scholarly journals GABA immunoreactivity in auditory and song control brain areas of zebra finches

2007 ◽  
Vol 34 (1-2) ◽  
pp. 1-21 ◽  
Author(s):  
Raphael Pinaud ◽  
Claudio V. Mello
Keyword(s):  
Zebra Finches ◽  
Brain Areas ◽  
Control Brain ◽  
Song Control

scholarly journals Experimental exposure to urban and pink noise affects brain development and song learning in zebra finches (Taenopygia guttata)

PeerJ ◽  
2016 ◽  
Vol 4 ◽  
pp. e2287 ◽  
Author(s):  
Dominique A. Potvin ◽  
Michael T. Curcio ◽  
John P. Swaddle ◽  
Scott A. MacDougall-Shackleton
Keyword(s):  
Brain Regions ◽  
Urban Environments ◽  
Song Learning ◽  
Zebra Finches ◽  
Pink Noise ◽  
Urban Noise ◽  
Control Brain ◽  
Baseline Corticosterone ◽  
Generational Changes ◽  
Song Control

Recently, numerous studies have observed changes in bird vocalizations—especially song—in urban habitats. These changes are often interpreted as adaptive, since they increase the active space of the signal in its environment. However, the proximate mechanisms driving cross-generational changes in song are still unknown. We performed a captive experiment to identify whether noise experienced during development affects song learning and the development of song-control brain regions. Zebra finches (Taeniopygia guttata) were bred while exposed, or not exposed, to recorded traffic urban noise (Study 1) or pink noise (Study 2). We recorded the songs of male offspring and compared these to fathers’ songs. We also measured baseline corticosterone and measured the size of song-control brain regions when the males reached adulthood (Study 1 only). While male zebra finches tended to copy syllables accurately from tutors regardless of noise environment, syntax (the ordering of syllables within songs) was incorrectly copied affected by juveniles exposed to noise. Noise did not affect baseline corticosterone, but did affect the size of brain regions associated with song learning: these regions were smaller in males that had been had been exposed to recorded traffic urban noise in early development. These findings provide a possible mechanism by which noise affects behaviour, leading to potential population differences between wild animals occupying noisier urban environments compared with those in quieter habitats.

scholarly journals Stoichiometric Analysis of Shifting in Subcellular Compartmentalization of HSP70 within Ischemic Penumbra

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3578
Author(s):  
Federica Mastroiacovo ◽  
Francesca Biagioni ◽  
Paola Lenzi ◽  
Larisa Ryskalin ◽  
Stefano Puglisi-Allegra ◽  
...  
Keyword(s):  
Direct Evidence ◽  
Neuronal Survival ◽  
Hsp 70 ◽  
Preclinical Models ◽  
Brain Areas ◽  
Cell Compartments ◽  
Control Brain ◽  
Disease Modifier ◽  
Subcellular Compartmentalization

The heat shock protein (HSP) 70 is considered the main hallmark in preclinical studies to stain the peri-infarct region defined area penumbra in preclinical models of brain ischemia. This protein is also considered as a potential disease modifier, which may improve the outcome of ischemic damage. In fact, the molecule HSP70 acts as a chaperonine being able to impact at several level the homeostasis of neurons. Despite being used routinely to stain area penumbra in light microscopy, the subcellular placement of this protein within area penumbra neurons, to our knowledge, remains undefined. This is key mostly when considering studies aimed at deciphering the functional role of this protein as a determinant of neuronal survival. The general subcellular placement of HSP70 was grossly reported in studies using confocal microscopy, although no direct visualization of this molecule at electron microscopy was carried out. The present study aims to provide a direct evidence of HSP70 within various subcellular compartments. In detail, by using ultrastructural morphometry to quantify HSP70 stoichiometrically detected by immuno-gold within specific organelles we could compare the compartmentalization of the molecule within area penumbra compared with control brain areas. The study indicates that two cell compartments in control conditions own a high density of HSP70, cytosolic vacuoles and mitochondria. In these organelles, HSP70 is present in amount exceeding several-fold the presence in the cytosol. Remarkably, within area penumbra a loss of such a specific polarization is documented. This leads to the depletion of HSP70 from mitochondria and mostly cell vacuoles. Such an effect is expected to lead to significant variations in the ability of HSP70 to exert its physiological roles. The present findings, beyond defining the neuronal compartmentalization of HSP70 within area penumbra may lead to a better comprehension of its beneficial/detrimental role in promoting neuronal survival.

scholarly journals Neurotensin and neurotensin receptor 1 mRNA expression in song-control regions changes during development in male zebra finches

2018 ◽  
Vol 78 (7) ◽  
pp. 671-686
Author(s):  
Devin P. Merullo ◽  
Chinweike N. Asogwa ◽  
Miguel Sanchez-Valpuesta ◽  
Shin Hayase ◽  
Bikash R. Pattnaik ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Zebra Finches ◽  
Neurotensin Receptor ◽  
Song Control ◽  
Neurotensin Receptor 1 ◽  
Control Regions

scholarly journals The expression of delta opioid receptor mRNA in adult male zebra finches (Taenopygia guttata)

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256599
Author(s):  
Pooja Parishar ◽  
Neha Sehgal ◽  
Soumya Iyengar
Keyword(s):  
Opioid Receptors ◽  
Sequence Similarity ◽  
Expression Patterns ◽  
Auditory Pathway ◽  
Zebra Finches ◽  
Endogenous Opioid System ◽  
Endogenous Opioid ◽  
High Sequence Similarity ◽  
Brain Functions ◽  
Song Control

