In the present study, bubble-particle interactions in suspensions are investigated by a coupled immersed-boundary and volume-of-fluid method (IB-VOF method), which is proposed by the present authors. The validity of the numerical method is examined through simulations of a rising bubble in a liquid and a falling particle in a liquid. Dilute particle-laden flows and a gas-liquid-solid flow involving solid particles and bubbles of comparable sizes to one another (Db/Dp = 1) are simulated. Drag coefficients of particles in particle-laden flows are estimated and flow fields involving multiple particles and a bubble are demonstrated.