On the in Vitro Hyperthermia of Magnetic Fluid in AC Magnetic Field

Hyperthermia therapy for cancer has attracted much attention nowadays. The study on the heat transfer in the magnetic fluid and the tumor is crucial for the successful application of magnetic fluid hyperthermia (MFH). Water-based Fe3O4 magnetic fluid is expected to be a most appropriate candidate for MFH due to the good biocompatibility, high saturation magnetization, super-paramagnetization and high chemical stability. In this paper, we explore the heat generation and transfer in magnetic fluid which is placed under an AC magnetic field. It is found that the amplitude and the frequency of alternating magnetic field, particle size and volume fraction have a pronounce influence on maximum temperature of hyperthermia.

Modeling Heat and Mass Transfer Correlations for Flow Through Micro Channels in Monolith Honeycomb Catalytic Combustor

This paper investigated performance characteristics analysis of catalytic combustion by utilizing 1-D models incorporated heat and mass transfer correlations. The 1-D numerical results were compared with 2-D models studies and experimental data. The performance characteristics were mainly the effects of operating conditions on methane conversion rate. The comparable analysis confirmed that 1-D model can success in predicting performance of catalytic combustion when empiric inter-phase heat and mass transfer correlations are used and appropriate operating conditions are chosen.

Marangoni Flow-Induced Droplet Deformation for Micromirror Applications

A simple method that utilizes Marangoni flow to create droplet deformation and to tilt micro-objects is presented. Contact angle hysteresis is employed to prevent the droplet from rolling away from the position. The device consists of a micromirror placed on the droplet, and can produce a 6.5° tilting angle when actuated at 30 V. It also demonstrates its scanning capability and potential as a micromirror.

Convection Heat Transfer of CO2 at Supercritical Pressures in a Vertical Mini Tube

This paper presents the experimental and numerical investigation results of the convection heat transfer of CO2 at supercritical pressures in a 0.0992 mm diameter vertical tube at various inlet Reynolds numbers, heat fluxes and flow directions. The effects of buoyancy and flow acceleration resulted from the dramatic properties variation were investigated. Results showed that the local wall temperature varied non-linearly for both upward and downward flow when the heat flux was high. The difference of the local wall temperature between upward flow and downward flow was very small when other test conditions were held the same, which indicates that for supercritical CO2 flowing in a mini tube as employed in this study, the buoyancy effect on the convection heat transfer was quite insignificant, and the flow acceleration induced by the axial density variation with temperature was the main factor that lead to the abnormal local wall temperature distribution at high heat fluxes. The predicted values using the LB low Reynolds number turbulence model correspond well with the measured data. Velocity profiles and turbulence kinetic energy near the wall varying along the tube generated by the numerical simulations were presented to develop a better understanding.

Anomalous Heat Conduction, Diffusion and Heat Rectification in Nanoscale Structures

In this paper, we report the recent developments in the study of heat transport in nano materials. First of all, we show that phonon transports in nanotube super-diffusively which leads to a length dependence thermal conductivity, thus breaks down the Fourier law. Then we discuss how the introduction of isotope doping can reduce the thermal conductivity efficiently. The theoretical results are in good agreement with experimental ones. Finally, we will demonstrate that nanoscale structures are promising candidates for heat rectification.

Second Order Slip Flow Effects on Heat Transfer Performance of Microchannels

First and second order slip flow models in rectangular microchannels heated at constant and uniform wall temperature are studied. The velocity and temperature profiles for hydrodynamically and thermally developed incompressible slip flow regime available in literature are used. The average nondimensional slip velocity and temperature jump are found by using first and second order slip flow models. The average Nusselt number is also derived by using both first and second order slip flow models. The effects of Knudsen number, aspect ratio and second order slip flow model on the heat transfer characteristics of microchannel are explored.

Numerical Research of Roughness Effects on Flow and Heat Transfer Characteristics in Flat Microchannels

Roughness effects on flow and heat transfer in flat microchannels has been numerically simulated by using CFD with fluid-solid conjugate heat transfer techniques, the surface roughness has been modeled through a series triangular toothed roughness cells. In this paper, the influence for roughness on the entrance length of flow and heat transfer has been emphasized, the influence for relative roughness on transitional Reynolds number has been also analyzed at the same time.

Measurement of Water-Cryoprotectant Mutual Diffusivity in Micro-Scale Biological Tissues at Subzero Temperatures

Water-cryoprotectant mutual diffusivity (D¯) in biological tissues at subzero temperatures is of critical importance for optimizing tissue or organ cryopreservation procedures. Currently, there exist no attempts to measure D¯ at subzero temperatures. We pioneered a thermal analytic method to measure this mass transfer parameter in biological tissues at the level of micro-liters. Using differential scanning calorimetry, the values of D¯ in mouse ovaries (∼4–8μl) with ethylene glycol (EG) as cryoprotectant were measured at −20°C, −10°C, 0°C, 10°C and 20°C. The results show the Arrhenius law is strictly followed (R2 = 0.99) over this temperature range with the activation energy as 3.78 kcal/mol. The value of D¯ with EG as the cryoprotectant at 20°C, 6.2×10−7cm2/s, agrees well with that previously measured using a magnetic resonance imaging method at the same temperature, 6.1×10−7cm2/s.

Experimental Study of Flow and Heat Transfer Characteristics in Silicon-Based Corrugated Microchannels

In this paper, the silicon-based corrugated microchannels used for the heat transfer enhancement were fabricated by MEMS technology for the first time. Both the flow and convective heat transfer characteristics of the deionized water through these corrugated microchannels were investigated experimentally, and comparisons were performed between corrugated microchannels and straight microchannels with the same cross-sectional aspect ratio (height-to-width ratio) and same hydraulic diameter. Experimental results showed that both the flow friction and Nusselt number in corrugated microchannels increased considerably compared with those in straight microchannels, and this increase became enlarged with the increase in the Reynolds number. With the same pumping power, using corrugated microchannels instead of straight microchannels caused the reduction in the total thermal resistance. The heat transfer enhancement mechanism of the corrugated microchannels was discussed. The results presented in this paper help to design the high efficiency integrated chip cooling system.

Development of Silicon Based Heat Spreader for High Power Electronic Devices

This article presents the development of silicon based heat spreader devices, called hexcells. Several key technical aspects, including the hexcell MEMS fabrication process, mechanical strength studies, vacuum sealing technique, and phase change and mass transport visualization, have been developed and studied. The hexcell development prototypes are fabricated by MEMS photolithography and dry-etch processes, with eutectic bonding to form a sealed silicon chamber with openings for charging with the working fluid. Using Ansys as the modeling tool, we optimized the hexcell total mechanical strength by incorporating six interior support posts to reinforce the structure. In terms of the optimized design, experimental results on actual hexcell samples show that a well-bonded hexcell can withstand over 60psi without destructive failure. Vacuum sealing are divided into helium and vapor leakage tests. With metalized and solder-sealed sidewalls, both testing results confirm good vacuum sealing. The wick structure used in the present hexcell is silicon pillars with dimensions of 50μm in diameter and 250μm in height. The pillars are etched before the hexcell is bonded and formed. Experiments using the silicon wick structure demonstrate over 300W/cm2 cooling capacity and visualization shows the intensive phase change on the heating area.