Human Papillomavirus (HPV): unawareness of causal role HPV infection in cervical cancer, HPV vaccine availability and HPV vaccine uptake among female schoolteachers in a Middle Eastern country

Background The human papillomavirus (hpv) is a common sexually transmitted infection and a primary cause of cervical cancer. The Government of Canada has set a target of reaching 90% hpv vaccine coverage among adolescents by 2025. Here, we examine hpv vaccine uptake in school-based immunization programs across Canada and explore how achieving the 90% target could affect the future incidence of cervical cancer, mortality, and health system expenditures in a cohort of Canadian women.Methods Data for hpv vaccine uptake in the most recent reported school year available in each jurisdiction were provided in 2017 by jurisdictional school-based immunization programs and were used to estimate a national weighted average of 67%. The OncoSim microsimulation model (version 2.5) was used to compare 3 different levels of hpv vaccine uptake (0%, 67%, 90%) on health and economic outcomes for a hypothetical cohort of all 5- to 10-yearold girls in Canada in 2015.Results Vaccine uptake for girls in school-based programs varied from 55.0% to 92.0% in the jurisdictions reviewed. The OncoSim model projects that increasing uptake to 90% from 67% would result in a 23% reduction in cervical cancer incidence rates (to 3.1 cases from 4.0 cases per 100,000, averaged across the lifetime of the cohort) and a 23% decline in the average annual mortality rate (to 1.0 deaths from 1.3 deaths per 100,000). Finally, the model projects that the health system will incur a cost of $9 million (1% increase) during the lifetime of the cohort if uptake is increased to 90% from 67%. Costs are discounted (1.5%) and expressed in 2016 Canadian dollars. Costs reflect the payer perspective.Conclusions Our model shows that increasing hpv vaccine uptake to 90% from current levels for girls in schoolbased immunization programs could result in substantial reductions in the future incidence and mortality rates for cervical cancer in Canada.

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Human Papillomavirus Awareness, Vaccine Status, and Risk Factors in Female Emergency Patients

Western Journal of Emergency Medicine ◽

10.5811/westjem.2019.12.44422 ◽

2020 ◽

Vol 21 (2) ◽

pp. 203-208

Author(s):

Lauren Walter ◽

Elizabeth Leader ◽

James Galbraith

Keyword(s):

Risk Factors ◽

Cervical Cancer ◽

Human Papillomavirus ◽

High Risk ◽

Cancer Risk ◽

Hpv Vaccine ◽

Vaccine Uptake ◽

Cancer Risk Factors ◽

Cervical Cancer Risk ◽

Hpv Vaccine Uptake

Introduction: A vaccine targeting high-risk human papillomavirus (HPV) strains can effectively prevent HPV-associated cervical cancer risk. However, many girls and women do not receive the vaccine, more often those impacted by health disparities associated with race and/or socioeconomic status. This same disparate population has also been shown to be at higher risk for cervical cancer. Many of these women also rely on the emergency department (ED) as a safety net for their healthcare. This study sought to gather information pertaining to HPV and cervical cancer risk factors, awareness of HPV and the vaccine, as well as HPV vaccine uptake in female patients presenting to an ED. Methods: We obtained 81 surveys completed by female ED patients. Demographics included age, race, income, insurance status, primary care provider status, and known cervical-cancer risk factors. Subsequent survey questions explored respondents’ knowledge, familiarity, and attitudes regarding HPV, cervical cancer, and the HPV vaccine, including vaccination uptake rates. We analyzed data using descriptive statistics and Fisher’s exact test. Results: Approximately one in seven respondents (14.8%) had never previously heard of HPV and 32.1% were unaware of the existence of a HPV vaccine. Minority patients, including those who were Black and Hispanic patients, low income patients, and uninsured and publicly insured patients were less likely to be aware of HPV and the vaccine and likewise were less likely to be offered and receive the vaccine. More than 60% of all respondents (61.3%) had never previously been offered the vaccine, and only 24.7% of all respondents had completed the vaccine series. Conclusion: Female ED patients may represent an at-risk cohort with relatively low HPV awareness and low HPV vaccine uptake. The ED could represent a novel opportunity to access and engage high-risk HPV populations.

