Changes in knee pain, perceived need for surgery, physical function and quality of life after dietary weight loss in obese women diagnosed with knee osteoarthritis

There is an increasing incidence, prevalence, and burden of knee osteoarthritis due to a global increase in obesity and an aging population. The aim of the present study was to compare the effectiveness of the addition of aerobic exercises performed in an unloaded or loaded position to a conventional exercise program in overweight subjects with knee osteoarthritis. Twenty-four subjects were randomly allocated to receive 36 sessions of 30-min duration of either sitting aerobic exercises (experimental group) or standing aerobic exercises (control group). Pain intensity, knee disability, and quality-of-life data were collected at baseline and at 12, 24, and 36 sessions. Generalized linear mixed models (GLMMs) were constructed for the analysis of the differences. Significant differences were found in the experimental group for self-reported pain and knee pain and disability at 24 and 36 sessions (p < 0.05). Significant between-group differences were observed in change in self-reported knee pain and disability and quality of life from baseline to 24th- and 36th-session measurements in favor of the experimental group. Adherence to treatment was higher in the experimental group. Adding aerobic exercises in an unloaded position to a conventional exercise program produced superior effects over time for self-reported knee pain, knee pain and disability and quality of life compared to loaded aerobic exercises in overweight subjects with knee osteoarthritis.

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The Ottawa panel clinical practice guidelines for the management of knee osteoarthritis. Part one: introduction, and mind-body exercise programs

Clinical Rehabilitation ◽

10.1177/0269215517691083 ◽

2017 ◽

Vol 31 (5) ◽

pp. 582-595 ◽

Cited By ~ 29

Author(s):

Lucie Brosseau ◽

Jade Taki ◽

Brigit Desjardins ◽

Odette Thevenot ◽

Marlene Fransen ◽

...

Keyword(s):

Quality Of Life ◽

Pain Relief ◽

Knee Osteoarthritis ◽

Physical Function ◽

Tai Chi ◽

Statistical Significance ◽

Clinical Importance ◽

Exercise Programs ◽

High Quality

Objective: To identify effective mind-body exercise programs and provide clinicians and patients with updated, high-quality recommendations concerning non-traditional land-based exercises for knee osteoarthritis. Methods: A systematic search and adapted selection criteria included comparative controlled trials with mind-body exercise programs for patients with knee osteoarthritis. A panel of experts reached consensus on the recommendations using a Delphi survey. A hierarchical alphabetical grading system (A, B, C+, C, D, D+, D-) was used, based on statistical significance ( P < 0.5) and clinical importance (⩾15% improvement). Results: The four high-quality studies identified demonstrated that various mind-body exercise programs are promising for improving the management of knee osteoarthritis. Hatha Yoga demonstrated significant improvement for pain relief (Grade B) and physical function (Grade C+). Tai Chi Qigong demonstrated significant improvement for quality of life (Grade B), pain relief (Grade C+) and physical function (Grade C+). Sun style Tai Chi gave significant improvement for pain relief (Grade B) and physical function (Grade B). Conclusion: Mind-body exercises are promising approaches to reduce pain, as well as to improve physical function and quality of life for individuals with knee osteoarthritis.

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Socioeconomic inequalities in knee pain, knee osteoarthritis and health-related quality of life: A population-based cohort study

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2016.01.393 ◽

2016 ◽

Vol 24 ◽

pp. S201

Author(s):

A. Ahmad Kiadaliri ◽

M. Gerhardsson de Verdier ◽

A. Turkiewicz ◽

L. Lohmander ◽

M. Englund

Keyword(s):

Quality Of Life ◽

Cohort Study ◽

Knee Osteoarthritis ◽

Knee Pain ◽

Population Based ◽

Socioeconomic Inequalities ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Effects of weight change and physical activity on knee pain and health-related quality of life in East Asian women aged 50 years and older with knee osteoarthritis: a population-based study

10.21203/rs.2.12546/v1 ◽

2019 ◽

Author(s):

Chongbum Chang ◽

Young Choi ◽

Seung-Baik Kang ◽

Chin Youb Chung ◽

Moon Seok Park ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Knee Osteoarthritis ◽

Knee Pain ◽

Weight Change ◽

Population Based ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Abstract Background This study aimed to investigate the effects of weight change and physical activity on the level of knee pain and health-related quality of life in East Asian women with knee osteoarthritis using population-based data. Methods A total of 564 women (mean age, 68.2 years, standard deviation, 8.9 years) aged 50 years or older with knee osteoarthritis (Kellgren-Lawrence grade ≥2) were included in the data analyses from the fifth Korea National Health and Nutrition Examination Survey. Data regarding the radiographic grade, weight change during the past year, physical activity, level of knee pain, and health-related quality of life (EuroQOL five-dimension [EQ-5D] index) were collected. Multiple regression analysis was performed to identify factors significantly affecting the level of knee pain and health-related quality of life in subgroups according to the body mass index (BMI) range (≤22.5, between 22.6 and 27.5, and >27.5 kg/m2). Result In women with 22.5 kg/m227.5 kg/m2, weekly hours of moderate-intensity activity showed significant negative correlation with EQ-5D. Conclusions The effects of weight change and physical activity on knee pain and health-related quality of life could be different according to BMI ranges. Well-designed interventions to improve both knee pain and health-related quality of life need to be investigated in future studies that would assess physical activity, diet, and weight changes.

