scholarly journals Cost-Effectiveness Evaluation of Acarizax® In Patients with House Dust Mites Induced Allergic Asthma And Allergic Rhinitis In Slovakia

2016 ◽  
Vol 19 (7) ◽  
pp. A554-A555
Author(s):  
R Babela ◽  
J Hahn-Pedersen ◽  
P Pruzinec ◽  
V Uraz
Keyword(s):  
Allergic Rhinitis ◽  
Cost Effectiveness ◽  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mites ◽  
Effectiveness Evaluation ◽  
Dust Mites

scholarly journals The Presence of House Dust Mites in Residences and Classrooms of Students with Allergic Rhinitis

2021 ◽  
Vol 21 (2) ◽  
pp. 138-143
Author(s):  
Suri Dwi Lesmana ◽  
Harianto Harianto ◽  
Reyza Octarient
Keyword(s):  
Allergic Rhinitis ◽  
House Dust ◽  
Health Problem ◽  
Direct Method ◽  
House Dust Mites ◽  
Dust Mites ◽  
Essential Factor ◽  
Skills Lab ◽  
Chronic Stressor ◽  
Large Classrooms

Allergy is still a health problem in Indonesia. One of the manifestations of allergies is allergic rhinitis. Many factors can trigger the recurrence of rhinitis, including exposure to house dust mites. This study aims to identify the population of house dust mites in the classrooms and student residences. This study was participated by 74 FK UNRI students with allergic rhinitis. The samples included dust collected from residences and classrooms consisting of four large classrooms, three small classrooms, four laboratories, two examination rooms, 12 skills lab rooms, and 15 tutorial rooms. Detection of dust was performed using the direct method. The results showed that no classroom (0%) was found with house dust mites. However, there were 37.8% of residences were positive. Based on the result, it can be concluded that the high population of house dust mites in the students’ residences becomes an essential factor as a chronic stressor for allergic rhinitis.

scholarly journals Sensitivity to House Dust Mites Allergens in Patients with Allergic Asthma in Erzincan Province, Turkey

2017 ◽  
Vol 41 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Erhan Zeytun ◽  
Salih Dogan ◽  
Fatih Ozcicek ◽  
Edhem Unver
Keyword(s):  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mites ◽  
Dust Mites

scholarly journals Could FeNO Predict Asthma in Patients with House Dust Mites Allergic Rhinitis?

Medicina ◽  
2020 ◽  
Vol 56 (5) ◽  
pp. 235
Author(s):  
Ioana Adriana Muntean ◽  
Ioana Corina Bocsan ◽  
Stefan Vesa ◽  
Nicolae Miron ◽  
Irena Nedelea ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
House Dust ◽  
Immunoglobulin E ◽  
Biological Evaluation ◽  
House Dust Mites ◽  
Dust Mites ◽  
Persistent Allergic Rhinitis ◽  
Tnf Α ◽  
One Year ◽  
High Level

Background and Objectives: The evolution of allergic rhinitis to asthma is a part of “atopic march”. The aim of this study was to analyze possible predictive markers for asthma occurrence in patients with allergic rhinitis to house dust mites (HDM). Materials and Methods: Fifty-eight patients with persistent allergic rhinitis (PAR) were included. The clinical, biological evaluation and fractionated exhaled nitric oxide (FeNO) measurement were performed at enrolment. The patients were clinically evaluated after one year to determine asthma occurrence. Results: The severity of rhinitis symptoms, levels of total immunoglobulin E (IgE), ICAM-1, VCAM-1, E-selectin and IL-6, but not IL-8 and TNF-α were higher in patients with allergic rhinitis who developed asthma compared to non-asthmatics, but the differences were not significant to considered them as predictive factors for asthma occurrence. The risk of asthma was independently influenced by patients aged over 30 years ((OR-3.74; CI95% 0.86–16.31; p = 0.07), a duration of allergic rhinitis over 12 months ((OR-4.20; CI95% 0.88–20; p = 0.07) and a basal FeNO over 28 parts per billion (pbb) ((OR-18.68; CI95% 3.79–92.05; p < 0.001). Conclusion: Clinical and biological parameters may predict asthma occurrence in patients with persistent allergic rhinitis to HDM. Adult patients with a longer duration of rhinitis symptoms and a high level of FeNO have a greater risk to develop asthma.