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Beliefs and Knowledge Related to Human Papillomavirus (HPV) Vaccine among African Americans and African Immigrants Young Adults

10.21203/rs.3.rs-1087078/v1 ◽

2021 ◽

Author(s):

Adebola Adegboyega ◽

Omoadoni Obielodan ◽

Amanda Wiggins ◽

Mark Dignan ◽

Lovoria B. Williams

Keyword(s):

Young Adults ◽

Human Papillomavirus ◽

Focus Group ◽

Hpv Vaccine ◽

Hpv Vaccination ◽

African Immigrants ◽

Hpv Infection ◽

Vaccine Uptake ◽

Hpv Knowledge ◽

Hpv Vaccine Uptake

Abstract Background: Despite the disparate Human papillomavirus (HPV) infection rates among sexually active black young adults, HPV vaccine uptake remains low among this population. This study aimed to explore HPV beliefs, attitudes, and knowledge among black young adults and provide recommendations on ways to improve vaccine uptake.Methods: We used a mixed-method, convergent design to conduct five focus groups and administered a 40-item electronic survey that was developed with Health Belief Model (HBM) constructs. We assessed HPV and vaccine knowledge, barriers, and attitudes toward vaccination. We analyzed quantitative data using descriptive statistics and bivariate methods. Focus group transcripts were analyzed using content analysis. Results were integrated to obtain a better understanding of the topic.Results: Forty individuals participated in the study. The mean age was 22.2±4.5 years and 55% identified as African immigrants. Integrated data revealed themes mapped to relevant HBM constructs. Almost one third (32.5%) of participants were unaware of their susceptibility to HPV infection and its severity. From focus group discussions, the majority (75%) believed that vaccines are beneficial. Major cues to action include promoting HPV vaccine uptake via community wide informational sessions, provider recommendation, and social and mass media campaigns. Conclusion: Barriers to vaccine uptake, limited HPV knowledge, and lack of vaccine recommendation are important factors contributing to low vaccine uptake among black young adults. Interventions to decrease barriers to HPV vaccination, increase HPV knowledge, address misconceptions, and unfavorable beliefs are needed to promote to promote HPV vaccine uptake.

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Knowledge of Human Papillomavirus and Uptake of its Vaccine among Female Undergraduate Students of Ambrose Alli University, Ekpoma, Nigeria

Journal of Community Medicine and Primary Health Care ◽

10.4314/jcmphc.v33i1.6 ◽

2021 ◽

Vol 33 (1) ◽

pp. 64-75

Author(s):

A.R. Isara ◽

N. Osayi

Keyword(s):

Cervical Cancer ◽

Human Papillomavirus ◽

Undergraduate Students ◽

Hpv Vaccine ◽

Sexual Debut ◽

Statistical Significance ◽

Hpv Infection ◽

Vaccine Uptake ◽

P Value ◽

Female Undergraduate

Background: Human Papillomavirus (HPV) is a prerequisite for the development of cervical cancer which is the fourth most common cancer affecting women worldwide. The use of HPV vaccine has been found to be responsible for significant decline in the prevalence of HPV infection and consequently, of cervical cancer. This study assessed the knowledge of HPV and the uptake of HPV vaccine among female undergraduate students of Ambrose Alli University, Ekpoma, Nigeria.Methods: This institution-based cross-sectional study was carried out among 229 students selected using multi-staged sampling technique. A structured, pretested, self-administered questionnaire was used to collect data. IBM SPSS version 21.0 was used for data analysis. Statistical significance was set at p-value less than 0.05.Results: Only 12 (5.2%) students were knowledgeable about HPV and 39 (17.0%) were aware of the existence of HPV vaccines. The participants’ age (p = 0.031) and level of study (p = 0.026) were significantly associated with knowledge of HPV. Only 1 (0.44%) student had received the vaccine. Eight (10.8%) students had their sexual debut at 10 to 14 years, 9 (12.1%) had more than five sexual partners and 21 (23.4%) never used condom during sexual intercourse.Conclusion: The knowledge about HPV infection and uptake of HPV vaccine were very low in this study. Concerted effort should be made by health authorities to create awareness about HPV infection and its vaccine among university students. This will improve HPV vaccine uptake, prevent HPV infections and reduce the prevalence of cervical cancer.

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Attitudes, Knowledge and Factors Associated with Human Papillomavirus (HPV) Vaccine Uptake in Adolescent Girls and Young Women in Victoria, Australia

PLoS ONE ◽

10.1371/journal.pone.0161846 ◽

2016 ◽

Vol 11 (8) ◽

pp. e0161846 ◽

Cited By ~ 24

Author(s):

Iris L. Y. Tung ◽

Dorothy A. Machalek ◽

Suzanne M. Garland

Keyword(s):

Human Papillomavirus ◽

Adolescent Girls ◽

Young Women ◽

Hpv Vaccine ◽

Vaccine Uptake ◽

Factors Associated ◽

Hpv Vaccine Uptake

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Predictors of Human Papillomavirus Vaccine uptake or intent among parents of preadolescents and adolescents

