(548) A longitudinal analysis of quality of life as a differential treatment outcome in a comprehensive pediatric pain clinic

Ehlers–Danlos syndromes (EDS) are a group of connective tissue disorders that manifest with hyperextensibility of joints and skin, and general tissue fragility. While not a major criterion for clinical diagnosis, pain is a frequently endorsed symptom across subtypes of EDS. As such, the present review aims to summarize research to date on pain characteristics and management, and the relationship between such pain symptomatology and quality of life in pediatric EDS. Characteristics of pain, including theorized etiology, relative intensity and extent of pain are described, as well as descriptions of frequently endorsed pain sites (musculoskeletal, and non-musculoskeletal). Interventions related to the management of musculoskeletal (e.g., pharmaceutical intervention, physical therapy) and non-musculoskeletal pain (e.g., pharmaceutical and psychological interventions) are discussed, highlighting the need for additional research related to pediatric pain management in the context of hypermobility syndromes. In addition, the relationship between pain in pediatric EDS and quality of life is described. Finally, limitations of literature to date are described and recommendations for future lines of research are outlined.

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Factors Associated with Health-Related Quality of Life in Psoriatic Arthritis Patients: A Longitudinal Analysis

Rheumatology and Therapy ◽

10.1007/s40744-021-00349-1 ◽

2021 ◽

Author(s):

Dalifer Freites Nuñez ◽

Alfredo Madrid-García ◽

Leticia Leon ◽

Gloria Candelas ◽

Mercedes Núñez ◽

...

Keyword(s):

Quality Of Life ◽

Psoriatic Arthritis ◽

Longitudinal Analysis ◽

Health Related Quality ◽

Factors Associated ◽

Related Quality ◽

Health Related

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The CASP-19 measure and the Longitudinal Analysis of the Quality of Life in Later Life

The Korean Data Analysis Society ◽

10.37727/jkdas.2021.23.1.333 ◽

2021 ◽

Vol 23 (1) ◽

pp. 333-352

Author(s):

Hyunju Park

Keyword(s):

Quality Of Life ◽

Longitudinal Analysis ◽

Later Life

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Dynamics of quality of life of patients as a method of evaluating surgical treatment outcome in oral and oropharyngeal cancer

Oncologia i radiologia Kazakhstana ◽

10.52532/2663-4864-2021-1-59-31-35 ◽

2021 ◽

Vol 59 (1) ◽

pp. 31-35

Author(s):

N. Trizna ◽

Z. Kaliadich ◽

E. Zhaleika ◽

A. Evmenenko

Keyword(s):

Quality Of Life ◽

Treatment Outcome ◽

Physical Functioning ◽

Oropharyngeal Cancer ◽

Individual Therapy ◽

Quality Of Life Indicators ◽

Eortc Qlq C30 ◽

Oral And Oropharyngeal Cancer ◽

Eortc Qlq

Study of the quality of life indicators is an important part of a comprehensive analysis of new diagnosis, treatment, and prevention methods. It can serve as an additional criterion for selecting individual therapy or rehabilitation, examining the ability to work, and identifying psychological problems. Purpose of the study: The authors took a clinical case to demonstrate the use of внтфьшс monitoring of the quality of life indicators for the assessment of surgical and reconstructive treatment outcome for oral and oropharyngeal cancer. Results: The anticancer treatment effects were reflected in the physical functioning score according to the EORTC QLQ-C30 questionnaire (reduced to 80 points) and some symptomatic scores according to the EORTC QLQ-C30 and EORTC QLQ-H & N35 questionnaires. Medical rehabilitation measures resulted in positive dynamics of physical functioning scores according to the EORTC QLQ-C30 questionnaire (increase to 93.3 points) and symptomatic scores according to the EORTC QLQ-H & N35 questionnaire related to nutrition. At that, the patient has stopped having difficulty eating in public places; his body weight increased. The absence of pain and refusal to take analgesics also testified to successful treatment and improved quality of life. Conclusion: A subjective assessment of the various quality of life aspects in a particular patient provides valuable information about the individual response to the conducted treatment.

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Spinal Cord Stimulation in Treatment of Chronic Benign Pain: Challenges in Treatment Planning and Present Status, a 22-Year Experience

Neurosurgery ◽

10.1227/01.neu.0000192162.99567.96 ◽

2006 ◽

Vol 58 (3) ◽

pp. 481-496 ◽

Cited By ~ 264

Author(s):

Krishna Kumar ◽

Gary Hunter ◽

Denny Demeria

Keyword(s):

