Heat transfer of PEGylated cobalt ferrite nanofluids for magnetic fluid hyperthermia therapy: In vitro cellular study

Hyperthermia therapy for cancer has attracted much attention nowadays. The study on the heat transfer in the magnetic fluid and the tumor is crucial for the successful application of magnetic fluid hyperthermia (MFH). Water-based Fe3O4 magnetic fluid is expected to be a most appropriate candidate for MFH due to the good biocompatibility, high saturation magnetization, super-paramagnetization and high chemical stability. In this paper, we explore the heat generation and transfer in magnetic fluid which is placed under an AC magnetic field. It is found that the amplitude and the frequency of alternating magnetic field, particle size and volume fraction have a pronounce influence on maximum temperature of hyperthermia.

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Preliminary in-vitro investigation of magnetic fluid hyperthermia in cervical cancer cells

Journal of Magnetism and Magnetic Materials ◽

10.1016/j.jmmm.2019.166057 ◽

2020 ◽

Vol 497 ◽

pp. 166057 ◽

Cited By ~ 4

Author(s):

Kinnari Parekh ◽

Anand Bhardwaj ◽

Neeraj Jain

Keyword(s):

Cervical Cancer ◽

Cancer Cells ◽

Magnetic Fluid ◽

Magnetic Fluid Hyperthermia ◽

In Vitro Investigation ◽

Cervical Cancer Cells

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Study of structural and magnetic properties and heat induction of gadolinium-substituted manganese zinc ferrite nanoparticles for in vitro magnetic fluid hyperthermia

Journal of Colloid and Interface Science ◽

10.1016/j.jcis.2019.01.063 ◽

2019 ◽

Vol 541 ◽

pp. 192-203 ◽

Cited By ~ 8

Author(s):

S.V. Jadhav ◽

P.S. Shewale ◽

B.C. Shin ◽

M.P. Patil ◽

G.D. Kim ◽

...

Keyword(s):

Magnetic Properties ◽

Magnetic Fluid ◽

Zinc Ferrite ◽

Ferrite Nanoparticles ◽

Magnetic Fluid Hyperthermia ◽

Heat Induction ◽

Manganese Zinc ◽

Manganese Zinc Ferrite ◽

Structural And Magnetic Properties

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On the relaxation time of interacting superparamagnetic nanoparticles and implications for magnetic fluid hyperthermia

Beilstein Journal of Nanotechnology ◽

10.3762/bjnano.10.127 ◽

2019 ◽

Vol 10 ◽

pp. 1280-1289 ◽

Cited By ~ 3

Author(s):

Andrei Kuncser ◽

Nicusor Iacob ◽

Victor E Kuncser

Keyword(s):

Relaxation Time ◽

Magnetic Fluid ◽

Critical Discussion ◽

Superparamagnetic Nanoparticles ◽

Perturbation Approach ◽

Interparticle Interactions ◽

Micromagnetic Simulations ◽

Magnetic Fluid Hyperthermia ◽

Theoretical Support ◽

Hyperthermia Therapy

A critical discussion on the presently available models for the relaxation time of magnetic nanoparticles approaching the superparamagnetic regime in the presence of interparticle dipolar interactions is considered. The direct implications of such interactions for magnetic fluid hyperthermia therapy through susceptibility loss mechanisms give rise to an indirect method for their study via specific absorption rate measurements performed on ferrofluids of different volume fractions. The theoretical support for the specific evolution of the relaxation time constant and the anisotropy energy barrier versus the interparticle interactions in a perturbation approach of the simple Néel expression for the relaxation time is provided via static and time-dependent micromagnetic simulations.

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