Journal of Nursing Education and Practice ◽

10.5430/jnep.v7n6p35 ◽

2017 ◽

Vol 7 (6) ◽

pp. 35 ◽

Cited By ~ 2

Author(s):

Kimberlee Dayal ◽

Sarah Robinson ◽

Jessica Schoening ◽

Mary Catherine Smith ◽

Son Chae Kim

Keyword(s):

Human Papillomavirus ◽

Hpv Vaccine ◽

Parental Education ◽

Hpv Vaccination ◽

College Education ◽

Vaccine Effectiveness ◽

Vaccine Uptake ◽

Human Papillomavirus Vaccine ◽

Hpv Knowledge ◽

Hpv Vaccine Uptake

Aim: The aim of this study was to examine predictors of human papillomavirus (HPV) vaccine uptake or intent among parents of pre-adolescents and adolescents.Methods: A cross-sectional descriptive study was conducted among parents of girls aged 9 to 18 years, visiting two primary care clinics in central Texas from September to November 2015. Pearson’s product-moment correlation procedures and path analyses based on Health Belief Model were performed.Results: Path analysis showed that provider recommendation for HPV vaccination (β = 0.37; p < .001) and perceived HPV vaccine harm (β = -0.48; p < .001) had statistically significant direct effects on HPV vaccine uptake or intent. The perceived HPV vaccine effectiveness was directly influenced by HPV knowledge (β = 0.39; p < .001), empowerment in parent-provider relationships (β = 0.30; p = .006) and parental college education (β = 0.23; p = .039).}Conclusions: Together with parental empowerment fostering an equal partnership with providers, targeted education to improve parental HPV knowledge may convince them of the HPV vaccine effectiveness. This, in turn, may help them put the perceived HPV vaccine harm in proper perspective and allow them to make informed decisions regarding the timely HPV vaccination of their children. Because provider recommendation is one of the most important contributing factors for HPV vaccine uptake or intent, parental education and recommendations from nurses will help reduce the knowledge gaps and empower parents to make the timely decisions to vaccinate their children.

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Human Papillomavirus (HPV) Vaccine Uptake and the Willingness to Receive the HPV Vaccination among Female College Students in China: A Multicenter Study

Vaccines ◽

10.3390/vaccines8010031 ◽

2020 ◽

Vol 8 (1) ◽

pp. 31 ◽

Cited By ~ 2

Author(s):

Dingyun You ◽

Liyuan Han ◽

Lian Li ◽

Jingcen Hu ◽

Gregory D. Zimet ◽

...

Keyword(s):

College Students ◽

Human Papillomavirus ◽

Hpv Vaccine ◽

Hpv Vaccination ◽

Geographical Region ◽

Vaccine Uptake ◽

Female College Students ◽

Female College ◽

To Receive ◽

Hpv Vaccine Uptake

Background: This study aimed to determine human papillomavirus (HPV) vaccine uptake and willingness to receive HPV vaccination among female college students, in China, and its associated factors. Methods: An online cross-sectional survey of female college students across the eastern, central, and western regions of China was undertaken between April and September 2019. Partial least squares structural equation modeling (PLS-SEM) was used to examine factors associated with the HPV vaccine uptake and willingness to receive the HPV vaccine. Results: Among the total 4220 students who participated in this study, 11.0% reported having been vaccinated against HPV. There are direct effects of indicators of higher socioeconomic status, older age (β = 0.084 and p = 0.006), and geographical region (residing in Eastern China, β = 0.033, and p = 0.024) on HPV vaccine uptake. Higher knowledge (β = 0.062 and p < 0.000) and perceived susceptibility (β = 0.043 and p = 0.002) were also predictors of HPV vaccine uptake. Of those who had not received the HPV vaccine, 53.5% expressed a willingness to do so. Likewise, social economic status indicators were associated with the willingness to receive the HPV vaccine. Total knowledge score (β = 0.138 and p < 0.001), both perceived susceptibility (β = 0.092 and p < 0.001) and perceived benefit (β = 0.088 and p < 0.001), and sexual experience (β = 0.041 and p = 0.007) had a positive and significant direct effect on the willingness to receive the HPV vaccine, while perceived barriers (β = −0.071 and p < 0.001) had a negative effect on the willingness to receive the HPV vaccine. Conclusions: Geographical region and socioeconomic disparities in the HPV vaccination uptake rate and willingness to receive the HPV vaccine provide valuable information for public health planning that aims to improve vaccination rates in underserved areas in China. The influence of knowledge and perceptions of HPV vaccination suggests the importance of communication for HPV immunization.

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