Clinical and Immunologic Effects of Sublingual Immunotherapy on Patients with Allergic Rhinitis to House-Dust Mites: 1-Year follow-up Results

2010 ◽  
Vol 24 (4) ◽  
pp. 271-275 ◽  
Author(s):  
Seung-Tae Kim ◽  
Doo Hee Han ◽  
Il Joon Moon ◽  
Chul Hee Lee ◽  
Yang-Gi Min ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
House Dust ◽  
Sublingual Immunotherapy ◽  
House Dust Mites ◽  
Dust Mites

scholarly journals Gambaran Kepadatan Tungau Debu Rumah Sebagai Pencetus Rinitis Alergi pada Anak Panti Asuhan Pekanbaru

2019 ◽  
Vol 13 (1) ◽  
pp. 23
Author(s):  
Yolazenia Yolazenia ◽  
Harianto Harianto ◽  
Iqbal Teguh Riady
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
House Dust ◽  
International Study ◽  
Descriptive Study ◽  
House Dust Mites ◽  
Dust Mites ◽  
High Incidence ◽  
The Mean

Allergic rhinitis should be considered as a serious condition because it can affect the quality of life of patients. In manycases, the most common allergen is house dust mites (HDM). The purpose of this study was to describe the density ofhouse dust mites as triggers of allergic rhinitis in Pekanbaru orphanage children. This is a descriptive study with across sectional approach. Data obtained from interviews using the modified International Study of Asthma and Allergiesof Childhood (ISAAC) questionnaire to know the allergic rhinitis status and examination of house dust samples toidentify HDM in the parasitology laboratory. Sampling was carried out in 4 orphanages Pekanbaru. Allergic rhinitissymptoms were experienced by 81.2% of children in the orphanages and HDM was found with the mean density 9.11/g of dust. HDM was found in all four orphanages and was found to have a high incidence of allergic rhinitis.

scholarly journals Environmental Allergens House Dust Mites-induced Asthma Causes Ferroptosis in the Lungs

2021 ◽  
Author(s):  
Weifeng Tang ◽  
Ming Dong ◽  
Fangzhou Teng ◽  
Jie Cui ◽  
Xueyi Zhu ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Allergic Asthma ◽  
House Dust ◽  
Inflammatory Cell ◽  
Morphological Changes ◽  
Mucus Secretion ◽  
House Dust Mites ◽  
Control Group ◽  
Dust Mites ◽  
Cell Counts

Abstract Background: Studies have indicated that allergens such as house dust mites (HDM) in the environment could induce allergic asthma. Ferroptosis is a newly discovered regulatory cell death characterized by aberrant lipid peroxidation and accumulation of reactive oxygen species (ROS) in cells. However, whether ferroptosis participates in the pathological progress of asthma remains to be elucidated. In this study, we used a HDM-induced mouse asthma model to determine the effect of HDM exposure on allergic asthma and the underlying mechanisms. Methods: Female BALB/c mice were intranasally exposed to HDM to induce allergic asthma. Airway hyperresponsiveness (AHR), lung inflammation and mucus secretion, IgE and cytokine levels as well as inflammatory cell counts in bronchalveolar lavage fluid (BALF) were investigated. In addition, the morphological changes of mitochondria, ROS, glutathione (GSH) levels and changes in ferroptosis pathway proteins in the lung were also determined. Results: HDM exposure increased AHR significantly, and enhanced inflammatory cell infiltration and mucus secretion around the airways. Furthermore, elevated IgE level in BALF, lung eosinophilia, and a concomitant increase in IL-13 and IL-5 in BALF were observed. HDM inhalation increased ROS and decreased GSH level in the lung. HDM inhalation induced dysmorphic small mitochondria with decreased crista, as well as condensed, ruptured outer membranes. Western blot analysis demonstrated that activity of glutathione peroxidase 4 (GPX4) and catalytic subunit solute carrier family 7 member 11 (SLC7A11) decreased significantly, and protein expression of acyl-CoA synthetase long-chain family member 4 (ACSL4) and 15 Lipoxygenase 1 (15-LO1) upregulated prominently compared with mice in normal control group. Conclusions: These in all indicated that the AHR, airway inflammation, lipid peroxidation and ROS level increased in HDM-induced asthma, and HDM inhalation caused ferroptosis in the lungs, which helped to form a better understanding of the pathogenesis of allergic asthma and targeted treatment strategies.

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