Advanced Virgo is an interferometer for the detection of gravitational waves at the European Gravitational Observatory in Italy. Along with the two Advanced LIGO interferometers in the US, Advanced Virgo is being used to collect data from astrophysical sources such as compact binary coalescences and is currently running the third observational period, collecting gravitational wave event candidates at a rate of more than once per week. Data from the interferometer are processed by running search pipelines for several expected signals, from coalescing compact binaries to continuous waves and burst events. Furthermore, detector characterisation studies are run. Some of the processing needs to be done with low latency, to be able to provide triggers for other observatories and make multi-messenger observations possible. Deep searches are run offline on external computing centres. Thus, data needs also to be reliably and promptly distributed from the EGO site to computer centres in Europe and the US for further analysis and archival storage. Two of the defining characteristics of Virgo computing are the heterogeneity of the activities and the need to interoperate with LIGO. A very wide array of analysis pipelines differing in scientific target, implementation details and running environment assumptions have to be allowed to run ubiquitously and uniformly on dedicated resources and, in perspective, on heterogeneous infrastructures. The current status, possible strategies and outlook of Virgo computing are discussed.
IMPACT OF GLOBALIZATION UNDER THE ICH GUIDELINES ON THE CONDUCT OF REPRODUCTIVE TOXICITY STUDIES-REPORT ON CURRENT STATUS IN JAPAN, EUROPE AND THE US BY QUESTIONNAIRE SURVEY