicology ◽  
2020 ◽  
Vol 436 ◽  
pp. 152421 ◽  
Author(s):  
Vera Rogiers ◽  
Emilio Benfenati ◽  
Ulrike Bernauer ◽  
Laurent Bodin ◽  
Paul Carmichael ◽  
...  
Keyword(s):  
The Eu ◽  

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