Hair for a long-term biological indicator tissue for assessing the strontium nutritional status of men and women

2017 ◽  
Vol 42 ◽  
pp. 11-17 ◽  
Author(s):  
J. Prejac ◽  
V. Višnjević ◽  
A.A. Skalny ◽  
A.R. Grabeklis ◽  
N. Mimica ◽  
...  
2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1063-1063
Author(s):  
Berislav Momčilović ◽  
Juraj Prejac ◽  
Ninoslav Mimica

Abstract Objectives Short-term biological indicator of urinary Mg and Ca excretion helps us to assess human body Mg and Ca nutritional status. In this study, we used the long-term biological indicator tissue of hair to assess Mg and Ca human body nutritional status. Methods Hair Mg and Ca were analyzed in 1073 healthy white adult Caucasians [734 women (♀) and 339 men (♂)] consuming common mid-European diet, with the ICP MS. The log transformed data on hair magnesium and calcium were analyzed with median derivatives bioassay. Results The median values (μg·g−1) were ♀Mg 137.2 and ♂Mg 47.1, and ♀Ca 1721.4 and ♂Ca 492.0, respectively. The linear (adequate) reference ranges of the sigmoid saturation curve for magnesium were ♀Mg 29.7–270.6 and ♂Mg 20.5–90.2, whereas these ranges for calcium were ♀Ca 487.7–4426.8 and ♂Ca 261.1–816.4. The magnesium to calcium (Mg/Ca) ratio in women appears fairly constant along the sigmoid linear segment range (about 0.067), and in difference to the constantly increasing Mg/Ca ratio in men - from 0.078 at the start of the linear segment to 0.096 at the median and 0.1105 before leveling at the top of the curve. Conclusions Women tend to accumulate much more Ca in their hair than men. The results suggest how hair Mg concentration should not be below 29.7 and 20.5 or above 270.6 and 90.2 μg·g−1 in women and men, respectively. Similarly, Ca hair concentrations should be not below 487.7 and 261.1 and higher than 4456.8 and 816.4 in women and men, respectively. The possible health effects of the observed sex related metabolic difference between men and women remains to be elucidated. Funding Sources The authors received no specific funding for this work.


2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Berislav Momcilovic ◽  
Juraj Prejac ◽  
Vjeran Višnjević ◽  
Ninoslav Mimica ◽  
Anatoly Skalny

2007 ◽  
Vol 62 (3) ◽  
pp. 271-275 ◽  
Author(s):  
H. THEOBALD ◽  
P.E. WÄNDELL

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1626
Author(s):  
Catalina Ballestero-Fernández ◽  
Gregorio Varela-Moreiras ◽  
Natalia Úbeda ◽  
Elena Alonso-Aperte

The only available treatment for celiac disease is life-long gluten exclusion. We conducted a cross-sectional age- and gender-matched study in 64 celiac adults on a long-term (>1 year) gluten-free diet and 74 non-celiac volunteers from Spain, using dietary, anthropometric, and biochemical parameters, as well as assessing bone mineral density and physical activity. Celiac adults had deficient intake (below 2/3 of the recommended intake) for folates, vitamin E, and iodine and low intake of calcium (below 80% of the recommended intake). Iron intake was also below 2/3 of the recommended intake in celiac women. Vitamin D intake was extremely low, and 34% of celiac patients had moderately deficient plasma levels. According to bone mineral density, celiac women may be more prone to osteopenia and osteoporosis. However, we found a perfectly analogous nutritional status scenario in celiac as compared to healthy volunteers, with the dietary deviations found being similar to those of the Spanish population, i.e., both groups followed a high-lipid, high-protein, and low-carbohydrate diet. Values for biochemical parameters were found within the reference ranges. Celiac disease had no influence on body weight, but body fat in celiac patients tended to be higher. According to our results, vitamin D, calcium, folates, vitamin E, iodine, and iron nutritional status should be specifically assessed and monitored in the celiac population.


Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3598
Author(s):  
Ga Hee Kim ◽  
Kee Don Choi ◽  
Yousun Ko ◽  
Taeyong Park ◽  
Kyung Won Kim ◽  
...  

Background/Aim: We investigated the oncologic outcomes in elderly patients who underwent endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) by focusing on the impact of comorbidities, sarcopenia, and nutritional status. Methods: Between 2005 and 2016, 280 patients aged ≥ 80 years with 289 EGCs underwent ESD at a tertiary care center. The short- and long-term survival outcomes were assessed. Cox regression analysis was used to identify factors associated with survival, including clinicopathologic factors and abdominal muscle area measured by computed tomography. Results: The rates of en bloc, R0, and, curative resection were 99.3%, 90.0%, and 69.2%, respectively. The rates of post-ESD bleeding and perforation rates were 2.1% and 3.1%, respectively, and no cases showed significant life-threatening adverse events. Over a median follow-up period of 70.5 months, the 3- and 5-year overall survival (OS) rates were 89.5% and 77.1%, respectively; of the114 patients who died, only four (3.5%) were due to gastric cancer. A total of 173 (61.8%) had sarcopenia, and they had lower rates of 3-year (88.4% vs. 91.4%) and 5-year (73.1% vs. 84.0%; p = 0.046) OS than did those without sarcopenia. In multivariable analyses, prognostic nutritional index (hazard ratio [HR], 0.93; 95% confidence interval [CI]: 0.90–0.98; p = 0.002) and Charlson comorbidity index (HR 1.19; 95% CI: 1.03–1.37; p = 0.018) were significant factors associated with overall survival. Conclusions: ESD was a feasible and safe therapeutic method to use in elderly patients, whose long-term survival was significantly associated with nutritional status and comorbidities. These results suggest the need for a possible extension of the curative criteria for ESD in elderly patients with EGC.


2021 ◽  
pp. oemed-2020-107094
Author(s):  
Kathryn Badarin ◽  
Tomas Hemmingsson ◽  
Lena Hillert ◽  
Katarina Kjellberg

ObjectivesMusculoskeletal pain (MSP) is prevalent among the workforce. This study investigates the long-term association between physical workload (PWL) and increased frequency of MSP among male and female employees with pre-existing occasional MSP.MethodsThis study uses the Stockholm Public Health cohort survey data from the baseline 2006. The sample includes 5715 employees with baseline occasional MSP (no more than a few days per month). Eight PWL exposures and overall PWL were estimated using a job-exposure matrix (JEM). The JEM was assigned to occupational titles from a national register in 2006. Follow-up survey data on frequent MSP (a few or more times a week) were collected from 2010. Logistic regressions produced sex-specific ORs with 95% CIs and were adjusted for education, health conditions, psychological distress, smoking, BMI, leisure-time physical activity and decision authority.ResultsAssociations were observed between several aspects of heavy PWL and frequent MSP for men (eg, OR 1.57, 95% CI 1.13 to 2.20, among those in the highest exposure quartile compared with those in the lowest quartile for heavy lifting) and women (eg, OR 1.76, 95% CI 1.35 to 2.29, among those in the highest exposure quartile compared with those in the the lowest quartile for physically strenuous work). Small changes were observed in the OR after adjustment, but most of the ORs for PWL exposures among the men were no longer statistically significantly increased.ConclusionA high level of exposure to heavy PWL was associated with increased frequency of MSP 4 years later for men and women with baseline occasional pain.


2020 ◽  
Author(s):  
Paul Bingley ◽  
Lorenzo Cappellari ◽  
Konstantinos Tatsiramos

Abstract Using administrative data for the population of Danish men and women, we develop an empirical model which accounts for the joint earnings dynamics of siblings and youth community peers. We provide the first decomposition of the sibling correlation of permanent earnings into family and community effects allowing for life cycle dynamics and extending the analysis to consider other outcomes. We find that family is the most important factor influencing sibling correlations of earnings, education and unemployment. Community background matters for shaping the sibling correlation of earnings and unemployment early in the working life, but its importance quickly diminishes.


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