2138 FRACTIONAL CALCIUM ABSORPTION AND HISTORY OF NEPHROLITHIASIS IN OLDER WOMEN IN THE STUDY OF OSTEOPOROTIC FRACTURES

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Mathew Sorensen ◽  
Brian Eisner ◽  
Katie Stone ◽  
Arnold Kahn ◽  
Li-Yung Lui ◽  
...  
Keyword(s):  
Older Women ◽  
Calcium Absorption ◽  
Osteoporotic Fractures ◽  
History Of ◽  
Fractional Calcium Absorption

Fractional calcium absorption is associated with nephrolithiasis in older women in the Study of Osteoporotic Fractures (SOF)

2011 ◽  
Vol 213 (3) ◽  
pp. S145
Author(s):  
Mathew D. Sorensen ◽  
Brian H. Eisner ◽  
Katie L. Stone ◽  
Arnold J. Kahn ◽  
Li-Yung Lui ◽  
...  
Keyword(s):  
Older Women ◽  
Calcium Absorption ◽  
Osteoporotic Fractures ◽  
Fractional Calcium Absorption

scholarly journals Impact of Calcium Intake and Intestinal Calcium Absorption on Kidney Stones in Older Women: The Study of Osteoporotic Fractures

2012 ◽  
Vol 187 (4) ◽  
pp. 1287-1292 ◽  
Author(s):  
Mathew D. Sorensen ◽  
Brian H. Eisner ◽  
Katie L. Stone ◽  
Arnold J. Kahn ◽  
Li-Yung Lui ◽  
...  
Keyword(s):  
Older Women ◽  
Kidney Stones ◽  
Calcium Intake ◽  
Calcium Absorption ◽  
Osteoporotic Fractures ◽  
Intestinal Calcium Absorption

Insights into Transdermal Drug Delivery: Approaches for Redressal of a Burgeoning Issue of Osteoporosis

2020 ◽  
Vol 20 (10) ◽  
pp. 1682-1695
Author(s):  
Foziyah Zakir ◽  
Kanchan Kohli ◽  
Farhan J. Ahmad ◽  
Zeenat Iqbal ◽  
Adil Ahmad
Keyword(s):  
Drug Delivery ◽  
Transdermal Delivery ◽  
Oral Delivery ◽  
Calcium Absorption ◽  
Early Stage ◽  
Osteoporotic Fractures ◽  
The Novel ◽  
Systemic Delivery ◽  
Primary Focus ◽  
The Cost

Osteoporosis is a progressive bone disease that remains unnoticed until a fracture occurs. It is more predominant in the older age population, particularly in females due to reduced estrogen levels and ultimately limited calcium absorption. The cost burden of treating osteoporotic fractures is too high, therefore, primary focus should be treatment at an early stage. Most of the marketed drugs are available as oral delivery dosage forms. The complications, as well as patient non-compliance, limit the use of oral therapy for prolonged drug delivery. Transdermal delivery systems seem to be a promising approach for the delivery of anti-osteoporotic active moieties. One of the confronting barriers is the passage of drugs through the SC layers followed by penetration to deeper dermal layers. The review focuses on how anti-osteoporotic drugs can be molded through different approaches so that they can be exploited for the skin to systemic delivery. Insights into the various challenges in transdermal delivery and how the novel delivery system can be used to overcome these have also been detailed.

Anorexia Nervosa and Depression in a Woman Blind since the Age of Nine Months

1993 ◽  
Vol 38 (7) ◽  
pp. 469-471 ◽  
Author(s):  
Clifford W. Sharp
Keyword(s):  
Eating Disorders ◽  
Body Image ◽  
Anorexia Nervosa ◽  
Eating Disorder ◽  
Major Depression ◽  
Food Intake ◽  
Older Women ◽  
The Body ◽  
Atypical Presentation ◽  
History Of

A woman aged 58 who has been blind since the age of nine months presented with major depression and a 40 year history of an eating disorder characterized by a restriction of food intake and body disparagement. The case is additional evidence that a specifically visual body image is not essential for the development of anorexia nervosa and supports the view that the concept of body image is unnecessary and unproductive in eating disorders. Greater emphasis should be placed on attitudes and feelings toward the body, and the possibility of an eating disorder should be considered in cases of older women with an atypical presentation.

scholarly journals Pins and Plaster Aren’t Enough: A Call for the Evaluation and Treatment of Patients with Osteoporotic Fractures

2003 ◽  
Vol 88 (8) ◽  
pp. 3482-3486 ◽  
Author(s):  
Ethel S. Siris ◽  
John P. Bilezikian ◽  
Mishaela R. Rubin ◽  
Dennis M. Black ◽  
Richard S. Bockman ◽  
...  
Keyword(s):  
Vitamin D ◽  
Fracture Risk ◽  
Primary Care Physicians ◽  
Osteoporotic Fractures ◽  
Standard Of Care ◽  
Pharmacological Therapy ◽  
Diagnostic Tools ◽  
Osteoporosis Therapy ◽  
Call To Action ◽  
History Of

A history of an osteoporotic fracture is a powerful predictor of future fractures. Older patients who sustain low trauma fractures are candidates for interventions that should include confirmation of the diagnosis of osteoporosis, adequate calcium and vitamin D administration, and use of an osteoporosis therapy that is proven to lower fracture risk. Recently, however, several reports in the literature have indicated that, in general, those physicians who diagnose and treat fractures, i.e. radiologists, orthopedic surgeons, physiatrists, and those who provide general medical care to these fracture patients, the primary care physicians, are not evaluating patients with acute fractures for the presence of osteoporosis and are not prescribing calcium, vitamin D, or specific pharmacological therapy to reduce future fracture risk. These reports suggest that implementation of a standard of care for the subsequent medical management of the older patient with an acute fracture is needed urgently. Diagnostic tools and several effective therapies exist, but these are underused by the physicians who interface with these patients. A call to action is necessary to reduce the human and economic costs associated with this serious and treatable disease.

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