Quality Of Life ◽

Spinal Cord ◽

Pain Relief ◽

Success Rate ◽

Spinal Cord Stimulation ◽

Pain Clinic ◽

Axial Component

Abstract OBJECTIVE: To present an in-depth analysis of clinical predictors of outcome including age, sex, etiology of pain, type of electrodes used, duration of pain, duration of treatment, development of tolerance, employment status, activities of daily living, psychological status, and quality of life. Suggestions for treatment of low back pain with a predominant axial component are addressed. We analyzed the complications and proposed remedial measures to improve the effectiveness of this modality. METHODS: Study group consists of 410 patients (252 men, 58 women) with a mean age of 54 years and a mean follow-up period of 97.6 months. All patients were gated through a multidisciplinary pain clinic. The study was conducted over 22 years. RESULTS: The early success rate was 80% (328 patients), whereas the long-term success rate of internalized patients was 74.1% (243 patients) after the mean follow-up period of 97.6 months. Hardware-related complications included displaced or fractured electrodes, infection, and hardware malfunction. Etiologies demonstrating efficacy included failed back syndrome, peripheral vascular disease, angina pain, complex regional pain syndrome I and II, peripheral neuropathy, lower limb pain caused by multiple sclerosis. Age, sex, laterality of pain or number of surgeries before implant did not play a role in predicting outcome. The percentage of pain relief was inversely related to the time interval between pain onset and time of implantation. Radicular pain with axial component responded better to dual Pisces electrode or Specify-Lead implantation. CONCLUSION: Spinal cord stimulation can provide significant long-term pain relief with improved quality of life and employment. Results of this study will be effective in better defining prognostic factors and reducing complications leading to higher success rates with spinal cord stimulation.

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Green Light Exposure Improves Pain and Quality of Life in Fibromyalgia Patients: A Preliminary One-Way Crossover Clinical Trial

Pain Medicine ◽

10.1093/pm/pnaa329 ◽

2020 ◽

Author(s):

Laurent Martin ◽

Frank Porreca ◽

Elizabeth I Mata ◽

Michelle Salloum ◽

Vasudha Goel ◽

...

Keyword(s):

Quality Of Life ◽

Clinical Trial ◽

White Light ◽

Light Emitting Diodes ◽

Green Light ◽

Pain Clinic ◽

Mcgill Pain Questionnaire ◽

Light Emitting ◽

White Light Emitting Diodes

Abstract Objective Fibromyalgia is a functional pain disorder in which patients suffer from widespread pain and poor quality of life. Fibromyalgia pain and its impact on quality of life are not effectively managed with current therapeutics. Previously, in a preclinical rat study, we demonstrated that exposure to green light-emitting diodes (GLED) for 8 hours/day for 5 days resulted in antinociception and reversal of thermal and mechanical hypersensitivity associated with models of injury-related pain. Given the safety of GLED and the ease of its use, our objective is to administer GLED as a potential therapy to patients with fibromyalgia. Design One-way crossover clinical trial. Setting United States. Method We enrolled 21 adult patients with fibromyalgia recruited from the University of Arizona chronic pain clinic who were initially exposed to white light-emitting diodes and then were crossed over to GLED for 1 to 2 hours daily for 10 weeks. Data were collected by using paper surveys. Results When patients were exposed to GLED, but not white light-emitting diodes, they reported a significant reduction in average pain intensity on the 10-point numeric pain scale. Secondary outcomes were assessed by using the EQ-5D-5L survey, Short-Form McGill Pain Questionnaire, and Fibromyalgia Impact Questionnaire and were also significantly improved in patients exposed to GLED. GLED therapy was not associated with any measured side effects in these patients. Conclusion Although the mechanism by which GLED elicits pain reduction is currently being studied, these results supporting its efficacy and safety merit a larger clinical trial.

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PCV26 Quality of Life Improves More for People Who Receive Proactive Absolute Cardiac Risk Management in a Rapid Access Chest Pain Clinic Compared to Usual Care

Value in Health Regional Issues ◽

10.1016/j.vhri.2020.07.044 ◽

2020 ◽

Vol 22 ◽

pp. S30-S31

Author(s):

J.A. Black ◽

J. Sharman ◽

A. Palmer ◽

B. de Graaff ◽

M. Hensher ◽

...

Keyword(s):

Quality Of Life ◽

Risk Management ◽

Chest Pain ◽

Usual Care ◽

Cardiac Risk ◽

Pain Clinic ◽

Rapid Access

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Plasma in Cancer Treatment

Cancers ◽

10.3390/cancers12092617 ◽

2020 ◽

Vol 12 (9) ◽

pp. 2617

Author(s):

Angela Privat-Maldonado ◽

Annemie Bogaerts

Keyword(s):

Quality Of Life ◽

Treatment Outcome ◽

Cancer Treatment ◽

Cancer Patients ◽

Cause Of Death ◽

Resistance To Treatment ◽

Development Of Resistance ◽

Current Therapies ◽

As Toxicity

Cancer is the second leading cause of death worldwide, and while science has advanced significantly to improve the treatment outcome and quality of life in cancer patients, there are still many issues with the current therapies, such as toxicity and the development of resistance to treatment [...]

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