The endogenous opioid system is evolutionarily conserved across reptiles, birds and mammals and is known to modulate varied brain functions such as learning, memory, cognition and reward. To date, most of the behavioral and anatomical studies in songbirds have mainly focused on μ-opioid receptors (ORs). Expression patterns of δ-ORs in zebra finches, a well-studied species of songbird have not yet been reported, possibly due to the high sequence similarity amongst different opioid receptors. In the present study, a specific riboprobe against the δ-OR mRNA was used to perform fluorescence in situ hybridization (FISH) on sections from the male zebra finch brain. We found that δ-OR mRNA was expressed in different parts of the pallium, basal ganglia, cerebellum and the hippocampus. Amongst the song control and auditory nuclei, HVC (abbreviation used as a formal name) and NIf (nucleus interfacialis nidopallii) strongly express δ-OR mRNA and stand out from the surrounding nidopallium. Whereas the expression of δ-OR mRNA is moderate in LMAN (lateral magnocellular nucleus of the anterior nidopallium), it is low in the MSt (medial striatum), Area X, DLM (dorsolateral nucleus of the medial thalamus), RA (robust nucleus of the arcopallium) of the song control circuit and Field L, Ov (nucleus ovoidalis) and MLd (nucleus mesencephalicus lateralis, pars dorsalis) of the auditory pathway. Our results suggest that δ-ORs may be involved in modulating singing, song learning as well as spatial learning in zebra finches.

Nerve growth factor effects on the song control system of zebra finches

1997 ◽  
Vol 223 (3) ◽  
pp. 161-164 ◽  
Author(s):  
M Fiore ◽  
S.N Patel ◽  
E Alleva ◽  
L Aloe ◽  
N.S Clayton
Keyword(s):  
Control System ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Zebra Finches ◽  
Nerve Growth ◽  
Song Control System ◽  
Song Control

scholarly journals Early nutritional stress impairs development of a song-control brain region in both male and female juvenile song sparrows ( Melospiza melodia ) at the onset of song learning

2006 ◽  
Vol 273 (1600) ◽  
pp. 2559-2564 ◽  
Author(s):  
Ian F MacDonald ◽  
Bethany Kempster ◽  
Liana Zanette ◽  
Scott A MacDougall-Shackleton
Keyword(s):  
Food Restriction ◽  
Rapid Development ◽  
Nutritional Stress ◽  
Brain Regions ◽  
Song Learning ◽  
Melospiza Melodia ◽  
Developmental Stress ◽  
Song Sparrows ◽  
Control Brain ◽  
Song Control

Birdsong is a sexually selected trait and is often viewed as an indicator of male quality. The developmental stress hypothesis proposes a model by which song could be an indicator; the time during early development, when birds learn complex songs and/or local variants of song, is of rapid development and nutritional stress. Birds that cope best with this stress may better learn to produce the most effective songs. The developmental stress hypothesis predicts that early food restriction should impair development of song-control brain regions at the onset of song learning. We examined the effect of food restriction on song-control brain regions in fledgling (both sexes, 23–26 days old) song sparrows ( Melospiza melodia ). Food restriction selectively reduced HVC volume in both sexes. In addition, sex differences were evident in all three song-control regions. This study lends further support to a growing body of literature documenting a variety of behavioural, physiological and neural detriments in several songbird species resulting from early developmental stress.

scholarly journals Learning to breathe and sing: development of respiratory-vocal coordination in young songbirds

2011 ◽  
Vol 106 (4) ◽  
pp. 1747-1765 ◽  
Author(s):  
Lena Veit ◽  
Dmitriy Aronov ◽  
Michale S. Fee
Keyword(s):  
Developmental Changes ◽  
Respiratory Pattern ◽  
Zebra Finches ◽  
Vocal Production ◽  
Song Control Nuclei ◽  
Before And After ◽  
Proper Name ◽  
Song Control ◽  
Striking Contrast

How do animals with learned vocalizations coordinate vocal production with respiration? Songbirds such as the zebra finch learn their songs, beginning with highly variable babbling vocalizations known as subsong. After several weeks of practice, zebra finches are able to produce a precisely timed pattern of syllables and silences, precisely coordinated with expiratory and inspiratory pulses (Franz M, Goller F. J Neurobiol 51: 129–141, 2002). While respiration in adult song is well described, relatively little is known about respiratory patterns in subsong or about the processes by which respiratory and vocal patterns become coordinated. To address these questions, we recorded thoracic air sac pressure in juvenile zebra finches prior to the appearance of any consistent temporal or acoustic structure in their songs. We found that subsong contains brief inspiratory pulses (50 ms) alternating with longer pulses of sustained expiratory pressure (50–500 ms). In striking contrast to adult song, expiratory pulses often contained multiple (0–8) variably timed syllables separated by expiratory gaps and were only partially vocalized. During development, expiratory pulses became shorter and more stereotyped in duration with shorter and fewer nonvocalized parts. These developmental changes eventually resulted in the production of a single syllable per expiratory pulse and a single inspiratory pulse filling each gap, forming a coordinated sequence similar to that of adult song. To examine the role of forebrain song-control nuclei in the development of respiratory patterns, we performed pressure recordings before and after lesions of nucleus HVC (proper name) and found that this manipulation reverses the developmental trends in measures of the respiratory pattern.

Sign in / Sign up

Export Citation Format

Share Document