28364 Efficacy of deep cleansing gel containing 2% salicylic acid, 0.2% zinc gluconate, and 0.05% lipohydroxyacid as monotherapy to treat mild to moderate facial acne vulgaris

2021 ◽  
Vol 85 (3) ◽  
pp. AB185
Author(s):  
Loan Towersey ◽  
Clarice Caixeta ◽  
Roderick James Hay ◽  
Brigitte Drenó ◽  
Sophie Seité ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Acne Vulgaris ◽  
Zinc Gluconate ◽  
Facial Acne

scholarly journals Glycolic Acid, Lactic Acid, Mandelic Acid, Salicylic Acid, Citric Acid, Gluconolactone: Skin Exfoliators in Combination Therapy of Acne Vulgaris

2020 ◽  
Vol 3 (10) ◽  
pp. 54-55
Author(s):  
Vishal Saxena ◽  
Krishana Yadav
Keyword(s):  
Salicylic Acid ◽  
Mandelic Acid ◽  
Glycolic Acid ◽  
Research Study ◽  
Acne Vulgaris ◽  
Hydroxy Acids ◽  
Skin Texture ◽  
Severe Acne ◽  
Alpha Hydroxy Acids ◽  
Facial Acne

Facial acne are a recurring issue in most of the population and can cause disturbing skin issues. A combination of Alpha-hydroxy acids, Beta-hydroxy-acids and Poly-hydroxy acids has become popular for treating acne vulgaris in last few years. The main objective of this research study is to evaluate the efficacy & safety of combination of these acids in the treatment of acne vulgaris. The study was conducted on 12 volunteers having mild to moderate to severe acne. They were divided into 3 groups according to the severity of their facial acne. Members of each group were treated with a series of 30% AHA, 2% BHA and 7% PHA. The improvement in their acne condition as well as skin texture was assessed over a period of 6 weeks.

scholarly journals Lack of association in acne and salivary testosterone

2018 ◽  
Vol 4 (1) ◽  
pp. 1-5
Author(s):  
David Fresnais ◽  
Edvin Ingberg ◽  
Elvar Theodorsson ◽  
Jakob O Ström
Keyword(s):  
Acne Vulgaris ◽  
Daily Basis ◽  
Enzyme Linked Immunosorbent Assay ◽  
Weak Correlation ◽  
Salivary Testosterone ◽  
Weak Association ◽  
The Individual ◽  
Actual Relation ◽  
Facial Acne ◽  
Monotonic Relation

The pathogenesis of acne vulgaris has only been partially elucidated. Various hormones, especially androgens, are likely to play a role, but results of studies are still inconclusive. The objective of the current study was to investigate whether day to day variation in salivary testosterone correlates with acne in males. Saliva samples were collected for 120 consecutive days from each of the 40 males. Salivary testosterone concentrations were measured by enzyme-linked immunosorbent assay (ELISA). Facial acne lesions were assessed on a daily basis by photography by the participating males. Potential confounders’ (sexual intercourse, masturbation, physical exercise and disease) were also registered every day by the participants. A significant but weak association between salivary testosterone and acne was found (n = 4602, r = 0.031, P = 0.034). Elevated testosterone concentrations were associated with an increase in acne, but when testosterone concentrations were above twice the individual average, acne lesions paradoxically decreased. The current results indicate that daily fluctuations in salivary testosterone levels in males are associated with acne patterns, but the weak correlation suggests that the effect is too small to be of clinical significance. The analysis in the current study was complicated by a large number of days on which the participants had no acne, as well as the seemingly non-monotonic relation between testosterone and acne. This may indicate that the actual relation is stronger than concluded here.

scholarly journals Study of glycolic acid and salicylic acid peels as a sole therapy in treatment of acne vulgaris

2016 ◽  
Vol 4 (12) ◽  
pp. 2205-2210 ◽  
Author(s):  
Dr. Parikshit Sharma ◽  
◽  
Dr. Akhil Shah ◽  
Dr. Alamjit singh Dhillon ◽  
◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Glycolic Acid ◽  
Acne Vulgaris

scholarly journals Efficacy and Safety of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild-to-Moderate Acne Vulgaris: A Comparative Study

2021 ◽  
pp. 2021063
Author(s):  
Surabhi Dayal ◽  
Satbir Singh ◽  
Priyadarshini Sahu
Keyword(s):  
Salicylic Acid ◽  
Adverse Effects ◽  
Comparative Study ◽  
Clinical Efficacy ◽  
Trichloroacetic Acid ◽  
Acne Vulgaris ◽  
Efficacy And Safety ◽  
Inflammatory Lesions ◽  
Treatment Groups ◽  
Proven Efficacy

Background: Both salicylic acid (SA) and trichloroacetic acid (TCA) have proven efficacy with goodsafety profiles in the treatment of acne vulgaris. Objectives: This study compared the clinical efficacy and safety of 25% TCA and 30% SA peels in thetreatment of mild and moderate acne vulgaris. Methods: Patients with mild or moderate acne vulgaris were randomized into 2 groups of 25 personseach, and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks. Evaluationof active acne was done by individual lesion counts (comedones, papules and pustules) and calculationof the Michaelsson acne score (MAS). Results: Both peels led to significant decrease in individual lesion counts and MAS compared to baselinevalues, without significant differences between the treatment groups. Thus, the peels had equivalentefficacy against acne vulgaris. The TCA peel was better in treating non-inflammatory lesions,while the SA peel was better for inflammatory lesions, but the differences were not significant. Noserious adverse effects were recorded, but more patients in the TCA peel group experienced burningand stinging sensations. Conclusion: The efficacy of 25% TCA is comparable to that of 30% SA in mild-to-moderate acnevulgaris, but safety and tolerability were better with the SA peel than TCA peel.

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