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Neuropathic pain in knee osteoarthritis

Advances in Rheumatology ◽

10.1186/s42358-021-00225-0 ◽

2021 ◽

Vol 61 (1) ◽

Author(s):

Uğur Güngör Demir ◽

Ali Nail Demir ◽

Naciye Füsun Toraman

Keyword(s):

Quality Of Life ◽

Body Composition ◽

Neuropathic Pain ◽

Knee Osteoarthritis ◽

Physical Function ◽

Body Mass ◽

Symptom Duration ◽

Group 2 ◽

Group 1

Abstract Background This study aimed to investigate the relationship between the neuropathic pain in knee osteoarthritis with the body composition, anthropometric and postural features, physical function, and quality of life. Methods Patients with primary knee osteoarthritis, 50–70 years of age, were included in the study and divided into Group 1 with neuropathic pain and Group 2 with no neuropathic pain according to Douleur Neuropathique-4. The groups were compared in terms of demographic, clinical, radiological, laboratory findings and anthropometric measurements, body composition, physical function tests, osteoarthritis severity, quality of life, and posturography. Results 200 patients were included in the study. 98 (82.6% female) were in Group 1 and 102 (74.5% female) in Group 2. Age was higher in Group 1 compared to Group 2 [61 (50–70) and 57.5 (50–70), respectively, p = 0.03]. Symptom duration was also longer in Group 1 (5.21 ± 4.76 and 3.38 ± 3.58, p = 0.002). Body mass indices were 31.9 ± 5.6 and 30.1 ± 4.8 (p = 0.015). Kellgren–Lawrence class, Western Ontario and McMaster Osteoarthritis Index and Short Form-36 scores were more unfavorable in Group 1. Although fall risk was similar, stability and Fourier harmony indices were impaired in Group 1 compared to Group 2 especially when the visual and proprioceptive input was blocked. Conclusions Almost half of the patients with knee osteoarthritis had neuropathic pain which was associated with longer symptom duration and higher age, lower education, higher body mass index, more severe radilogical findings, worse pain perception, lower physical function and quality of life, and lower stability.

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12-Month Cohort Study to Investigate Changes in Patient-Reported Outcomes Pain after Intra-articular Injection of Micro-Fragmented Adipose Tissue for Knee Osteoarthritis

Biologic Orthopedics Journal ◽

10.22374/boj.v3i1.13 ◽

2021 ◽

Vol 3 (1) ◽

pp. e19-e28

Author(s):

Nathan Hogaboom ◽

Ella D'Amico ◽

Ken Mautner ◽

Christopher Rogers ◽

Gerard Malanga

Keyword(s):

Quality Of Life ◽

Adipose Tissue ◽

Knee Osteoarthritis ◽

Outcome Measures ◽

Knee Pain ◽

Rating Scale ◽

Numerical Rating Scale ◽

Symptomatic Knee ◽

Patient Reported

BackgroundTo evaluate changes in pain, function, and quality of life after treatment with injected micro-fragmented adipose tissue (MFAT) for knee osteoarthritis in a large cohort of individuals treated at multiple centers. MethodsOne hundred ten individuals were recruited from three private outpatient clinics. Participants had to be diagnosed with symptomatic knee OA (defined by persistent knee pain associated with clinical symptoms of OA and/ or classic imaging findings) and who had not received prior knee surgery or treatment with platelet-rich plasma, cortisone, or hyaluronic acid within the previous 6 weeks. Data from 120 knees were included in the analysis. Outcome measures included Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales (pain, symptoms, activities of daily living [ADL], sports and recreation, quality of life [QOL]) and an 11-point Numerical Rating Scale (NRS) for average knee pain over the past week. Outcomes were collected at baseline and 3, 6, and 12 months. ResultsSignificant increases and decreases in KOOS subscale and NRS scores were observed, respectively, in the cohort as a whole (p< .05). Lower BMI was associated with more significant improvements in pain, sports/recreation, and ADL KOOS subscale scores (p< .05). Greater age was associated with more significant improvements in symptoms and QOL subscale scores (p< .05). ConclusionsA single injection of MFAT improved pain, function, and QOL outcome measures up to 12 months in this cohort for more than half of the participants. Greater BMI and lower age negatively influenced outcomes. It is not known whether improvements continue after this timeframe or why many participants reported little-to-no improvement.

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Effects of weight change and physical activity on knee pain and health-related quality of life in East Asian women aged 50 years and older with knee osteoarthritis: a population-based study

10.21203/rs.2.11017/v1 ◽

2019 ◽

Author(s):

Young Choi ◽

Chongbum Chang ◽

Seung-Baik Kang ◽

Chin Youb Chung ◽

Moon Seok Park ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Knee Osteoarthritis ◽

Knee Pain ◽

Weight Change ◽

Population Based ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Abstract Objective This study aimed to investigate the effects of weight change and physical activity on the level of knee pain and health-related quality of life in East Asian women with knee osteoarthritis using population-based data. Methods A total of 564 women (mean age, 68.2 years, standard deviation, 8.9 years) aged 50 years or older with knee osteoarthritis (Kellgren-Lawrence grade ≥2) were included in the data analyses from the fifth Korea National Health and Nutrition Examination Survey. Data regarding the radiographic grade, weight change during the past year, physical activity, level of knee pain, and health-related quality of life (EuroQOL five-dimension [EQ-5D] index) were collected. Multiple regression analysis was performed to identify factors significantly affecting the level of knee pain and health-related quality of life in subgroups according to the body mass index (BMI) range (≤22.5, between 22.6 and 27.5, and >27.5 kg/m2). Results In women with 22.5 kg/m227.5 kg/m2, weekly hours of moderate-intensity activity showed significant negative correlation with EQ-5D. Conclusions The effects of weight change and physical activity on knee pain and health-related quality of life could be different according to BMI ranges. Well-designed interventions to improve both knee pain and health-related quality of life need to be investigated in future studies that would assess physical activity, diet, and weight changes.

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